Systemic Adiponectin Malfunction as a Risk Factor for Cardiovascular Disease

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Antioxidants and Redox Signaling

• Publication date

  2011-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/ars.2010.3743PMID 21091079PMCID PMC3159112
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Recessive protective effect of ADIPOQ rs1501299 on cardiovascular diseases with type 2 diabetes: a meta-analysis.

  2012cited by this paper
• Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population.

  2012cited by this paper
• Risk Factors in Heart Disease: Therapeutic Interventions

  2011cited by this paper
• Reduced vascular responsiveness to adiponectin in hyperlipidemic rats--mechanisms and significance.

  2010cited by this paper
• Adiponectin in insulin resistance: lessons from translational research.

  2010cited by this paper
• Cardiomyocyte-derived adiponectin is biologically active in protecting against myocardial ischemia-reperfusion injury.

  2010cited by this paper
• Cardioprotective effect of adiponectin is partially mediated by its AMPK-independent antinitrative action.

  2009cited by this paper
• Protective vascular and myocardial effects of adiponectin

  2009cited by this paper
• Adiponectin Promotes Revascularization of Ischemic Muscle through a Cyclooxygenase 2-Dependent Mechanism

  2009cited by this paper
• Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats.

  2009cited by this paper
• Endothelial dysfunction in adiponectin deficiency and its mechanisms involved.

  2009cited by this paper
• AMP-Activated Protein Kinase Deficiency Enhances Myocardial Ischemia/Reperfusion Injury but Has Minimal Effect on the Antioxidant/Antinitrative Protection of Adiponectin

  2009cited by this paper
• Changes in adiponectin, its receptors and AMPK activity in tissues of diet-induced diabetic mice.

  2008cited by this paper
• Leptin, ghrelin, and adiponectin evaluation in transsexual subjects during hormonal treatments.

  2008cited by this paper
• Adiponectin Protects Against Angiotensin II or Tumor Necrosis Factor &agr;–Induced Endothelial Cell Monolayer Hyperpermeability: Role of cAMP/PKA Signaling

  2008cited by this paper
• Cyclooxygenase‐2 induction by adiponectin is regulated by a sphingosine kinase‐1 dependent mechanism in cardiac myocytes

  2008cited by this paper
• High molecular weight adiponectin activates AMPK and suppresses cytokine‐induced NF‐κB activation in vascular endothelial cells

  2008cited by this paper
• Usefulness of adiponectin to predict myocardial salvage following successful reperfusion in patients with acute myocardial infarction.

  2008cited by this paper
• Adiponectin protects against myocardial ischaemia-reperfusion injury via AMP-activated protein kinase, Akt, and nitric oxide.

  2008cited by this paper
• Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo.

  2007cited by this paper
• Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity.

  2007cited by this paper
• The ischemic heart: starving to stimulate the adiponectin-AMPK signaling axis.

  2007cited by this paper
• Metabolic Syndrome and Cardiovascular Disease: Challenges and Opportunities

  2007cited by this paper
• Globular adiponectin resistance develops independently of impaired insulin-stimulated glucose transport in soleus muscle from high-fat-fed rats.

  2007cited by this paper
• Serum adiponectin is a predictor of coronary heart disease: a population-based 10-year follow-up study in elderly men.

  2007cited by this paper
• Adiponectin Cardioprotection After Myocardial Ischemia/Reperfusion Involves the Reduction of Oxidative/Nitrative Stress

  2007influential reference
• Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies.

  2007cited by this paper
• Cardioprotective Effects of Short-Term Caloric Restriction Are Mediated by Adiponectin via Activation of AMP-Activated Protein Kinase

  2007cited by this paper
• Adipokines and vascular disease in diabetes

  2007cited by this paper
• Adiponectin suppresses IkappaB kinase activation induced by tumor necrosis factor-alpha or high glucose in endothelial cells: role of cAMP and AMP kinase signaling.

  2007cited by this paper
• Adiponectin suppresses IκB kinase activation induced by tumor necrosis factor-α or high glucose in endothelial cells: role of cAMP and AMP kinase signaling

  2007cited by this paper
• Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.

  2006cited by this paper
• Mechanisms regulating energy metabolism by adiponectin in obesity and diabetes.

  2006cited by this paper
• Testosterone decreases adiponectin levels in female to male transsexuals.

  2006cited by this paper
• Adiponectin Suppression of High-Glucose–Induced Reactive Oxygen Species in Vascular Endothelial Cells

  2006cited by this paper
• The metabolic syndrome and endothelial dysfunction: Common highway to type 2 diabetes and CVD?

  2006cited by this paper
• The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects.

  2005cited by this paper
• Stimulated HSP90 binding to eNOS and activation of the PI3-Akt pathway contribute to globular adiponectin-induced NO production: vasorelaxation in response to globular adiponectin.

  2005cited by this paper
• Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms

  2005influential reference
• corrigendum: Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

  2004cited by this paper
• Plasma adiponectin levels and risk of myocardial infarction in men.

  2004cited by this paper
• Adiponectin Stimulates Angiogenesis by Promoting Cross-talk between AMP-activated Protein Kinase and Akt Signaling in Endothelial Cells*

  2004cited by this paper
• Selective Suppression of Endothelial Cell Apoptosis by the High Molecular Weight Form of Adiponectin

  2004cited by this paper
• Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity*

  2004cited by this paper
• Hypoadiponectinaemia in South Asian women during pregnancy: evidence of ethnic variation in adiponectin concentration

  2004cited by this paper
• Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilation.

  2004cited by this paper
• T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin.

  2004cited by this paper
• Adiponectin Stimulates Angiogenesis in Response to Tissue Ischemia through Stimulation of AMP-activated Protein Kinase Signaling*

  2004cited by this paper
• Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels.

  2004cited by this paper
• Ethnic differences in adiponectin levels.

  2004cited by this paper
• Circulating adiponectin levels increase in rats on caloric restriction: the potential for insulin sensitization.

  2004cited by this paper
• Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex

  2003cited by this paper
• Lower serum adiponectin levels in African-American boys.

  2003cited by this paper
• Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

  2003cited by this paper
• Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha.

  2003cited by this paper
• Globular adiponectin upregulates nitric oxide production in vascular endothelial cells

  2003cited by this paper
• Association of Hypoadiponectinemia With Impaired Vasoreactivity

  2003cited by this paper
• Association of Hypoadiponectinemia With Coronary Artery Disease in Men

  2003cited by this paper
• Adiponectin Stimulates Production of Nitric Oxide in Vascular Endothelial Cells*

  2003influential reference
• Erratum

  2003cited by this paper
• Hypoadiponectinemia is closely linked to endothelial dysfunction in man.

  2003cited by this paper
• Impaired Multimerization of Human Adiponectin Mutants Associated with Diabetes

  2003cited by this paper
• Myogenic Akt Signaling Regulates Blood Vessel Recruitment during Myofiber Growth

  2002cited by this paper
• Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell

  2002cited by this paper
• Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.

  2002cited by this paper
• Disruption of Adiponectin Causes Insulin Resistance and Neointimal Formation*

  2002cited by this paper
• Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

  2002cited by this paper
• Novel modulator for endothelial adhesion molecules : Adipocyte-derived plasma protein adiponectin

  2001cited by this paper
• The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

  2001cited by this paper
• The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

  2001cited by this paper
• Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages

  2001cited by this paper
• Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages

  2001cited by this paper
• Inconsistent relation of MAPK activation to infarct size reduction by ischemic preconditioning in pigs.

  2000cited by this paper
• 5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase.

  2000cited by this paper
• Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

  2000cited by this paper
• Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages.

  2000cited by this paper
• Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-&kgr;B Signaling Through a cAMP-Dependent Pathway

  2000influential reference
• Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity.

  1999cited by this paper
• Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin.

  1999cited by this paper
• Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma.

  1996cited by this paper
• AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity (*)

  1996cited by this paper
• cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1).

  1996cited by this paper
• A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes (*)

  1995influential reference

• Adiponectin Resistance in Obesity: Adiponectin Leptin/Insulin Interaction.

  2024cites this paper
• Serum Adiponectin Levels Increase in Acute Ischemic Stroke and Correlate with Patients’ Outcomes: A Pilot Study

  2024cites this paper
• Nitrative Modification of Caveolin-3: A Novel Mechanism of Cardiac Insulin Resistance and a Potential Therapeutic Target Against Ischemic Heart Failure in Prediabetic Animals

  2023cites this paper
• Relationship between chronic obstructive pulmonary disease and adiponectin concentrations: An updated meta-analysis and single-cell RNA sequencing

  2023cites this paper
• Diminished AdipoR1/APPL1 Interaction Mediates Reduced Cardioprotective Actions of Adiponectin against Myocardial Ischemia/Reperfusion Injury in Type-2 Diabetic Mice

  2023cites this paper
• Multifactorial Aspects of Adiponectin in Non- Alcoholic Fatty Liver Disease

  2023cites this paper
• “Know Diabetes by Heart”: role of adipocyte-cardiomyocyte communications

  2021cites this paper
• Adiponectin: Structure, Physiological Functions, Role in Diseases, and Effects of Nutrition

  2021cites this paper
• Increased urinary adiponectin level is associated with contrast-induced nephropathy in patients undergoing elective percutaneous coronary intervention

  2019cites this paper
• Adiponectin-Resistance in Obesity.

  2017cites this paper
• A Comprehensive Survey of the Roles of Highly Disordered Proteins in Type 2 Diabetes

  2017influential citation
• Cardioprotection of ischemic preconditioning in rats involves upregulating adiponectin.

  2017cites this paper
• Sex differences in the regulation of porcine coronary artery tone by perivascular adipose tissue: a role of adiponectin?

  2017cites this paper
• Intrinsic disorder in biomarkers of insulin resistance, hypoadiponectinemia, and endothelial dysfunction among the type 2 diabetic patients

  2016influential citation
• Changes in Plasma Adiponectin Concentrations in Patients With Hemorrhagic Fever With Renal Syndrome

  2016cites this paper
• Adiponectin resistance in skeletal muscle: pathophysiological implications in chronic heart failure

  2015cites this paper
• TNF-α antagonism ameliorates myocardial ischemia-reperfusion injury in mice by upregulating adiponectin.

  2015cites this paper
• OMEGA-3 FATTY ACIDS/VITAMIN E BEHAVE SYNERGISTICALLY ON ADIPONECTIN RECEPTOR-1 AND ADIPONECTIN RECEPTOR-2 GENE EXPRESSIONS IN PERIPHERAL BLOOD MONONUCLEAR CELL OF CORONARY ARTERY DISEASE PATIENTS

  2015cites this paper
• Adipokines: Leptin and Adiponectin in the Regulation of Inflammatory and Immune Responses

  2014cites this paper
• Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice.

  2014cites this paper
• Impaired Adiponectin Signaling Contributes to Disturbed Catabolism of Branched-Chain Amino Acids in Diabetic Mice

  2014cites this paper
• Effect of monomeric adiponectin on cardiac function and perfusion in anesthetized pig.

  2014influential citation
• Longitudinal changes in the relationship between serum adiponectin concentration and cardiovascular risk factors among apparently healthy middle-aged adults.

  2013cites this paper
• Association Between Epicardial Fat Thickness and Weight Homeostasis Hormones in Patients With Noncachectic Heart Failure

  2013cites this paper
• Interplay between adipose tissue and blood vessels in obesity and vascular dysfunction

  2013cites this paper
• Reduced high‐molecular‐weight adiponectin is an independent risk factor for cardiovascular lesions in hypercholesterolaemic patients

  2013cites this paper
• Protective effects of a novel trimerized sTNFRII on acute liver injury.

  2012cites this paper
• Adiponectin and adipocyte fatty acid binding protein in the pathogenesis of cardiovascular disease.

  2012cites this paper
• Adiponectina, obesidad y síndrome metabólico: una relación para profundizar

  2012cites this paper
• Pathophysiological Insights into Cardiovascular Health in Metabolic Syndrome

  2012cites this paper
• Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population.

  2012cites this paper
• Recessive protective effect of ADIPOQ rs1501299 on cardiovascular diseases with type 2 diabetes: a meta-analysis.

  2012cites this paper
• Adiponectin Action: A Combination of Endocrine and Autocrine/Paracrine Effects

  2011cites this paper
• Functional Adiponectin Resistance and Exercise Intolerance in Heart Failure

  2011cites this paper
• Untersuchungen zur Rolle der Lipoxygenase und der Interaktion des epikardialen Fetts mit dem herzen im Menschen und im Tiermodell

  2011cites this paper
• Cardiac Insulin Resistance and MicroRNA Modulators

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• Risk Factors in Heart Disease: Therapeutic Interventions

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