Membrane buckling induced by curved filaments.

We present a novel buckling instability relevant to membrane budding in eukaryotic cells. In this mechanism, curved filaments bind to a lipid bilayer without changing its intrinsic curvature. As more and more filaments adsorb, newly added ones are more and more strained, which destabilizes the flat membrane. We perform a linear stability analysis of filament-dressed membranes and find that the buckling threshold is within reasonable in vivo parameter values. We account for the formation of long tubes previously observed in cells and in purified systems. We study strongly deformed dressed membranes and their bifurcation diagram numerically. Our mechanism could be validated by a simple experiment.

• Publication year

  2009

• Venue

  Physical Review Letters

• Publication date

  2009-03-19

• Fields of study

  Biology, Materials Science, Medicine, Physics

• Identifiers
  DOI 10.1103/PhysRevLett.103.038101arXiv 0903.3363PMID 19659322
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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