Protein kinase C mediates peroxynitrite toxicity to oligodendrocytes.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Molecular and cellular neurosciences

• Publication date

  2011-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.mcn.2011.06.006PMID 21708260
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Protein kinase C: poised to signal.

  2010cited by this paper
• Redox Control of Protein Kinase C: Cell- and Disease-Specific Aspects

  2010influential reference
• ZFP191 is required by oligodendrocytes for CNS myelination.

  2010cited by this paper
• Neuroprotective versus tumorigenic protein kinase C activators.

  2009cited by this paper
• Protein kinase C regulation of neuronal zinc signaling mediates survival during preconditioning

  2009cited by this paper
• Small molecule inhibitors of PKCTheta as potential antiinflammatory therapeutics.

  2009cited by this paper
• PKC inhibitors: potential in T cell-dependent immune diseases.

  2009cited by this paper
• Oxidative and Inflammatory Pathways in Parkinson’s Disease

  2008cited by this paper
• Metallothionein redox biology in the cytoprotective and cytotoxic functions of zinc.

  2008cited by this paper
• Protein kinase Cε: function in neurons

  2008cited by this paper
• Structural basis of protein kinase C isoform function.

  2008cited by this paper
• Protein kinase C theta (PKCtheta): a key player in T cell life and death.

  2007cited by this paper
• Protein Kinase C ζ

  2007cited by this paper
• Protein kinase C theta (PKCθ) : A key player in T cell life and death

  2007cited by this paper
• Nitric oxide and peroxynitrite in health and disease.

  2007cited by this paper
• Protein kinase C as a stress sensor.

  2007cited by this paper
• Intracellular Zinc Release, 12-Lipoxygenase Activation and MAPK Dependent Neuronal and Oligodendroglial Death

  2007cited by this paper
• Intracellular Zinc Release and ERK Phosphorylation Are Required Upstream of 12-Lipoxygenase Activation in Peroxynitrite Toxicity to Mature Rat Oligodendrocytes*

  2006cited by this paper
• Inflammation in white matter: clinical and pathophysiological aspects.

  2006cited by this paper
• Resistance to Experimental Autoimmune Encephalomyelitis and Impaired IL-17 Production in Protein Kinase Cθ-Deficient Mice

  2006cited by this paper
• Imbalance between pro-oxidant and pro-antioxidant functions of zinc in disease

  2005cited by this paper
• Protein kinase Ctheta controls Th1 cells in experimental autoimmune encephalomyelitis.

  2005cited by this paper
• Protein Kinase Cθ Controls Th1 Cells in Experimental Autoimmune Encephalomyelitis1

  2005cited by this paper
• Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes.

  2005cited by this paper
• Nitric oxide‐induced cell death in developing oligodendrocytes is associated with mitochondrial dysfunction and apoptosis‐inducing factor translocation

  2004cited by this paper
• 12‐Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes

  2004cited by this paper
• Caspase‐1 and poly (ADP‐ribose) polymerase inhibitors may protect against peroxynitrite‐induced neurotoxicity independent of their enzyme inhibitor activity

  2004cited by this paper
• Recovery of gap junctional intercellular communication after phorbol ester treatment requires proteasomal degradation of protein kinase C.

  2003cited by this paper
• Opposing roles of δ and εPKC in cardiac ischemia and reperfusion: targeting the apoptotic machinery

  2003cited by this paper
• Role of Proteolytic Activation of Protein Kinase Cδ in Oxidative Stress-Induced Apoptosis

  2003cited by this paper
• A novel role of protein kinase C-δ in cell signaling triggered by glutathione depletion

  2003cited by this paper
• Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm.

  2003influential reference
• A novel role of protein kinase C-delta in cell signaling triggered by glutathione depletion.

  2003cited by this paper
• Opposing roles of delta and epsilonPKC in cardiac ischemia and reperfusion: targeting the apoptotic machinery.

  2003cited by this paper
• Peroxynitrite Mediates Neurotoxicity of Amyloid β-Peptide1–42- and Lipopolysaccharide-Activated Microglia

  2002cited by this paper
• Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine and S‐nitrosothiols and with changes in glutathione levels

  2002cited by this paper
• Targeting of protein kinase C delta to mitochondria in the oxidative stress response.

  2001cited by this paper
• Zinc and disease of the brain

  2001cited by this paper
• Multiple pathways control protein kinase C phosphorylation

  2000cited by this paper
• Protein kinase C signaling and oxidative stress.

  2000cited by this paper
• A new Alamar Blue viability assay to rapidly quantify oligodendrocyte death.

  1999cited by this paper
• Mediation by Membrane Protein Kinase C of Zinc‐Induced Oxidative Neuronal Injury in Mouse Cortical Cultures

  1999cited by this paper
• Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development.

  1999cited by this paper
• Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly.

  1996cited by this paper
• The expression of myristoylated alanine-rich C-kinase substrate in oligodendrocytes is developmentally regulated.

  1995cited by this paper
• Developmental expression of protein kinase C isozymes in oligodendrocytes and their differentail modulation by 4β‐phorbol‐12, 13‐dibutyrate

  1994cited by this paper
• Rottlerin, a novel protein kinase inhibitor.

  1994influential reference
• Protein kinase C activity modulates myelin gene expression in enriched oligodendrocytes

  1993cited by this paper
• Protein kinase C.

  1991cited by this paper

• White Matter in Crisis: Oligodendrocytes and the Pathophysiology of Multiple Sclerosis

  2025cites this paper
• Influence of hormones in multiple sclerosis: focus on the most important hormones

  2023cites this paper
• Establishment of an erythroid progenitor cell line capable of enucleation achieved with an inducible c-Myc vector

  2019cites this paper
• Micronutrients in autoimmune diseases: possible therapeutic benefits of zinc and vitamin D.

  2019cites this paper
• Pre-proof Micronutrients in autoimmune diseases : Possible therapeutic benefits of zinc and vitamin D

  2019cites this paper
• Potential molecular targets of peroxynitrite in mediating blood–brain barrier damage and haemorrhagic transformation in acute ischaemic stroke with delayed tissue plasminogen activator treatment

  2018cites this paper
• The Emerging Role of Zinc in the Pathogenesis of Multiple Sclerosis

  2017influential citation
• Insights in pathogenesis of multiple sclerosis: nitric oxide may induce mitochondrial dysfunction of oligodendrocytes

  2017cites this paper
• Efficacy of N-Acetylserotonin and Melatonin in the EAE Model of Multiple Sclerosis

  2016cites this paper
• Propofol restores TRPV1 sensitivity via a TRPA1-, nitric oxide synthase-dependent activation of PKCε

  2015cites this paper
• Zn2+‐induced ERK activation mediates PARP‐1‐dependent ischemic‐reoxygenation damage to oligodendrocytes

  2013cites this paper
• The NOX1/4 inhibitor GKT136901 as selective and direct scavenger of peroxynitrite.

  2013cites this paper
• Peroxynitrite alters GABAergic synaptic transmission in immature rat hippocampal slices.

  2013cites this paper
• Therapeutic potential of a novel cannabinoid agent CB52 in the mouse model of experimental autoimmune encephalomyelitis.

  2013cites this paper
• Cytosolic zinc accumulation contributes to excitotoxic oligodendroglial death

  2013influential citation
• Intracellular Zinc Liberation: A Trigger for Oxidative Stress-Induced Toxicity to Neurons and Neuroglia

  2012cites this paper