Endogenous IL-15 sustains recruitment of IL-2Rbeta and common gamma and IL-2-mediated chemokine production in normal and inflamed human gingival fibroblasts.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Immunology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 15470063
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential STAT3, STAT5, and NF-kappaB activation in human hematopoietic progenitors by endogenous interleukin-15: implications in the expression of functional molecules.

  2003cited by this paper
• Expression of IL-2 receptor beta and gamma chains by human gingival fibroblasts and up-regulation of adhesion to neutrophils in response to IL-2.

  2003cited by this paper
• Human Gingival CD14+ Fibroblasts Primed with Gamma Interferon Increase Production of Interleukin-8 in Response to Lipopolysaccharide through Up-Regulation of Membrane CD14 and MyD88 mRNA Expression

  2002cited by this paper
• Fibroblasts from Human Spleen Regulate NK Cell Differentiation from Blood CD34+ Progenitors Via Cell Surface IL-151

  2002cited by this paper
• IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells.

  2002cited by this paper
• Absence of Monocyte Chemoattractant Protein 1 in Mice Leads to Decreased Local Macrophage Recruitment and Antigen-Specific T Helper Cell Type 1 Immune Response in Experimental Autoimmune Encephalomyelitis

  2001cited by this paper
• Interleukin-18 regulates both Th1 and Th2 responses.

  2001cited by this paper
• Dermal fibroblasts sustain proliferation of activated T cells via membrane-bound interleukin-15 upon long-term stimulation with tumor necrosis factor-alpha.

  2001cited by this paper
• Functional IL-2 Receptor β (CD122) and γ (CD132) Chains Are Expressed by Fibroblast-Like Synoviocytes: Activation by IL-2 Stimulates Monocyte Chemoattractant Protein-1 Production1

  2001cited by this paper
• Phenotypic and functional change of cytokine‐activated neutrophils: inflammatory neutrophils are heterogeneous and enhance adaptive immune responses

  2001cited by this paper
• Involvement of T-lymphocytes in periodontal disease and in direct and indirect induction of bone resorption.

  2001cited by this paper
• Lipopolysaccharide-Stimulated or Granulocyte-Macrophage Colony-Stimulating Factor-Stimulated Monocytes Rapidly Express Biologically Active IL-15 on Their Cell Surface Independent of New Protein Synthesis1 2

  2001cited by this paper
• Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation.

  2001cited by this paper
• Proteolysis of Human Monocyte CD14 by Cysteine Proteinases (Gingipains) from Porphyromonas gingivalis Leading to Lipopolysaccharide Hyporesponsiveness1

  2000cited by this paper
• Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1

  2000cited by this paper
• Altered natural killer cell differentiation in CD34+ progenitors from Chronic Myeloid Leukemia patients

  2000cited by this paper
• Unusual interleukin-4 and -13 signaling in human normal and tumor lung fibroblasts

  2000cited by this paper
• Differential intracellular trafficking, secretion and endosomal localization of two IL‐15 isoforms

  1999cited by this paper
• Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15.

  1999cited by this paper
• The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens.

  1999cited by this paper
• Heterogeneous Expression and Release of CD14 by Human Gingival Fibroblasts: Characterization and CD14-Mediated Interleukin-8 Secretion in Response to Lipopolysaccharide

  1998cited by this paper
• Interleukin-15 Activates Proinflammatory and Antimicrobial Functions in Polymorphonuclear Cells

  1998cited by this paper
• Expression of two interleukin‐15 mRNA isoforms in human tumors does not correlate with secretion: role of different signal peptides

  1997cited by this paper
• Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides.

  1997cited by this paper
• Human chemokines: an update.

  1997cited by this paper
• Is fibroblast heterogeneity relevant to the health, diseases, and treatments of periodontal tissues?

  1997cited by this paper
• Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms.

  1997cited by this paper
• CD40 expression by gingival fibroblasts: correlation of phenotype with function.

  1997cited by this paper
• Identification of a novel interleukin-15 (IL-15) transcript isoform generated by alternative splicing in human small cell lung cancer cell lines.

  1996cited by this paper
• Human fibroblasts express functional IL-2 receptors formed by the IL-2R alpha- and beta-chain subunits: association of IL-2 binding with secretion of the monocyte chemoattractant protein-1.

  1996cited by this paper
• CD14-mediated signal pathway of Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts

  1996cited by this paper
• Autocrine secretion and the physiological concentration of cytokines.

  1996cited by this paper
• Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15.

  1995cited by this paper
• The gamma subunit of the interleukin-2 receptor is expressed in human monocytes and modulated by interleukin-2, interferon gamma, and transforming growth factor beta 1.

  1994cited by this paper
• The IL-2/IL-2 receptor system: a current overview.

  1993cited by this paper
• The IL-2 receptor present on human embryonic fibroblasts is functional in the absence of P64/IL-2R gamma chain.

  1993cited by this paper
• Expression of the interleukin-2 receptor on human fibroblasts and its biological significance.

  1992cited by this paper
• Induction of interleukin-1 and -6 in human gingival fibroblast cultures stimulated with Bacteroides lipopolysaccharides

  1991cited by this paper
• Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations.

  1990cited by this paper

• The Impact of a New Interleukin-2-Based Immunotherapy Candidate on Urothelial Cells to Support Use for Intravesical Drug Delivery

  2020cites this paper
• Interleukin-15 directly stimulates pro-oxidative gene expression in skeletal muscle in-vitro via a mechanism that requires interleukin-15 receptor alpha.

  2015cites this paper
• Severe combined immunodeficiency—an update

  2015cites this paper
• IL-15 Signaling in Skeletal Muscle: Implications in Modulation of PGC-1alpha and Mitochondrial Biogenesis

  2014cites this paper
• Severe Combined Immunodeficiences: New and Old Scenarios

  2012cites this paper
• γ Chain transducing element: a shared pathway between endocrine and immune system.

  2011cites this paper
• Retraction: Endogenous IL-15 Sustains Recruitment of IL-2Rβ and Common γ and IL-2-Mediated Chemokine Production in Normal and Inflamed Human Gingival Fibroblasts

  2009cites this paper
• Expression of interleukin-15 and its receptor on the surface of stimulated human umbilical vein endothelial cells

  2009cites this paper
• Signalling, inflammation and arthritis: Crossed signals: the role of interleukin-15 and -18 in autoimmunity.

  2008cites this paper
• Blockage of JAK/STAT signalling attenuates renal ischaemia-reperfusion injury in rat.

  2007cites this paper
• Histamine Amplifies Immune Response of Gingival Fibroblasts

  2007cites this paper
• Modeled Repetitive Motion Strain and Indirect Osteopathic Manipulative Techniques in Regulation of Human Fibroblast Proliferation and Interleukin Secretion

  2007cites this paper
• IL-15/IL-15 receptor biology: a guided tour through an expanding universe.

  2006cites this paper
• Anti‐Inflammatory Role of Interleukin‐15 in Crohn's Disease

  2005cites this paper
• IL-15: targeting CD8+ T cells for immunotherapy.

  2005cites this paper