Full-field strain distribution in multi-vertebra spine segments: An in vitro application of digital image correlation.

The biomechanics of the spine is experimentally assessed in terms of range of motion and overall stiffness. Quantification of the surface strain distribution is currently limited either to the vertebrae or the discs, whereas a full-field approach to measure the strain distribution in a multi-vertebra segment is currently missing. The aim of this work was to explore the feasibility of using Digital Image Correlation (DIC) to measure the strain distribution simultaneously on the vertebral bodies and the intervertebral discs of spine segments in different loading configurations. Three porcine spine segments were tested. A white-on-black speckle pattern was prepared which covered the hard and soft tissues. Two different loading configurations (flexion and lateral bending) were reproduced, while two sides of the spine were analyzed with DIC. Measurements were successfully performed on the entire region of interest of all specimens, in both configurations. The DIC analysis highlighted the strain gradients present on the spine segments including tension and compression associated with bending, the direction of principal strains in the different regions, as well as bulging of the discs under compression. Strains of tens of thousands microstrain were measured in the discs, and below 2000 microstrain in the bone. This work showed the feasibility of applying DIC on spine segments including hard and soft tissues. It also highlights the need for a full-field investigation, because of the strain inhomogeneity in the vertebrae and discs.

• Publication year

  2017

• Venue

  Medical Engineering and Physics

• Publication date

  2017-12-08

• Fields of study

  Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.1016/j.medengphy.2017.11.003PMID 29229402
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Clinical Biomechanics of the Spine.

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• Application of the digital volume correlation technique for the measurement of displacement and strain fields in bone: a literature review.

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• EXPERIMENTAL METHODS FOR THE BIOMECHANICAL INVESTIGATION OF THE HUMAN SPINE: A REVIEW

  2014cited by this paper
• A practical approach to optimizing the preparation of speckle patterns for digital-image correlation

  2014cited by this paper
• An effective procedure to create a speckle pattern on biological soft tissue for digital image correlation measurements.

  2014cited by this paper
• Strain distribution in the lumbar vertebrae under different loading configurations.

  2013influential reference
• Digital Volume Correlation for Study of the Mechanics of Whole Bones.

  2012cited by this paper
• Short-term Morbidity and Mortality Associated With Correction of Thoracolumbar Fixed Sagittal Plane Deformity: A Report from the Scoliosis Research Society Morbidity and Mortality Committee

  2011cited by this paper
• Biomechanical in vitro evaluation of the complete porcine spine in comparison with data of the human spine

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  2009cited by this paper
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  2009cited by this paper
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  2009cited by this paper
• A method to obtain surface strains of soft tissues using a laser scanning device.

  2008cited by this paper
• Thermal Waves for Imaging of Defects with Lockin‐Speckle Interferometry

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  2007cited by this paper
• A Technique for Dynamic Tensile Testing of Human Cervical Spine Ligaments

  2006cited by this paper
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  2005cited by this paper
• Biomechanical Role of Lumbar Spine Ligaments in Flexion and Extension: Determination Using a Parallel Linkage Robot and a Porcine Model

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  2002cited by this paper
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  2001cited by this paper
• Are Sheep Spines a Valid Biomechanical Model for Human Spines?

  1997cited by this paper
• Cervical vertebral strain measurements under axial and eccentric loading.

  1995cited by this paper
• Reconstruction of bone loading conditions from in vivo strain measurements.

  1995cited by this paper
• Mechanical behavior of the human lumbar and lumbosacral spine as shown by three-dimensional load-displacement curves.

  1994cited by this paper
• Strain gauge reinforcement of plastics

  1990cited by this paper
• Mechanical function of the human lumbar interspinous and supraspinous ligaments.

  1990cited by this paper
• Proximal femoral surface strain gauge analysis of a new epiphyseal prosthesis.

  1989cited by this paper
• Mechanical behavior of the human lumbar spine. II. Fatigue strength during dynamic compressive loading

  1987cited by this paper
• Surface strain on human intervertebral discs

  1987influential reference
• The distribution of surface strain in the cadaveric lumbar spine.

  1978cited by this paper
• Clinical Biomechanics of the Spine

  1978cited by this paper
• Growth of human intervertebral discs and vertebral bodies.

  1975cited by this paper
• Bone deformation recorded in vivo from strain gauges attached to the human tibial shaft.

  1975cited by this paper

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