The EphA8 receptor induces sustained MAP kinase activation to promote neurite outgrowth in neuronal cells

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Oncogene

• Publication date

  2005-06-16

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.onc.1208584PMID 15782114
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Oncogene].

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  2003cited by this paper
• Eph receptors and ephrins.

  2003cited by this paper
• The p110γ PI‐3 kinase is required for EphA8‐stimulated cell migration

  2003cited by this paper
• The p110 gamma PI-3 kinase is required for EphA8-stimulated cell migration.

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• Manipulation of EphB2 Regulatory Motifs and SH2 Binding Sites Switches MAPK Signaling and Biological Activity*

  2003influential reference
• EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis

  2003cited by this paper
• Identification of an enhancer region in the mouse ephA8 locus directing expression to the anterior region of the dorsal mesencephalon

  2003cited by this paper
• Mechanisms and functions of eph and ephrin signalling

  2002cited by this paper
• The role of the Eph-ephrin signalling system in the regulation of developmental patterning.

  2002cited by this paper
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  2002cited by this paper
• Cell sorting in animal development: signalling and adhesive mechanisms in the formation of tissue boundaries.

  2002cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
• FEBS Lett

  2000cited by this paper
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  1999cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1976cited by this paper

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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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• EphA Receptors Form a Complex with Caspase-8 to Induce Apoptotic Cell Death

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  2014cites this paper
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