The problem of packing ellipsoids of different sizes and shapes into an ellipsoidal container so as to minimize a measure of overlap between ellipsoids is considered. A bilevel optimization formulation is given, together with an algorithm for the general case and a simpler algorithm for the special case in which all ellipsoids are in fact spheres. Convergence results are proved and computational experience is described and illustrated. The motivating application---chromosome organization in the human cell nucleus---is discussed briefly, and some illustrative results are presented.
ABSTRACT
PUBLICATION RECORD
- Publication year
2012
- Venue
SIAM Review
- Publication date
2012-04-01
- Fields of study
Mathematics, Computer Science
- Identifiers
- External record
- Source metadata
Semantic Scholar
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