Hierarchical Nanoassemblies-Assisted Combinational Delivery of Cytotoxic Protein and Antibiotic for Cancer Treatment.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Nano letters (Print)

• Publication date

  2018-03-16

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1021/acs.nanolett.7b04976PMID 29547698
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Selective in vivo metabolic cell-labeling-mediated cancer targeting.

  2017cited by this paper
• Recent progress in nanomedicine-based combination cancer therapy using a site-specific co-delivery strategy.

  2017cited by this paper
• Sequentially Responsive Shell‐Stacked Nanoparticles for Deep Penetration into Solid Tumors

  2017cited by this paper
• Tumor-Specific Multiple Stimuli-Activated Dendrimeric Nanoassemblies with Metabolic Blockade Surmount Chemotherapy Resistance.

  2017cited by this paper
• Doxycycline inhibits the cancer stem cell phenotype and epithelial-to-mesenchymal transition in breast cancer

  2017cited by this paper
• A Substrate-Selective Enzyme-Catalysis Assembly Strategy for Oligopeptide Hydrogel-Assisted Combinatorial Protein Delivery.

  2017cited by this paper
• Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots.

  2016cited by this paper
• Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

  2016cited by this paper
• Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.

  2016cited by this paper
• Cancer nanomedicine: progress, challenges and opportunities

  2016cited by this paper
• Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells

  2015cited by this paper
• The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment.

  2015cited by this paper
• Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease

  2015cited by this paper
• Hyaluronic acid-decorated dual responsive nanoparticles of Pluronic F127, PLGA, and chitosan for targeted co-delivery of doxorubicin and irinotecan to eliminate cancer stem-like cells.

  2015cited by this paper
• A Collaborative Assembly Strategy for Tumor-Targeted siRNA Delivery.

  2015cited by this paper
• Principles of nanoparticle design for overcoming biological barriers to drug delivery

  2015cited by this paper
• Reactive oxygen species-responsive protein modification and its intracellular delivery for targeted cancer therapy.

  2014cited by this paper
• Combinatorially designed lipid-like nanoparticles for intracellular delivery of cytotoxic protein for cancer therapy.

  2014cited by this paper
• Integration of Nanoassembly Functions for an Effective Delivery Cascade for Cancer Drugs

  2014cited by this paper
• ATP-triggered anticancer drug delivery

  2014cited by this paper
• Clickable protein nanocapsules for targeted delivery of recombinant p53 protein.

  2014cited by this paper
• Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma.

  2013cited by this paper
• Photoswitchable nanoparticles for in vivo cancer chemotherapy

  2013cited by this paper
• Gene transfection efficacy and biocompatibility of polycation/DNA complexes coated with enzyme degradable PEGylated hyaluronic acid.

  2013cited by this paper
• Stimuli-responsive nanocarriers for drug delivery.

  2013cited by this paper
• Size-dependent localization and penetration of ultrasmall gold nanoparticles in cancer cells, multicellular spheroids, and tumors in vivo.

  2012cited by this paper
• Photoswitchable Nanoparticles for Triggered Tissue Penetration and Drug Delivery

  2012cited by this paper
• The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

  2012cited by this paper
• Antibody therapy of cancer

  2012cited by this paper
• The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles.

  2012cited by this paper
• Tailoring nanocarriers for intracellular protein delivery.

  2011cited by this paper
• PROVENGE (Sipuleucel-T) in Prostate Cancer: The First FDA-Approved Therapeutic Cancer Vaccine

  2011cited by this paper
• HYAL1 overexpression is correlated with the malignant behavior of human breast cancer

  2011cited by this paper
• Smart nanocarrier based on PEGylated hyaluronic acid for cancer therapy.

  2011cited by this paper
• Surface charge affects cellular uptake and intracellular trafficking of chitosan-based nanoparticles.

  2011cited by this paper
• Multistage nanoparticle delivery system for deep penetration into tumor tissue

  2011cited by this paper
• Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size.

  2011cited by this paper
• The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse.

  2011cited by this paper
• Delivering nanomedicine to solid tumors

  2010cited by this paper
• Effect of surface properties on nanoparticle-cell interactions.

  2010cited by this paper
• A novel intracellular protein delivery platform based on single-protein nanocapsules.

  2010cited by this paper
• High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability

  2009cited by this paper
• Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

  2008cited by this paper
• The clinicopathologic and prognostic significance of CD44+/CD24(-/low) and CD44-/CD24+ tumor cells in invasive breast carcinomas.

  2008cited by this paper
• Ribonucleases as novel chemotherapeutics : the ranpirnase example.

  2008cited by this paper
• Protein therapeutics: a summary and pharmacological classification

  2008cited by this paper
• Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer.

  2007cited by this paper
• Beyond tumorigenesis: cancer stem cells in metastasis

  2007cited by this paper
• Renal clearance of quantum dots

  2007cited by this paper
• CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis

  2006cited by this paper
• Cancer stem cells.

  2006cited by this paper
• Nanocarriers: promising vehicle for bioactive drugs.

  2006cited by this paper
• Prospective identification of tumorigenic breast cancer cells

  2003cited by this paper
• In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells.

  2003cited by this paper
• Stem cells, cancer, and cancer stem cells

  2001cited by this paper
• Ribonuclease A.

  1998cited by this paper
• Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

  1997cited by this paper
• CD44 is the principal cell surface receptor for hyaluronate.

  1990cited by this paper

• Programmable hierarchical hydrogel dressing for sequential release of growth factor and DNase to accelerate diabetic wound healing.

  2025cites this paper
• Rational design of anticancer multidrug nanosystems and their adaptation for glioblastoma treatment.

  2025cites this paper
• Advances in nanocarriers for targeted drug delivery and controlled drug release.

  2025cites this paper
• Developing bioinspired delivery systems for enhanced tumor penetration of macromolecular drugs.

  2025cites this paper
• A region-confined PROTAC nanoplatform for spatiotemporally tunable protein degradation and enhanced cancer therapy

  2024cites this paper
• Core-shell vector-mediated co-delivery of CRISPR/Cas9 system and hydrophobic drugs against triple-negative breast cancer stem cells.

  2024cites this paper
• Bacterial nanotechnology as a paradigm in targeted cancer therapeutic delivery and immunotherapy

  2024cites this paper
• Recent progress in macromolecules: From current therapeutic strategies to theranostic applications

  2024cites this paper
• A multifunctional ‘golden cicada’ nanoplatform breaks the thermoresistance barrier to launch cascade augmented synergistic effects of photothermal/gene therapy

  2023cites this paper
• Reviewing particulate delivery systems loaded with repurposed tetracyclines - from micro to nanoparticles.

  2023cites this paper
• A pH‐Responsive Virus‐Like Particle as a Protein Cage for a Targeted Delivery

  2023cites this paper
• Nanomedicine strategies to counteract cancer stemness and chemoresistance

  2023cites this paper
• Nanomedicine Strategies for Targeting Tumor Stroma

  2023cites this paper
• Dynamically crosslinked nanocapsules for the efficient and serum-resistant cytosolic protein delivery

  2023cites this paper
• Design of Disintegrable Nanoassemblies to Release Multiple Small-Sized Nanoparticles.

  2023cites this paper
• Bioenzyme-based nanomedicines for enhanced cancer therapy

  2022cites this paper
• pH-responsive organic/inorganic hybrid nanocolloids for transcellular delivery of ribonucleolytic payloads toward targeted anti-glioma therapy.

  2022cites this paper
• Hydroxyethyl starch-folic acid conjugates stabilized theranostic nanoparticles for cancer therapy.

  2022cites this paper
• Surface-anchored tumor microenvironment-responsive protein nanogel-platelet system for cytosolic delivery of therapeutic protein in the post-surgical cancer treatment.

  2022cites this paper
• ROS-responsive polypeptides for intracellular protein delivery and CRISPR/Cas9 gene editing

  2022cites this paper
• Endocytosis‐Independent and Cancer‐Selective Cytosolic Protein Delivery via Reversible Tagging with LAT1 substrate

  2022cites this paper
• Bioengineered nanogels for cancer immunotherapy.

  2022cites this paper
• Charge-Reversible Pro-Ribonuclease Enveloped in Virus-like Synthetic Nanocapsules for Systemic Treatment of Intractable Glioma.

  2022cites this paper
• Novel design of multifunctional nanozymes based on tumor microenvironment for diagnosis and therapy.

  2022cites this paper
• Reactive oxygen species (ROS)-responsive size-reducible nanoassemblies for deeper atherosclerotic plaque penetration and enhanced macrophage-targeted drug delivery

  2022cites this paper
• Bi-Functional Gold Nanorod-Protein Conjugates with Biomimetic BSA@Folic Acid Corona for Improved Tumor Targeting and Intracellular Delivery of Therapeutic Proteins in Colon Cancer 3D Spheroids.

  2022cites this paper
• Combating Cancer Stem-Like Cell-Derived Resistance to Anticancer Protein by Liposome-Mediated Acclimatization Strategy.

  2022cites this paper
• Bioresponsive nanogels for protein delivery

  2022cites this paper
• Tailoring Hyperbranched Poly(β‐amino ester) as a Robust and Universal Platform for Cytosolic Protein Delivery

  2021cites this paper
• Strengths and Challenges of Secretory Ribonucleases as AntiTumor Agents

  2021cites this paper
• Co-delivery of proteins and small molecule drugs for mitochondria-targeted combination therapy.

  2021cites this paper
• Advances in Multiple Stimuli-Responsive Drug-Delivery Systems for Cancer Therapy

  2021cites this paper
• Protein-Based Nanomedicine for Therapeutic Benefits of Cancer.

  2021cites this paper
• Coordination-driven assembly of proteins and nucleic acids in a single architecture for carrier-free intracellular co-delivery

  2021cites this paper
• Nanotechnologies for Intracellular Protein Delivery: Recent Progress in Inorganic and Organic Nanocarriers

  2021cites this paper
• An antibody-like peptidic network for anti-angiogenesis.

  2021cites this paper
• Nanotechnologies for the delivery of biologicals: historical perspective and current landscape.

  2021cites this paper
• Engineering Amyloid Aggregation as a New Way to Eliminate Cancer Stem Cells by the Disruption of Iron Homeostasis.

  2021cites this paper
• Specific photothermal killing of cancer cells by RNase-conjugated glyco-gold nanoparticles

  2021cites this paper
• Tumor microenvironment and nanotherapeutics: intruding the tumor fort.

  2021cites this paper
• M2 macrophage microvesicle-inspired nanovehicles improve accessibility to cancer cells and cancer stem cells in tumors

  2021cites this paper
• Retooling Cancer Nanotherapeutics' Entry into Tumors to Alleviate Tumoral Hypoxia.

  2020cites this paper
• Boronic acid-engineered gold nanoparticles for cytosolic protein delivery.

  2020cites this paper
• Enzyme-instructed hybrid nanogel/nanofiber oligopeptide hydrogel for localized protein delivery

  2020cites this paper
• Bioresponsive prodrug nanogel-based polycondensate strategy deepens tumor penetration and potentiates oxidative stress

  2020cites this paper
• Targeted Delivery of DNA Framework-Encapsulated Native Therapeutic Protein into Cancer Cells.

  2020cites this paper
• Self-regulated hirudin delivery for anticoagulant therapy

  2020cites this paper
• GE11 Peptide-Installed Chimaeric Polymersomes Tailor-Made for High-Efficiency EGFR-Targeted Protein Therapy of Orthotopic Hepatocellular Carcinoma.

  2020cites this paper
• Collaborative assembly-mediated siRNA delivery for relieving inflammation-induced insulin resistance

  2020cites this paper
• Hypoxia-instructed pro-protein therapy assisted with self-catalyzed nanozymogen.

  2020cites this paper
• Protein-Based Artificial Nanosystems in Cancer Therapy.

  2020cites this paper
• Polysaccharide-Based Biomaterials for Protein Delivery

  2020cites this paper
• Mild Acid Responsive "Nanoenzyme Capsule" Remodeling of Tumor Microenvironment to Increase Tumor Penetration.

  2020cites this paper
• ATP-Charged Nanoclusters Enable Intracellular Protein Delivery and Activity Modulation for Cancer Theranostics

  2020cites this paper
• CD44-targeted vesicles encapsulating granzyme B as artificial killer cells for potent inhibition of human multiple myeloma in mice.

  2020cites this paper
• A Protein@Inorganic Nano-Dumpling System for High-Loading Protein Delivery with Activatable Fluorescence and Magnetic Resonance Bimodal Imaging Capabilities.

  2020cites this paper
• Specific, Surface-Driven, and High-Affinity Interactions of Fluorescent Hyaluronan with PEGylated Nanomaterials

  2020cites this paper
• Hypoxia-sensitive supramolecular nanogels for the cytosolic delivery of ribonuclease A as a breast cancer therapeutic.

  2020cites this paper
• Carboplatin prodrug conjugated Fe3O4 nanoparticles for magnetically targeted drug delivery in ovarian cancer cells.

  2019cites this paper
• Artificial intelligence in nanomedicine.

  2019cites this paper
• Transferrin-Functionalized Microemulsions Coloaded with Coix Seed Oil and Tripterine Deeply Penetrate To Improve Cervical Cancer Therapy.

  2019cites this paper
• Synthetic networks with tunable responsiveness, biodegradation, and molecular recognition for precision medicine applications

  2019cites this paper
• A genipin-crosslinked protein–polymer hybrid system for the intracellular delivery of ribonuclease A

  2019cites this paper
• AS1411 aptamer/hyaluronic acid-bifunctionalized microemulsion co-loading shikonin and docetaxel for enhanced anti-glioma therapy.

  2019cites this paper
• Sequentially Site-Specific Delivery of Apoptotic Protein and Tumor-Suppressor Gene for Combination Cancer Therapy.

  2019cites this paper
• Redox-Responsive Polymeric Nanocomplex for Delivery of Cytotoxic Protein and Chemotherapeutics.

  2019cites this paper
• Near-Infrared Light-Sensitive Nano Neuro-Immune Blocker (NNIB) Capsule Relieves Pain and Enhances the Innate Immune Response for Necrotizing Infection.

  2019cites this paper
• Polymers for cytosolic protein delivery.

  2019cites this paper
• Multifunctional Albumin-Stabilized Gold Nanoclusters for the Reduction of Cancer Stem Cells

  2019cites this paper
• Natural Polyphenols Augment Cytosolic Protein Delivery by a Functional Polymer

  2019cites this paper
• Efficient Intracellular Delivery of RNase A Using DNA Origami Carriers.

  2019cites this paper
• A Tf-modified tripterine-loaded coix seed oil microemulsion enhances anti-cervical cancer treatment

  2018cites this paper
• Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance.

  2018cites this paper
• Protein Nanotherapeutics as an Emerging Modality for Cancer Therapy

  2018cites this paper
• Redox- and pH-Sensitive Glycan (Polysialic Acid) Derivatives and F127 Mixed Micelles for Tumor-Targeted Drug Delivery.

  2018cites this paper
• Recent Advances in Anti-cancer Protein/Peptide Delivery.

  2018cites this paper
• Versatile functionalization of surface-tailorable polymer nanohydrogels for drug delivery systems.

  2018cites this paper