Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: insights from molecular modeling studies.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Bioorganic & Medicinal Chemistry

• Publication date

  2007-08-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.BMC.2007.05.021PMID 17521909PMCID PMC1949415
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Impact of species-dependent differences on screening, design, and development of MAO B inhibitors.

  2006cited by this paper
• Synthesis and Molecular Modelling of Novel Substituted‐4,5‐dihydro‐(1H)‐pyrazole Derivatives as Potent and Highly Selective Monoamine Oxidase‐A Inhibitors

  2006cited by this paper
• The therapeutic potential of monoamine oxidase inhibitors

  2006cited by this paper
• Sulfur-substituted alpha-alkyl phenethylamines as selective and reversible MAO-A inhibitors: biological activities, CoMFA analysis, and active site modeling.

  2005cited by this paper
• Monoamine Oxidase Inhibition In the Light of New Structural Data

  2005cited by this paper
• Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B.

  2005cited by this paper
• Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis.

  2005cited by this paper
• Docking studies on monoamine oxidase-B inhibitors: estimation of inhibition constants (K(i)) of a series of experimentally tested compounds.

  2005cited by this paper
• Eugenol and its structural analogs inhibit monoamine oxidase A and exhibit antidepressant-like activity.

  2005cited by this paper
• Virtual screening of biogenic amine-binding G-protein coupled receptors: comparative evaluation of protein- and ligand-based virtual screening protocols.

  2005cited by this paper
• Heteroarylisopropylamines as MAO inhibitors.

  2005cited by this paper
• Structure of rat monoamine oxidase A and its specific recognitions for substrates and inhibitors.

  2004cited by this paper
• Monoamine oxidases: certainties and uncertainties.

  2004cited by this paper
• Structure and mechanism of monoamine oxidase.

  2004cited by this paper
• Chemical aspects of amine oxidation by flavoprotein enzymes.

  2004cited by this paper
• MAO inhibition by arylisopropylamines: the effect of oxygen substituents at the beta-position.

  2004cited by this paper
• Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues.

  2004cited by this paper
• A two-step method for the preparation of homochiral cathinones

  2003cited by this paper
• Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures

  2003cited by this paper
• Monoamine oxidase inhibitory properties of optical isomers and N-substituted derivatives of 4-methylthioamphetamine.

  2003cited by this paper
• Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders

  2002cited by this paper
• Charge-transfer interactions in the inhibition of MAO-A by phenylisopropylamines – a QSAR study

  2002cited by this paper
• Phentermine inhibition of recombinant human liver monoamine oxidases A and B.

  2002cited by this paper
• High-level expression of human liver monoamine oxidase A in Pichia pastoris: comparison with the enzyme expressed in Saccharomyces cerevisiae.

  2002cited by this paper
• Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT(2A/2C) receptor agonists.

  2001cited by this paper
• Evidence for alternative binding modes in the interaction of benzylamine analogues with bovine liver monoamine oxidase B.

  2000cited by this paper
• High-level expression of human liver monoamine oxidase B in Pichia pastoris.

  2000cited by this paper
• Structure-activity relations in the oxidation of phenethylamine analogues by recombinant human liver monoamine oxidase A.

  2000cited by this paper
• Structure-activity relationships in the oxidation of para-substituted benzylamine analogues by recombinant human liver monoamine oxidase A.

  1999cited by this paper
• Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

  1998cited by this paper
• Monoamine oxidase inhibitory properties of some methoxylated and alkylthio amphetamine derivatives: structure-activity relationships.

  1997cited by this paper
• Radical Ideas about Monoamine Oxidase

  1995cited by this paper
• A well-behaved electrostatic potential-based method using charge restraints for deriving atomic char

  1993cited by this paper
• What is computational chemistry?

  1987cited by this paper
• Stereoselectivity and isoenzyme selectivity of monoamine oxidase inhibitors. Enantiomers of amphetamine, N-methylamphetamine and deprenyl.

  1985cited by this paper
• Stereoselectivity and isoenzyme selectivity of monoamine oxidase inhibitors: Enantiomers of amphetamine, n-methylamphetamine and deprenyl

  1985cited by this paper
• Friedel-Crafts acylation with N-(trifluoroacetyl)-.alpha.-amino acid chlorides. Application to the preparation of .beta.-arylalkylamines and 3-substituted 1,2,3,4-tetrahydroisoquinolines

  1984cited by this paper
• Substrate‐ and stereoselective inhibition of human brain monoamine oxidase by 4‐dimethylamino‐α, 2‐dimethylphenethylamine (FLA 336)

  1981cited by this paper
• Substrate- and stereoselective inhibitor of human brain monoamine oxidase by 4-dimethylamino-alpha, 2-dimethylphenethylamine (FLA 336).

  1981cited by this paper
• Correction. Trifluoroacetylation of Amino Acids and Peptides by Ethyl Trifluoroacetate

  1979cited by this paper
• Selective monoamine oxidase inhibitors. 1. Compounds related to 4-aminophenethylamine.

  1978cited by this paper
• Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction.

  1973cited by this paper
• van der Waals Volumes and Radii

  1964cited by this paper

• Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions

  2022cites this paper
• Coumarin-Chalcone Hybrids as Inhibitors of MAO-B: Biological Activity and In Silico Studies

  2021cites this paper
• Amphetamine Derivatives as Monoamine Oxidase Inhibitors

  2020cites this paper
• Alkaloids of the Cactaceae — The Classics

  2019cites this paper
• Privileged scaffolds as MAO inhibitors: Retrospect and prospects.

  2018cites this paper
• 3D similarities between the binding sites of monoaminergic target proteins

  2018cites this paper
• 3D-QSAR and in-silico Studies of Natural Products and Related Derivatives as Monoamine Oxidase Inhibitors

  2018cites this paper
• Docking-Related Survey on Natural-Product-Based New Monoamine Oxidase Inhibitors and Their Therapeutic Potential.

  2017cites this paper
• Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

  2017cites this paper
• Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration

  2016cites this paper
• Synthesis, Biological Evaluation, and Molecular Simulation of Chalcones and Aurones as Selective MAO‐B Inhibitors

  2015cites this paper
• Similarities Between the Binding Sites of Monoamine Oxidase (MAO) from Different Species — Is Zebrafish a Useful Model for the Discovery of Novel MAO Inhibitors?

  2013influential citation
• Inhibitor design for monoamine oxidases.

  2013cites this paper
• Monoamine oxidase inhibitors: ten years of docking studies.

  2012cites this paper
• Monoamine oxidases: the biochemistry of the proteins as targets in medicinal chemistry and drug discovery.

  2012cites this paper
• Topological probes of monoamine oxidases A and B in rat liver mitochondria: inhibition by TEMPO-substituted pargyline analogues and inactivation by proteolysis.

  2011cites this paper
• Kinetic behavior and reversible inhibition of monoamine oxidases--enzymes that many want dead.

  2011cites this paper
• ²H kinetic isotope effects and pH dependence of catalysis as mechanistic probes of rat monoamine oxidase A: comparisons with the human enzyme.

  2011cites this paper
• Rational design, synthesis, molecular modeling and evaluation of -carboline and 5H-indeno[1,2-c]pyridazin-5-one derivatives as potential MAO and IDO inhibitors : Conception rationnelle, synthèse, modélisation moléculaire et évaluation de dérivés -carbolines et 5H-indéno[1,2-c]pyridazin-5-ones comme

  2011cites this paper
• 2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors.

  2010cites this paper
• High-level expression and purification of rat monoamine oxidase A (MAO A) in Pichia pastoris: comparison with human MAO A.

  2010cites this paper
• Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors.

  2009cites this paper
• Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors.

  2009cites this paper
• Analogues de sphingolipides synthétiques

  2008cites this paper
• Comparison of the structural properties of the active site cavities of human and rat monoamine oxidase A and B in their soluble and membrane-bound forms.

  2008cites this paper
• Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

  2008cites this paper