The Effects of Cannabidiol (CBD) on &Dgr;9-Tetrahydrocannabinol (THC) Self-Administration in Male and Female Long-Evans Rats

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Experimental and clinical psychopharmacology

• Publication date

  2017-07-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1037/pha0000135PMID 28682102
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• An assessment of sex differences in &Dgr;9‐tetrahydrocannabinol (THC) taste and place conditioning

  2017cited by this paper
• Delta-9-tetrahydrocannabinol (THC) history fails to affect THC's ability to induce place preferences in rats.

  2016cited by this paper
• Oral Cannabidiol does not Alter the Subjective, Reinforcing or Cardiovascular Effects of Smoked Cannabis

  2016cited by this paper
• Sex Differences in Animal Models: Focus on Addiction

  2016cited by this paper
• Cannabidiol fails to reverse hypothermia or locomotor suppression induced by Δ9‐tetrahydrocannabinol in Sprague‐Dawley rats

  2015cited by this paper
• Adolescent nicotine exposure fails to impact cocaine reward, aversion and self-administration in adult male rats.

  2015cited by this paper
• Comparative risk assessment of alcohol, tobacco, cannabis and other illicit drugs using the margin of exposure approach

  2015cited by this paper
• Neural correlates of interactions between cannabidiol and Δ9‐tetrahydrocannabinol in mice: implications for medical cannabis

  2015cited by this paper
• Conditioned taste avoidance induced by Δ(9)-tetrahydrocannabinol in the Fischer (F344) and Lewis (LEW) rat strains.

  2014cited by this paper
• The Global Burden of Disease projects: what have we learned about illicit drug use and dependence and their contribution to the global burden of disease?

  2014cited by this paper
• Evaluation of WIN 55,212-2 self-administration in rats as a potential cannabinoid abuse liability model.

  2014cited by this paper
• The Global Epidemiology and Contribution of Cannabis Use and Dependence to the Global Burden of Disease: Results from the GBD 2010 Study

  2013cited by this paper
• Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment

  2013cited by this paper
• Cannabidiol potentiates Δ9-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats

  2011cited by this paper
• Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology

  2010cited by this paper
• Cannabis use disorder: Epidemiology and management

  2009cited by this paper
• Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol.

  2008cited by this paper
• Cannabinoid self‐administration in rats: sex differences and the influence of ovarian function

  2007cited by this paper
• Previous Exposure to Cocaine Enhances Cocaine Self-Administration in an Alpha 1-Adrenergic Receptor Dependent Manner

  2007cited by this paper
• Strain and schedule-dependent differences in the acquisition, maintenance and extinction of intravenous cannabinoid self-administration in rats.

  2007cited by this paper
• Differential anxiogenic, aversive, and locomotor effects of THC in adolescent and adult rats

  2007cited by this paper
• Interactions between THC and cannabidiol in mouse models of cannabinoid activity

  2006cited by this paper
• Sex Differences and Hormonal Influences on Acquisition of Cocaine Self-Administration in Rats

  2006cited by this paper
• A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.

  2006cited by this paper
• Sex differences in the contribution of nicotine and nonpharmacological stimuli to nicotine self-administration in rats

  2005cited by this paper
• Sex differences in the escalation of intravenous cocaine intake following long- or short-access to cocaine self-administration.

  2004cited by this paper
• DREAM ablation selectively alters THC place aversion and analgesia but leaves intact the motivational and analgesic effects of morphine

  2004cited by this paper
• Sex differences in the acquisition of IV methamphetamine self-administration and subsequent maintenance under a progressive ratio schedule in rats

  2004cited by this paper
• Sex Differences in the Behavioral Effects of 24-h/day Access to Cocaine under a Discrete Trial Procedure

  2004cited by this paper
• Cannabinoid receptors and their ligands.

  2002cited by this paper
• Intravenous cocaine and heroin self-administration in rats selectively bred for differential saccharin intake: phenotype and sex differences

  2002cited by this paper
• Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors.

  2002cited by this paper
• Intravenous self-administration of the cannabinoid CB1 receptor agonist WIN 55,212-2 in rats

  2001cited by this paper
• Absence of delta -9-tetrahydrocannabinol dysphoric effects in dynorphin-deficient mice.

  2001cited by this paper
• A behavioural model to reveal place preference to delta 9-tetrahydrocannabinol in mice.

  2000cited by this paper
• Self-administration behavior is maintained by the psychoactive ingredient of marijuana in squirrel monkeys

  2000cited by this paper
• Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice.

  1998cited by this paper
• Behavioural and biochemical evidence for signs of abstinence in mice chronically treated with Δ‐9‐tetrahydrocannabinol

  1998cited by this paper
• Endogenous cannabinoids as an aversive or counter-rewarding system in the rat.

  1997cited by this paper
• THC-induced place and taste aversions in Lewis and Sprague-Dawley rats.

  1995cited by this paper
• Conditioned place preference induced by delta 9-tetrahydrocannabinol: comparison with cocaine, morphine, and food reward.

  1995cited by this paper
• Effects of dopamine D-1 and D-2 antagonists on cocaine self-administration under different schedules of reinforcement in the rat.

  1994cited by this paper
• Prediction of abuse liability of drugs using IV self-administration by rats

  1983cited by this paper
• Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects.

  1982cited by this paper
• Effects of body weight levels on cannabis self-injection.

  1980cited by this paper
• Preexposure to delta-9-THC blocks THC-induced conditioned taste aversion in rats.

  1980cited by this paper
• Self-administration of delta 9-tetrahydrocannabinol by rats.

  1979cited by this paper
• Intravenous self-administration of drugs in rats.

  1978cited by this paper
• Failure obtain “cannabis-directed behavior” and abstinence syndrome in rats chronically treated with Cannabis sativa extracts

  1974cited by this paper
• Cannabidiol interferes with the effects of delta 9 - tetrahydrocannabinol in man.

  1974cited by this paper
• Reluctance of rats to drink hashish suspensions: Free-choice and forced consumption, and the effects of hypothalamic stimulation

  1974cited by this paper
• Pharmacological interaction between cannabidiol and delta 9-tetrahydrocannabinol.

  1973cited by this paper
• Delta 9-tetrahydrocannabinol: aversive effects in rat at high doses.

  1972cited by this paper
• Experimental Morphine Addiction: Method for Automatic Intravenous Injections in Unrestrained Rats

  1962cited by this paper

• Structural and dynamic mechanisms of cannabinoid receptors.

  2025cites this paper
• Pharmacotherapy for Cannabis Use Disorder: Preclinical and Clinical Models.

  2025cites this paper
• Molecular mechanisms and pharmacology of cannabinoids: from theory to practice

  2025cites this paper
• Advancing Preclinical Models for Medications Development for Cannabis Use Disorder: Self-Administration and Beyond

  2025cites this paper
• Cannabidiol and addiction.

  2024cites this paper
• A critical assessment of the abuse, dependence and associated safety risks of naturally occurring and synthetic cannabinoids

  2024cites this paper
• β-caryophyllene inhibits heroin self-administration, but does not alter opioid-induced antinociception in rodents.

  2024cites this paper
• Cannabis use disorder: from neurobiology to treatment

  2024cites this paper
• Cannabidiol enhances socially transmitted food preference: a role of acetylcholine in the mouse basal forebrain

  2024cites this paper
• Enhancing translation: A need to leverage complex preclinical models of addictive drugs to accelerate substance use treatment options.

  2024cites this paper
• Role of Neuronal Nicotinic Acetylcholine Receptors in Cannabinoid Dependence.

  2023cites this paper
• Sex Differences in the Neuropsychiatric Effects and Pharmacokinetics of Cannabidiol: A Scoping Review

  2022influential citation
• Nicotine enhances intravenous self-administration of cannabinoids in adult rats

  2022influential citation
• Optogenetic brain‐stimulation reward: A new procedure to re‐evaluate the rewarding versus aversive effects of cannabinoids in dopamine transporter‐Cre mice

  2021cites this paper
• Cannabis use, abuse, and withdrawal: Cannabinergic mechanisms, clinical, and preclinical findings

  2021cites this paper
• Self-administration of inhaled delta-9-tetrahydrocannabinol and synthetic cannabinoids in non-human primates.

  2021cites this paper
• Environmental Enrichment and the Effects on Drug Abuse Vulnerability: The Last Ten Years

  2021cites this paper
• Dopamine, behavior, and addiction

  2021cites this paper
• Cannabinoids and the endocannabinoid system in reward processing and addiction: from mechanisms to interventions


  2020cites this paper
• Molecular Mechanism and Cannabinoid Pharmacology.

  2020cites this paper
• Intravenous self-administration of delta-9-THC in adolescent rats produces long-lasting alterations in behavior and receptor protein expression

  2020influential citation
• Adolescent cannabis use disorders

  2020cites this paper
• One Is Not Enough: Understanding and Modeling Polysubstance Use

  2020cites this paper
• Disentangling the lasting effects of adolescent cannabinoid exposure.

  2020cites this paper
• Intravenous self-administration of delta-9-THC in adolescent rats produces long-lasting alterations in behavior and receptor protein expression

  2020influential citation
• Self-administration of edible Δ9-tetrahydrocannabinol and associated behavioral effects in mice.

  2019influential citation
• The Cerebellum, THC, and Cannabis Addiction: Findings from Animal and Human Studies

  2019cites this paper
• Vaporized Cannabis Extracts Have Reinforcing Properties and Support Conditioned Drug-Seeking Behavior in Rats

  2019cites this paper
• Assessment of Acute Motor Effects and Tolerance Following Self-Administration of Alcohol and Edible THC in Adolescent Male Mice.

  2019cites this paper
• Assessment of Acute Motor Effects and Tolerance Following Self-Administration of Alcohol and Edible THC in Adolescent Male Mice.

  2019cites this paper
• Cannabis effects on brain structure, function, and cognition: considerations for medical uses of cannabis and its derivatives

  2019cites this paper
• Effects in rats of adolescent exposure to cannabis smoke or THC on emotional behavior and cognitive function in adulthood

  2019cites this paper
• Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats

  2019cites this paper
• Old and new synthetic cannabinoids: lessons from animal models

  2018cites this paper
• Social Factors and Animal Models of Cannabis Use.

  2018cites this paper
• A Model of Δ9-Tetrahydrocannabinol Self-administration and Reinstatement That Alters Synaptic Plasticity in Nucleus Accumbens.

  2018cites this paper
• Evaluation of reinforcing and aversive effects of voluntary &Dgr;9‐tetrahydrocannabinol ingestion in rats

  2018cites this paper
• Antagonism of the kappa opioid receptor attenuates THC‐induced place aversions in adult male Sprague‐Dawley rats

  2017cites this paper
• Sex as a biological variable: Drug use and abuse.

  2017cites this paper