Drugs Affecting Homocysteine Metabolism

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Drugs

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.2165/00003495-200262040-00005
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Plasma levels of the atherogenic amino acid homocysteine in postmenopausal women with breast cancer treated with tamoxifen

  2006cited by this paper
• Plasma homocysteine concentrations in patients with Type 1 diabetes

  2003cited by this paper
• RISK FACTOR MODIFICATION FOR CARDIAC DISEASE

  2000cited by this paper
• Effects of a high-fat-sucrose diet on enzymes in homocysteine metabolism in the rat.

  2000cited by this paper
• Hyperhomocysteinemia in type 2 diabetes mellitus: cardiovascular risk factors and effect of treatment with folic acid and pyridoxine.

  2000cited by this paper
• Serum homocysteine concentration as an indicator of survival in patients with acute coronary syndromes.

  2000influential reference
• The effects of hormone replacement therapy and raloxifene on C-reactive protein and homocysteine in healthy postmenopausal women: a randomized, controlled trial.

  2000cited by this paper
• The effect of estrogen replacement therapy on total plasma homocysteine in healthy postmenopausal women.

  2000cited by this paper
• Increased plasma homocysteine after menopause.

  2000cited by this paper
• Increased intake of calcium reverses vitamin B12 malabsorption induced by metformin.

  2000cited by this paper
• Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial.

  2000cited by this paper
• Homocysteine, B vitamins, and coronary artery disease.

  2000cited by this paper
• Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey.

  2000cited by this paper
• Serum homocysteine increases after therapy with fenofibrate or bezafibrate.

  1999cited by this paper
• Homocyst(e)ine and Cardiovascular Disease: A Critical Review of the Epidemiologic Evidence

  1999cited by this paper
• Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins.

  1999cited by this paper
• Hyperhomocysteinemia and the endocrine system: implications for atherosclerosis and thrombosis.

  1999cited by this paper
• Systematic review on the risk and benefit of different cholesterol-lowering interventions.

  1999cited by this paper
• Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis

  1999cited by this paper
• Total plasma homocysteine and insulin levels in type 2 diabetic patients with secondary failure to oral agents.

  1999cited by this paper
• Treatment of hyperhomocysteinemia with folic acid and vitamins B12 and B6 attenuates thrombin generation.

  1999cited by this paper
• Three months supplementation of hyperhomocysteinaemic patients with folic acid and vitamin B6 improves biological markers of endothelial dysfunction

  1999cited by this paper
• Effect of folic acid and betaine on fasting and postmethionine‐loading plasma homocysteine and methionine levels in chronic haemodialysis patients

  1999cited by this paper
• Implication of fibrate therapy for homocysteine.

  1999cited by this paper
• Fibrates, dyslipoproteinaemia and cardiovascular disease.

  1999cited by this paper
• Homocysteine and short-term risk of myocardial infarction and stroke in the elderly: the Rotterdam Study.

  1999cited by this paper
• Plasma Homocysteine in Women Taking Hormone Replacement Therapy: The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial

  1999cited by this paper
• Folic acid improves arterial endothelial function in adults with hyperhomocystinemia.

  1999cited by this paper
• Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group.

  1999cited by this paper
• Effect of short-term vitamin (folic acid, vitamins B6 and B12) administration on endothelial dysfunction induced by post-methionine load hyperhomocysteinemia.

  1999cited by this paper
• Elevated Plasma Concentrations of Homocysteine in Antiepileptic Drug Treatment

  1999influential reference
• Risk of breast cancer in offspring of male breast-cancer patients.

  1999cited by this paper
• IMPLICATION OF FIBRATE THERAPY FOR HOMOCYSTEINE. AUTHORS' REPLY

  1999cited by this paper
• The C677T mutation in the methylenetetrahydrofolate reductase gene predisposes to hyperhomocysteinemia in children with familial hypercholesterolemia treated with cholestyramine.

  1998cited by this paper
• Oral contraceptives did not affect biochemical folate indexes and homocysteine concentrations in adolescent females.

  1998cited by this paper
• Metformin: Effects on CardiovascularRisk Factors in Patients withNon–Insulin-Dependent Diabetes Mellitus

  1998cited by this paper
• Effects of sex steroids on plasma total homocysteine levels: a study in transsexual males and females.

  1998cited by this paper
• The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study

  1998cited by this paper
• Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: implications for cardiovascular disease prevention.

  1998cited by this paper
• Plasma homocysteine concentrations are regulated by acute hyperinsulinemia in nondiabetic but not type 2 diabetic subjects.

  1998cited by this paper
• Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)

  1998cited by this paper
• Cardiovascular Outcomes in Type 2 Diabetes: A double-blind placebo-controlled study of bezafibrate: the St. Mary's, Ealing, Northwick Park Diabetes Cardiovascular Disease Prevention (SENDCAP) Study

  1998cited by this paper
• No change in impaired endothelial function after long-term folic acid therapy of hyperhomocysteinaemia in haemodialysis patients.

  1998cited by this paper
• Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat.

  1998cited by this paper
• Metformin: effects on cardiovascular risk factors in patients with non-insulin-dependent diabetes mellitus.

  1998cited by this paper
• Mechanism for reduction of serum folate by antiepileptic drugs during prolonged therapy.

  1997cited by this paper
• Metformin increases total serum homocysteine levels in non-diabetic male patients with coronary heart disease.

  1997cited by this paper
• Correlation between plasma homocyst(e)ine and aortic atherosclerosis.

  1997cited by this paper
• Vitamin B-6 normalizes the altered sulfur amino acid status of rats fed diets containing pharmacological levels of niacin without reducing niacin's hypolipidemic effects.

  1997cited by this paper
• Plasma total homocysteine concentrations in epileptic patients taking anticonvulsants.

  1997cited by this paper
• Vitamin Status and Hyperhomocysteinemia in a Healthy Population

  1997cited by this paper
• Abnormal homocysteine metabolism in rheumatoid arthritis.

  1997cited by this paper
• Treatment of Mild Hyperhomocysteinemia

  1997cited by this paper
• Plasma homocysteine levels and mortality in patients with coronary artery disease.

  1997cited by this paper
• Cardiovascular morbidity and mortality in patients with seropositive rheumatoid arthritis in Northern Sweden.

  1997cited by this paper
• Association between plasma homocysteine and extracranial carotid arterial disease in older persons.

  1997cited by this paper
• The effect of supraphysiologic doses of testosterone on fasting total homocysteine levels in normal men.

  1997cited by this paper
• Poor metabolic control, early age at onset, and marginal folate deficiency are associated with increasing levels of plasma homocysteine in insulin-dependent diabetes mellitus. A five-year follow-up study.

  1997cited by this paper
• Homocysteine Metabolism: From Basic Science to Clinical Medicine

  1997cited by this paper
• Hyperhomocysteinemia following a methionine load in patients with non-insulin-dependent diabetes mellitus and macrovascular disease.

  1996cited by this paper
• Homocysteine and cardiovascular disease

  1996cited by this paper
• The Effects of High- and Medium-Dose Metformin Therapy on Cardiovascular Risk Factors in Patients With Type II Diabetes

  1996cited by this paper
• The Effect of Metformin on the Metabolic Abnormalities Associated With Upper-Body Fat Distribution. BIGPRO Study Group

  1996cited by this paper
• Homocysteine and coronary atherosclerosis.

  1996cited by this paper
• Cardiovascular mortality in women with rheumatoid arthritis.

  1995cited by this paper
• Premature senescence and burden of life--lessons from the rheumatic diseases.

  1995cited by this paper
• Hyperhomocysteinaemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease

  1995cited by this paper
• Plasma homocysteine and menopausal status **

  1995cited by this paper
• A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes.

  1995influential reference
• Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis.

  1995cited by this paper
• Post-methionine load hyperhomocysteinemia in persons with normal fasting total plasma homocysteine: initial results from the NHLBI Family Heart Study.

  1995cited by this paper
• Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

  1994cited by this paper
• Vitamin requirements for the treatment of hyperhomocysteinemia in humans.

  1994cited by this paper
• Treatment of mild hyperhomocysteinemia in vascular disease patients.

  1994cited by this paper
• Efficacy of gemfibrozil in dyslipidaemic subjects with suspected heart disease. An ancillary study in the Helsinki Heart Study frame population.

  1993cited by this paper
• Decreased serum homocysteine in pregnancy.

  1992cited by this paper
• The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.

  1992cited by this paper
• Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease. Effects of pyridoxine and folic acid treatment.

  1990influential reference
• Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease.

  1985cited by this paper
• Affinity of cystathionine beta-synthase for pyridoxal 5'-phosphate in cultured cells. A mechanism for pyridoxine-responsive homocystinuria.

  1980cited by this paper
• Depression of the Intestinal Uptake of Radio–vitamin B12 by Cholestyramine 1

  1973cited by this paper
• PYRIDOXINE THERAPY IN HOMOCYSTINURIA

  1967cited by this paper

• The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo

  2025cites this paper
• Serum homocysteine-based traffic light triage colonoscopy screening in colorectal cancer at-risk patients: A prospective cohort study

  2025cites this paper
• Accelerated Brain Aging, Atherogenicity, and Neurocognition in Adult Survivors of Childhood Cancer

  2025cites this paper
• 5,10-methylenetetrahydrofolate reductase C677T gene polymorphism as a risk factor for premature coronary artery disease in patients with type 2 diabetes mellitus

  2025cites this paper
• Microbially catalyzed anode and cathode microbial electrosynthesis system for efficient metformin removal and volatile fatty acid production

  2024cites this paper
• Untargeted metabolic profiling of high-dose methotrexate toxicity shows alteration in betaine metabolism

  2024cites this paper
• Ferulic Acid Ameliorates L-Methionine-Induced Hyperhomocysteinemia in Rats

  2024cites this paper
• A micronutrient supplement modulates homocysteine levels regardless of vitamin B biostatus in elderly subjects.

  2023cites this paper
• Hyperhomocysteinemia: its impact on cardiovascular disease and atherosclerosis

  2023cites this paper
• Functional vitamin B12 deficiency is a consistent feature in hospital admissions for neurological disorders due to the use of nitrous oxide

  2023cites this paper
• The use of glucarpidase as a rescue therapy for high dose methotrexate toxicity – a review of pharmacological and clinical data

  2023cites this paper
• Non-Conventional Risk Factors: “Fact” or “Fake” in Cardiovascular Disease Prevention?

  2023cites this paper
• Homocysteine serum levels correlate with the number of failed IVF cycles even when within normal range

  2023cites this paper
• Hyperhomocysteinemia in Patients with Newly Diagnosed Primary Hypertension in Can Tho City, Vietnam

  2023cites this paper
• Hyperhomocysteinemia in acute hepatic porphyria (AHP) and implications for treatment with givosiran

  2022cites this paper
• Melissa Officinalis L. aqueous extract pretreatment decreases methotrexate-induced hepatotoxicity at lower dose and increases ^99mTc-phytate liver uptake, as a probe of liver toxicity assessment, in rats

  2022cites this paper
• Prevalence of homocysteinemia and effect of vitamin supplementation in retinal vein occlusion

  2022cites this paper
• Overview of Methotrexate Toxicity: A Comprehensive Literature Review

  2022cites this paper
• Effect of Blood Homocysteine on the Outcome of Artificial Insemination in Women with Polycystic Ovary Syndrome

  2022cites this paper
• Homocysteine, Vitamins B6 and Folic Acid in Experimental Models of Myocardial Infarction and Heart Failure—How Strong Is That Link?

  2022cites this paper
• Stereological and Biochemical Effects of Curcumin on the l-Methionine-Induced Cardiotoxicity in Rats

  2021cites this paper
• Hyperhomocysteinemia and Cancer: The Role of Natural Products and Nutritional Interventions

  2021cites this paper
• Melatonin as a Reducer of Neuro- and Vasculotoxic Oxidative Stress Induced by Homocysteine

  2021cites this paper
• Heart failure in patients with high homocysteine levels

  2021cites this paper
• A Concurrent Ischemic Stroke, Myocardial Infarction, and Aortic Thrombi in a Young Patient with Hyperhomocysteinemia: A Case Report

  2020cites this paper
• Homocysteine and age-associated disorders.

  2019cites this paper
• A novel approach in the management of hyperhomocysteinemia.

  2019cites this paper
• Targeting MTHFR for the treatment of migraines

  2018cites this paper
• Homocysteine: a new diagnostic marker in spontaneous bacterial peritonitis

  2018cites this paper
• Medicines associated with folate–homocysteine–methionine pathway disruption

  2018cites this paper
• Emodin Rescued Hyperhomocysteinemia-Induced Dementia and Alzheimer’s Disease-Like Features in Rats

  2018cites this paper
• Side effects of methotrexate therapy for rheumatoid arthritis: A systematic review.

  2018cites this paper
• Foetoplacental epigenetic changes associated with maternal metabolic dysfunction.

  2018cites this paper
• Nutritional Deficiencies in Pregnancy After Surgery For Morbid Obesity

  2017cites this paper
• Vitamin B12 Deficiency in the Elderly

  2017cites this paper
• Homocystein: A new biochemical marker in livestock sector

  2017cites this paper
• The metabolism and significance of homocysteine in nutrition and health

  2017cites this paper
• Relationship between homocysteine and intraocular pressure in men and women

  2016cites this paper
• Vitamin B12 deficiency in the elderly: is it worth screening?

  2015cites this paper
• Testing for hyperhomocysteinemia in subjects with a history of thromboembolic events using HPLC technique.

  2013cites this paper
• Hyperhomocysteinaemia is associated with biochemical hyperandrogenaemia in women with reproductive age.

  2013cites this paper
• Serum Homocysteine Level in Type 2 Diabetes Mellitus with Peripheral Arterial Disease

  2013cites this paper
• Hepatotoxicity related to antirheumatic drugs

  2011cites this paper
• Nutrition and Cardiovascular Disease: Homocysteine

  2011cites this paper
• The Genetics of Thrombosis

  2010cites this paper
• INTERNATIONAL HEALTH NEWS

  2010cites this paper
• Homocysteine and arterial thrombosis: Challenge and opportunity

  2010cites this paper
• Antithrombotic drug therapy in cardiovascular disease

  2010cites this paper