Geranylgeranylated proteins are involved in the regulation of myeloma cell growth.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Clinical Cancer Research

• Publication date

  2005-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 15701825
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The HMG-CoA reductase inhibitor simvastatin overcomes cell adhesion-mediated drug resistance in multiple myeloma by geranylgeranylation of Rho protein and activation of Rho kinase.

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• Downstream effectors of oncogenic ras in multiple myeloma cells.

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