A mechanistic study on tablet ejection force and its sensitivity to lubrication for pharmaceutical powders

No abstract is available for this paper.

• Publication year

  2018

• Venue

  International journal of pharmaceutics

• Publication date

  2018-05-30

• Fields of study

  Medicine, Materials Science

• Identifiers
  DOI 10.1016/j.ijpharm.2018.03.064PMID 29621552
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Gaining insight into tablet capping tendency from compaction simulation.

  2017cited by this paper
• ggplot2 - Elegant Graphics for Data Analysis (2nd Edition)

  2017cited by this paper
• Dependence of ejection force on tableting speed—A compaction simulation study

  2015cited by this paper
• Assessing materials' tablet compaction properties using the Drucker–Prager Cap model

  2014cited by this paper
• Scale-up model describing the impact of lubrication on tablet tensile strength.

  2010cited by this paper
• Lubrication in tablet formulations.

  2010cited by this paper
• Experiments on corn pressure in silo cells – translation and comment of Janssen's paper from 1895

  2005cited by this paper
• Evaluation of the effects of tableting speed on the relationships between compaction pressure, tablet tensile strength, and tablet solid fraction.

  2005cited by this paper
• Analysis of tablet compaction. I. Characterization of mechanical behavior of powder and powder/tooling friction.

  2004cited by this paper
• Benefits of die-wall instrumentation for research and development in tabletting.

  2004cited by this paper
• Wall Friction and its Effects on the Density Distribution in the Compaction of Pharmaceutical Excipients

  2003cited by this paper
• Compression Behavior of Orthorhombic Paracetamol

  1998cited by this paper
• The effects of wall friction in powder compaction

  1998cited by this paper
• The internal form of compacted ceramic components: a comparison of a finite element modelling with experiment

  1996cited by this paper
• The measurement of die wall forces to determine the minimum concentration of lubricant needed for tablet formulation

  1984cited by this paper
• The determination of the coefficient of dynamic friction of organic powder compacts on steel

  1983cited by this paper
• Friction coefficients of tablet masses

  1981cited by this paper
• Tablet lubricants I. Theory and modes of action

  1981cited by this paper
• Evaluation of some lubricants by the comparison of friction coefficients and tablet properties.

  1981cited by this paper
• Internal friction of compressed pharmaceutical powders observed in terms of the die wall pressure.

  1980cited by this paper
• Powder—wall friction: The effects of orientation of wall grooves and wall lubricants

  1977cited by this paper
• PHYSICS OF TABLET COMPRESSION. XIV. LATERAL DIE WALL PRESSURE DURING AND AFTER COMPRESSION.

  1965cited by this paper
• The Friction and Lubrication of Solids

  1964cited by this paper
• RADIAL PRESSURES IN POWDER COMPACTION

  1960cited by this paper

• Experimental investigation of compression and wetting behavior of liquisolid systems with different porous carriers prepared via fluid bed processing

  2025cites this paper
• Mannitol in direct compression: Production, functionality, critical material attributes and co-processed excipients.

  2025cites this paper
• Modulating hygroscopicity and compression performance in chewable mannitol-xylitol tablets: Effects of relative humidity and magnesium stearate

  2025cites this paper
• Data-efficient prediction in tableting using word embeddings and empirically-guided neural networks

  2025cites this paper
• Difference in Tableting of Lubricated Spray-Dried Mannitol and Fluid-Bed Granulated Isomalt

  2025cites this paper
• Tablet Binding: Causes, Analyses, and Strategic Avoidance.

  2025cites this paper
• Numerical Analysis of Compression Properties of the Binary Mixture of Powder with Different Particle Plasticities

  2024cites this paper
• Evaluation of the Ejection Pressure for Tracking Internal Cracks during Compaction in Bilayer Tablet Formulations Using Experimental and Finite Element Methods

  2024influential citation
• A systematic investigation of external lubrication of mini-tablets on a rotary tablet press with focus on the tensile strength.

  2024cites this paper
• Influence of colloidal silicon dioxide‑magnesium stearate interaction on flow and compaction behavior of an MCC-Lactose binary mixture

  2024cites this paper
• Tableting of coated multiparticulates: Influences of punch face configurations.

  2024cites this paper
• How can the heterogeneous distribution of a component in low concentration in the mixture at the radial surface of a tablet modify the mechanical properties of a tablet?

  2024cites this paper
• Magnesium Stearate Fatty Acid Composition, Lubrication Performance and Tablet Properties

  2024cites this paper
• Simplest Mechanism Builder Algorithm (SiMBA): An Automated Microkinetic Model Discovery Tool

  2024cites this paper
• Tablet ejection: A systematic comparison between force, static friction, and kinetic friction.

  2024cites this paper
• A Method for the Tensile Strength Prediction of Tablets with Differing Powder Plasticities.

  2024cites this paper
• Compression properties of bimodal powders with different plasticities in the elastoplastic powder compression process: A numerical analysis

  2023cites this paper
• Upscaling of external lubrication from a compaction simulator to a rotary tablet press.

  2023cites this paper
• Study of Diminutive Granules as Feed Powders for Manufacturability of High Drug Load Minitablets.

  2023cites this paper
• Lactose in tablets: functionality, critical material attributes, applications, modifications and co-processed excipients.

  2023cites this paper
• Sodium lauryl sulfate as lubricant in tablets formulations: is it worth?

  2023cites this paper
• Effect of Material Properties and Variability of Mannitol on Tablet Formulation Development

  2023cites this paper
• Leveraging a multivariate approach towards enhanced development of direct compression extended release tablets.

  2023cites this paper
• A Systematic Investigation and Suggested Remedies for a Defective Marketed Solid Dosage Form.

  2023cites this paper
• Compressibility behavior of pioglitazone hydrochloride in mannitol-based formulations: An investigation using compaction simulator and QbD approach.

  2023cites this paper
• Impact of magnesium stearate physical and chemical variabilities on pharmaceutical powder flow and tablet physical properties

  2023cites this paper
• Successful Formulation Window for the design of pharmaceutical tablets with required mechanical properties.

  2023cites this paper
• Impact of Vertical Blender Unit Parameters on Subsequent Process Parameters and Tablet Properties in a Continuous Direct Compression Line

  2022cites this paper
• Screening of lubricants towards their applicability for external lubrication.

  2022cites this paper
• MUPS Tableting—Comparison between Crospovidone and Microcrystalline Cellulose Core Pellets

  2022cites this paper
• Stress shielding effect in pressure-assisted binder jetting

  2022cites this paper
• Downstream Processing of Amorphous and Co-Amorphous Olanzapine Powder Blends

  2022cites this paper
• Continuous measurement of die wall pressure in a rotary tablet machine.

  2022cites this paper
• Impact of Lubrication on Key Properties of Orodispersible Minitablets in Comparison to Conventionally Sized Orodispersible Tablets.

  2022cites this paper
• Evaluation of Alternative Metallic Stearates as Lubricants in Pharmaceutical Tablet Formulation

  2022cites this paper
• A Multivariate Formulation and Process Development Platform for Direct Compression.

  2022cites this paper
• Effect of feedframe on lubricant sensitivity during upscaling from a compaction simulator to a rotary tablet press.

  2022cites this paper
• Simplifying Johanson's Roller Compaction Model to Build a "Virtual Roller Compactor" as a Predictive Tool - Theory and Practical Application.

  2021cites this paper
• A Scale-Up, Phenomenological Model Incorporating the Effect of Both Feed Frame Lubrication and Tumble Blending-Driven Lubrication on Tablet Mechanical Strength.

  2021cites this paper
• Improving Tableting Performance of Lactose Monohydrate by Fluid-Bed Melt Granulation Co-Processing

  2021cites this paper
• An update on microcrystalline cellulose in direct compression: Functionality, critical material attributes, and co-processed excipients.

  2021cites this paper
• Utilization of a compaction simulator to formulate mini-tablets containing high dose of acyclovir

  2021cites this paper
• Research on the powder classification and the key parameters affecting tablet qualities for direct compaction based on powder functional properties

  2021cites this paper
• Analytical approach for lubricant characterization of excipients using the surface replication method

  2021cites this paper
• The effect of relative humidity and formulation variables on chewable xylitol-sorbitol tablets.

  2021cites this paper
• Evaluation of an external lubrication system implemented in a compaction simulator.

  2020cites this paper
• BIND (II), characterization of die wall surface modifications for good manufacturing using the surface replication method

  2020cites this paper
• Flow Function Of Pharmaceutical Powders At Low Stress Conditions Can Be Inferred Using A Simple Flow-Through-Orifice Device.

  2020cites this paper
• BIND, a novel analytical approach for monitoring powder adhesion at the die wall with use of the surface replication method.

  2019cites this paper
• Machine learning modelling of wet granulation scale-up using compressibility, compactibility and manufacturability parameters

  2019cites this paper
• Impact of Die Wall Material on the Mechanical Properties of Paracetamol Tablets.

  2019cites this paper