Optimal Perfusion Flow Rates for Cardiopulmonary Bypass

B. A. Mitchell

Published 1990 in The Journal of ExtraCorporeal Technology

ABSTRACT

In addressing the subject of optimal perfusion flow rates for cardiopulmonary bypass, we must be reminded of a remark made by a pioneer in the physiology of cardiac surgery, Dr. Frank Gollan, who said “We cannot command nature except by obeying her” (1). During extracorporeal circulation (ECC), we try to closely approximate the physiologic state, “but we never duplicate.” During my travels as a perfusionist, both in the United States and abroad, I have noted that flow rates during cardiopulmonary bypass vary widely from a low flow of 1.61/m2/min in adults to a high flow of over 3.0 1/m2/min in infants and children; flow rates were not written in stone and handed down to us. Flow rates are “optimal,” thus the variations we see are appropriate to the time, place and circumstances that prevail.

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