Spectral focusing dual-comb coherent anti-Stokes Raman spectroscopic imaging.

Coherent Raman microscopy provides label-free imaging by interrogating the intrinsic vibration of molecules. Here, we present a concept in a 100 MHz dual-comb scheme to facilitate high-speed and broadband coherent anti-Stokes Raman spectroscopic imaging based on down-converted, automatically varying delay-time in spectral focusing excitation. A rapid measurement of vibrational microspectroscopy on submicrosecond scale over a spectral span ∼700  cm-1 with a refresh rate of 1.2 kHz provides access to well-resolved molecular signatures within the fingerprint region. We demonstrate hyperspectral images of a mixture of spatially inhomogeneous distributions of chemical substances.

• Publication year

  2017

• Venue

  Optics Letters

• Publication date

  2017-02-11

• Fields of study

  Materials Science, Medicine, Physics, Chemistry

• Identifiers
  DOI 10.1364/OL.42.003634arXiv 1702.03404PMID 28914920
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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