Everolimus alters white matter diffusion in tuberous sclerosis complex

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Neurology

• Publication date

  2012-02-21

• Fields of study

  Medicine

• Identifiers
  DOI 10.1212/WNL.0b013e318247ca8dPMID 22262746
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2012cited by this paper
• Diffusion features of white matter in tuberous sclerosis with tractography.

  2010cited by this paper
• Diffusion tensor imaging identifies changes in normal-appearing white matter within the epileptogenic zone in tuberous sclerosis complex.

  2010cited by this paper
• Everolimus for subependymal giant-cell astrocytomas (SEGAs) in tuberous sclerosis (TS).

  2010cited by this paper
• Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors

  2010cited by this paper
• Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis.

  2010cited by this paper
• Diffusion Tensor Imaging of Commissural and Projection White Matter in Tuberous Sclerosis Complex and Correlation with Tuber Load

  2010cited by this paper
• Regression of Subependymal Giant Cell Astrocytoma With Rapamycin in Tuberous Sclerosis Complex

  2008cited by this paper
• Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function

  2008cited by this paper
• The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis

  2008cited by this paper
• Clinicopathological and immunohistochemical findings in an autopsy case of tuberous sclerosis complex

  2008cited by this paper
• Tuberous sclerosis

  2008cited by this paper
• A Mouse Model of Tuberous Sclerosis: Neuronal Loss of Tsc1 Causes Dysplastic and Ectopic Neurons, Reduced Myelination, Seizure Activity, and Limited Survival

  2007cited by this paper
• Neuroanatomical correlates of memory deficits in tuberous sclerosis complex.

  2007cited by this paper
• Characteristics of Abnormal Diffusivity in Normal-Appearing White Matter Investigated with Diffusion Tensor MR Imaging in Tuberous Sclerosis Complex

  2007cited by this paper
• Complexity of the TOR signaling network.

  2006cited by this paper
• The tuberous sclerosis complex.

  2006cited by this paper
• Rapamycin causes regression of astrocytomas in tuberous sclerosis complex

  2006cited by this paper
• DtiStudio: Resource program for diffusion tensor computation and fiber bundle tracking

  2006cited by this paper
• FDG‐PET/MRI Coregistration and Diffusion‐Tensor Imaging Distinguish Epileptogenic Tubers and Cortex in Patients with Tuberous Sclerosis Complex: A Preliminary Report

  2006cited by this paper
• Diffusion tensor imaging in children and adolescents with tuberous sclerosis

  2005cited by this paper
• Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2

  2005cited by this paper
• Brain Abnormalities in Tuberous Sclerosis Complex

  2004cited by this paper
• Fine structure of atypical cells in tuberous sclerosis

  2004cited by this paper
• Molecular Pathogenesis of Tuber Formation in Tuberous Sclerosis Complex

  2004cited by this paper
• Widespread anatomical abnormalities of grey and white matter structure in tuberous sclerosis

  2001cited by this paper
• Tuberous Sclerosis Complex Consensus Conference: Revised Clinical Diagnostic Criteria

  1998cited by this paper
• Automated image registration: I. General methods and intrasubject, intramodality validation.

  1998cited by this paper
• Tuberous sclerosis in a 20-week gestation fetus: immunohistochemical study

  1997cited by this paper
• Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34.

  1997cited by this paper
• Diffusion tensor MR imaging of the human brain.

  1996cited by this paper
• Tuberous sclerosis.

  1994cited by this paper
• Identification and characterization of the tuberous sclerosis gene on chromosome 16

  1993cited by this paper
• Immunocytochemical studies on a fetal brain of tuberous sclerosis.

  1985cited by this paper

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  2025cites this paper
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  2024cites this paper
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  2024cites this paper
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  2023cites this paper
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  2023cites this paper
• Systematic review of mTOR inhibitor treatment, biomarkers and prophylaxis for tuberous sclerosis complex-associated seizures.

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  2022cites this paper
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  2022cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
• Corpus Callosum White Matter Diffusivity Reflects Cumulative Neurological Comorbidity in Tuberous Sclerosis Complex

  2018cites this paper
• From bedside to bench and back: Translating ASD models.

  2018cites this paper
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  2018influential citation
• mTOR inhibitor therapy as a disease modifying therapy for tuberous sclerosis complex

  2018cites this paper
• Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors

  2018cites this paper
• Research advances in hereditary epilepsy and precision drug therapy

  2017cites this paper
• [Research advances in hereditary epilepsy and precision drug therapy].

  2017cites this paper
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  2017cites this paper
• Surveillance and management of patients with tuberous sclerosis complex.

  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Treatment of Neurogenetic Developmental Conditions: From 2016 into the Future.

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Translational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.

  2016cites this paper
• Tuberous sclerosis complex: Five new things.

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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• Conventional and advanced MRI features of pediatric intracranial tumors: supratentorial tumors.

  2013cites this paper
• Diffusion tensor imaging and related techniques in tuberous sclerosis complex: review and future directions.

  2013cites this paper
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  2012cites this paper
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