Use of nonsteroidal anti-inflammatory drugs and risk of oral cancer: a cohort study

Søren Friis,A. Poulsen,L. Pedersen,John A. Baron,H. T. Sørensen

Published 2006 in British Journal of Cancer

ABSTRACT

Epidemiologic data regarding the chemopreventive potential of nonsteroidal anti-inflammatory drugs (NSAIDs) against oral cancer are sparse. We found a relative risk for oral cancer of 1.2 (95% CI, 1.0–1.6) among 169 589 Danish NSAID users (⩾2 prescriptions), with no apparent trends in subgroups. Our study provided no clear evidence that NSAIDs may protect against oral cancer.

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