Hypoxia causes vasodilatation of coronary arteries which protects the heart from ischaemic damage through mechanisms including the generation of hydrogen sulphide (H2S), but the influence of the perivascular adipose tissue (PVAT) and myocardium is incompletely understood. This study aimed to determine whether PVAT and the myocardium modulate the coronary artery hypoxic response and whether this involves hydrogen sulphide.
Coronary artery hypoxic vasorelaxation is augmented by perivascular adipose tissue through a mechanism involving hydrogen sulphide and cystathionine‐β‐synthase
J. Donovan,P. S. Wong,M. Garle,Stephen P. H. Alexander,W. Dunn,V. Ralevic
Published 2018 in Acta Physiologica
ABSTRACT
PUBLICATION RECORD
- Publication year
2018
- Venue
Acta Physiologica
- Publication date
2018-07-11
- Fields of study
Biology, Medicine, Chemistry, Environmental Science
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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