AGAMOUS Controls GIANT KILLER, a Multifunctional Chromatin Modifier in Reproductive Organ Patterning and Differentiation

The floral, homeotic protein AGAMOUS coordinates multiple downstream genes through direct transcriptional regulation of the nuclear matrix attachment region binding protein GIANT KILLER.

• Publication year

  2009

• Venue

  PLoS Biology

• Publication date

  2009-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1371/journal.pbio.1000251PMID 19956801PMCID 2774341
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Target Genes of the MADS Transcription Factor SEPALLATA3: Integration of Developmental and Hormonal Pathways in the Arabidopsis Flower

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• Over-expression of an AT-hook gene, AHL22, delays flowering and inhibits the elongation of the hypocotyl in Arabidopsis thaliana

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• A timing mechanism for stem cell maintenance and differentiation in the Arabidopsis floral meristem.

  2009cited by this paper
• SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis

  2008cited by this paper
• The AT-hook-containing proteins SOB3/AHL29 and ESC/AHL27 are negative modulators of hypocotyl growth in Arabidopsis.

  2007cited by this paper
• Identification of a Bipartite Jasmonate-Responsive Promoter Element in the Catharanthus roseus ORCA3 Transcription Factor Gene That Interacts Specifically with AT-Hook DNA-Binding Proteins1[W]

  2007cited by this paper
• Overexpression of a chromatin architecture-controlling AT-hook protein extends leaf longevity and increases the post-harvest storage life of plants.

  2007cited by this paper
• AGF1, an AT-Hook Protein, Is Necessary for the Negative Feedback of AtGA3ox1 Encoding GA 3-Oxidase1[W]

  2007cited by this paper
• The Homeotic Protein AGAMOUS Controls Late Stamen Development by Regulating a Jasmonate Biosynthetic Gene in Arabidopsis[W]

  2007cited by this paper
• NUBBIN and JAGGED define stamen and carpel shape in Arabidopsis

  2006cited by this paper
• Specification of leaf polarity in Arabidopsis via the trans-acting siRNA pathway.

  2006cited by this paper
• The Arabidopsis Zinc Finger-Homeodomain Genes Encode Proteins with Unique Biochemical Properties That Are Coordinately Expressed during Floral Development1

  2006cited by this paper
• Regulation of AUXIN RESPONSE FACTOR3 by TAS3 ta-siRNA affects developmental timing and patterning in Arabidopsis.

  2006cited by this paper
• Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.

  2006cited by this paper
• SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation.

  2006cited by this paper
• Trans-acting siRNA-mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis

  2006cited by this paper
• Novel transcription factor Satb2 interacts with matrix attachment region DNA elements in a tissue‐specific manner and demonstrates cell‐type‐dependent expression in the developing mouse CNS

  2005cited by this paper
• Transcriptional program controlled by the floral homeotic gene AGAMOUS during early organogenesis

  2005cited by this paper
• Pivotal role of AtSUVH2 in heterochromatic histone methylation and gene silencing in Arabidopsis

  2005cited by this paper
• Auxin Response Factors Mediate Arabidopsis Organ Asymmetry via Modulation of KANADI Activityw⃞

  2005cited by this paper
• IL-13受体α2降低血吸虫病肉芽肿的炎症反应并延长宿主存活时间[英]/Mentink-Kane MM,Cheever AW，Thompson RW，et al//Proc Natl Acad Sci U S A

  2005cited by this paper
• Genome-Wide Analysis of Spatial Gene Expression in Arabidopsis Flowers

  2004cited by this paper
• The Arabidopsis JAGGED gene encodes a zinc finger protein that promotes leaf tissue development

  2004cited by this paper
• The homeotic protein AGAMOUS controls microsporogenesis by regulation of SPOROCYTELESS

  2004cited by this paper
• Characterization of Antirrhinum Petal Development and Identification of Target Genes of the Class B MADS Box Gene DEFICIENSw⃞

  2004cited by this paper
• The role of JAGGED in shaping lateral organs

  2004cited by this paper
• KNUCKLES (KNU) encodes a C2H2 zinc-finger protein that regulates development of basal pattern elements of the Arabidopsis gynoecium

  2004cited by this paper
• Identification of a novel plant MAR DNA binding protein localized on chromosomal surfaces

  2004influential reference
• Whorl-specific expression of the SUPERMAN gene of Arabidopsis is mediated by cis elements in the transcribed region.

  2003cited by this paper
• Global Identification of Target Genes Regulated by APETALA3 and PISTILLATA Floral Homeotic Gene Action Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.006353.

  2003cited by this paper
• Tissue-specific nuclear architecture and gene expession regulated by SATB1

  2003cited by this paper
• In silico prediction of scaffold/matrix attachment regions in large genomic sequences.

  2002influential reference
• Plants Compared to Animals: The Broadest Comparative Study of Development

  2002cited by this paper
• GATEWAY vectors for Agrobacterium-mediated plant transformation.

  2002cited by this paper
• SATB1 targets chromatin remodelling to regulate genes over long distances

  2002cited by this paper
• The DEFECTIVE IN ANTHER DEHISCENCE1 Gene Encodes a Novel Phospholipase A1 Catalyzing the Initial Step of Jasmonic Acid Biosynthesis, Which Synchronizes Pollen Maturation, Anther Dehiscence, and Flower Opening in Arabidopsis

  2001cited by this paper
• Molecular biology of HMGA proteins: hubs of nuclear function.

  2001cited by this paper
• Construct design for efficient, effective and high-throughput gene silencing in plants.

  2001cited by this paper
• LEUNIG has multiple functions in gynoecium development in Arabidopsis

  2000cited by this paper
• Activation tagging in Arabidopsis.

  2000cited by this paper
• pGreen: a versatile and flexible binary Ti vector for Agrobacterium-mediated plant transformation

  2000cited by this paper
• Auxin and ETTIN in Arabidopsis gynoecium morphogenesis.

  2000cited by this paper
• LEUNIG, a putative transcriptional corepressor that regulates AGAMOUS expression during flower development.

  2000cited by this paper
• The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development.

  2000cited by this paper
• SHATTERPROOF MADS-box genes control seed dispersal in Arabidopsis

  2000cited by this paper
• AHM1, a Novel Type of Nuclear Matrix–Localized, MAR Binding Protein with a Single AT Hook and a J Domain–Homologous Region

  2000cited by this paper
• Molecular analysis of NOZZLE, a gene involved in pattern formation and early sporogenesis during sex organ development in Arabidopsis thaliana.

  1999cited by this paper
• CRABS CLAW, a gene that regulates carpel and nectary development in Arabidopsis, encodes a novel protein with zinc finger and helix-loop-helix domains.

  1999cited by this paper
• CRABS CLAW and SPATULA, two Arabidopsis genes that control carpel development in parallel with AGAMOUS.

  1999cited by this paper
• The SPOROCYTELESS gene of Arabidopsis is required for initiation of sporogenesis and encodes a novel nuclear protein.

  1999cited by this paper
• A homolog of NO APICAL MERISTEM is an immediate target of the floral homeotic genes APETALA3/PISTILLATA.

  1998cited by this paper
• AT-hook motifs identified in a wide variety of DNA-binding proteins.

  1998cited by this paper
• Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.

  1998cited by this paper
• The development of apical embryonic pattern in Arabidopsis.

  1998cited by this paper
• ETTIN patterns the Arabidopsis floral meristem and reproductive organs.

  1997cited by this paper
• A serine/threonine protein kinase gene isolated by an in vivo binding procedure using the Arabidopsis floral homeotic gene product, AGAMOUS.

  1997cited by this paper
• SARs are cis DNA elements of chromosome dynamics: synthesis of a SAR repressor protein.

  1995cited by this paper
• Arabidopsis gynoecium structure in the wild and in ettin mutants.

  1995cited by this paper
• LEUNIG regulates AGAMOUS expression in Arabidopsis flowers.

  1995cited by this paper
• Chromatin domains and prediction of MAR sequences.

  1995cited by this paper
• Control of Arabidopsis flower and seed development by the homeotic gene APETALA2.

  1994cited by this paper
• Regulation of the arabidopsis floral homeotic gene APETALA1.

  1994cited by this paper
• Function and regulation of the Arabidopsis floral homeotic gene PISTILLATA.

  1994cited by this paper
• Nucleotide sequences recognized by the AGAMOUS MADS domain of Arabidopsis thaliana in vitro.

  1993cited by this paper
• Isolation and characterization of the binding sequences for the product of the Arabidopsis floral homeotic gene AGAMOUS.

  1993cited by this paper
• The homeotic gene APETALA3 of Arabidopsis thaliana encodes a MADS box and is expressed in petals and stamens.

  1992cited by this paper
• A versatile binary vector system with a T-DNA organisational structure conducive to efficient integration of cloned DNA into the plant genome

  1992cited by this paper
• Genetic interactions among floral homeotic genes of Arabidopsis.

  1991cited by this paper
• The war of the whorls: genetic interactions controlling flower development

  1991cited by this paper
• AGL1-AGL6, an Arabidopsis gene family with similarity to floral homeotic and transcription factor genes.

  1991cited by this paper
• The protein encoded by the Arabidopsis homeotic gene agamous resembles transcription factors

  1990cited by this paper
• Early flower development in Arabidopsis.

  1990cited by this paper
• The A.T-DNA-binding domain of mammalian high mobility group I chromosomal proteins. A novel peptide motif for recognizing DNA structure.

  1990cited by this paper
• Genes directing flower development in Arabidopsis.

  1989cited by this paper
• Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites.

  1986cited by this paper
• Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold.

  1984cited by this paper

• An AT-hook motif nuclear protein AHL13 interacts with Poly(ADP-ribose) to regulate Arabidopsis immunity.

  2026cites this paper
• AT-HOOK-MOTIF NUCLEAR LOCALIZED 15 extends plant longevity by binding at poorly accessible, epigenetic mark-depleted chromatin that surrounds transcribed regions

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• CsAHL20 negatively regulates epi-catechins biosynthesis under drought stress in Camellia sinensis.

  2025cites this paper
• AHL26, an AT-hook gene, negatively regulates hypocotyl growth and flowering time in Arabidopsis thaliana

  2025cites this paper
• Twenty years of AT-HOOK MOTIF NUCLEAR LOCALIZED (AHL) gene family research – their potential in crop improvement

  2025cites this paper
• AT-HOOK MOTIF NUCLEAR LOCALIZED transcription factors AHL19, AHL21 and AHL23 - the modulators of the root system development.

  2025cites this paper
• Arabidopsis response to the apocarotenoid zaxinone involves interference with strigolactone signaling via binding to DWARF14

  2025cites this paper
• The Role of CRABS CLAW Transcription Factor in Floral Organ Development in Plants

  2025cites this paper
• Genome-wide analysis of radish AHL gene family and functional verification of RsAHL14 in tomato

  2024cites this paper
• Molecular Mechanism of ARF5-AHL15-Mediated Auxin-Induced Embryogenic Cell Formation in Apples.

  2024cites this paper
• AT-hook motif nuclear localized transcription factors function redundantly in promoting root growth through modulation of redox homeostasis.

  2024cites this paper
• Overexpression of AHL proteins enhances root hair production by altering the transcription of RHD6‐downstream genes

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  2023cites this paper
• A model worker: Multifaceted modulation of AUXIN RESPONSE FACTOR3 orchestrates plant reproductive phases

  2023influential citation
• Identification of tomato AHL gene families and functional analysis their roles in fruit development and abiotic stress response.

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• A histone modi cation-based synthetic circuit to engineer temporal gene expression in Arabidopsis oral meristems

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• The effect of short-term activation of AHL15 on long-term plant developmental change and transcriptome profile

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  2020cites this paper
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• miR156‐independent repression of the ageing pathway by longevity‐promoting AHL proteins in Arabidopsis

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• Transcriptome and epigenome analyses of vernalization in Arabidopsis thaliana.

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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2011cites this paper
• MADS: the missing link between identity and growth?

  2011cites this paper
• Coordinate activation of inflammatory gene networks, alveolar destruction and neonatal death in AKNA deficient mice

  2011cites this paper
• Coordination of flower development by homeotic master regulators.

  2011cites this paper
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  2011cites this paper
• Shedding light on the role of AT-hook/PPC domain protein in Arabidopsis thaliana

  2010cites this paper
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  2010cites this paper