Differential chemical probing of a group II self-splicing intron identifies bases involved in tertiary interactions and supports an alternative secondary structure model of domain V.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  RNA: A publication of the RNA Society

• Publication date

  1998-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1017/S1355838298980670PMID 9740125PMCID PMC1369682
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• RNA-RNA Interactions in Nuclear Pre-mRNA Splicing

  1998cited by this paper
• Inferring RNA Structure by Phylogenetic and Genetic Analyses

  1998cited by this paper
• Ribozyme catalysis from the major groove of group II intron domain 5.

  1998cited by this paper
• Domain 5 binds near a highly conserved dinucleotide in the joiner linking domains 2 and 3 of a group II intron.

  1998cited by this paper
• Complementary sets of noncanonical base pairs mediate RNA helix packing in the group I intron active site

  1998cited by this paper
• Rules for RNA recognition of GNRA tetraloops deduced by in vitro selection: comparison with in vivo evolution

  1997cited by this paper
• Multiple tertiary interactions involving domain II of group II self-splicing introns.

  1997cited by this paper
• A group II self-splicing intron from the brown alga Pylaiella littoralis is active at unusually low magnesium concentrations and forms populations of molecules with a uniform conformation.

  1997cited by this paper
• Identification of structural elements critical for inter–domain interactions in a group II self‐splicing intron

  1997cited by this paper
• Stopped-flow fluorescence spectroscopy of a group II intron ribozyme reveals that domain 1 is an independent folding unit with a requirement for specific Mg2+ ions in the tertiary structure.

  1997cited by this paper
• Solution structure of a GAAA tetraloop receptor RNA

  1997cited by this paper
• Strategies for RNA folding.

  1996cited by this paper
• Two competing pathways for self-splicing by group II introns: a quantitative analysis of in vitro reaction rates and products.

  1996cited by this paper
• Catalytic Role of 2′-Hydroxyl Groups Within a Group II Intron Active Site

  1996cited by this paper
• Mutations of the two-nucleotide bulge of D5 of a group II intron block splicing in vitro and in vivo: phenotypes and suppressor mutations.

  1996cited by this paper
• Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing

  1996cited by this paper
• An RNA conformational change between the two chemical steps of group II self‐splicing.

  1996cited by this paper
• RNA Tertiary Structure Mediation by Adenosine Platforms

  1996cited by this paper
• RNA tectonics: towards RNA design.

  1996cited by this paper
• Catalytically critical nucleotide in domain 5 of a group II intron.

  1995cited by this paper
• U6 snRNA function in nuclear pre-mRNA splicing: a phosphorothioate interference analysis of the U6 phosphate backbone.

  1995cited by this paper
• The mitochondrial LSU rDNA of the brown alga Pylaiella littoralis reveals alpha-proteobacterial features and is split by four group IIB introns with an atypical phylogeny.

  1995cited by this paper
• Studies of point mutants define three essential paired nucleotides in the domain 5 substructure of a group II intron

  1995cited by this paper
• Frequent use of the same tertiary motif by self‐folding RNAs.

  1995cited by this paper
• Structure and activities of group II introns.

  1995cited by this paper
• A UV-induced, Mg(2+)-dependent crosslink traps an active form of domain 3 of a self-splicing group II intron.

  1995cited by this paper
• Involvement of a GNRA tetraloop in long-range RNA tertiary interactions.

  1994cited by this paper
• Catalytic site components common to both splicing steps of a group II intron.

  1994influential reference
• GAAA tetraloop and conserved bulge stabilize tertiary structure of a group I intron domain.

  1994cited by this paper
• Kinetic analysis of the 5' splice junction hydrolysis of a group II intron promoted by domain 5.

  1993cited by this paper
• Thermal unfolding of a group I ribozyme: the low-temperature transition is primarily disruption of tertiary structure.

  1993cited by this paper
• The phylogenetically predicted base-pairing interaction between alpha and alpha' is required for group II splicing in vitro.

  1993cited by this paper
• Monitoring of the cooperative unfolding of the sunY group I intron of bacteriophage T4. The active form of the sunY ribozyme is stabilized by multiple interactions with 3' terminal intron components.

  1993cited by this paper
• mRNA splicing and autocatalytic introns: distant cousins or the products of chemical determinism?

  1993cited by this paper
• Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro.

  1992cited by this paper
• A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome.

  1992cited by this paper
• "Five easy pieces".

  1991cited by this paper
• Base-pairing interactions involving the 5' and 3'-terminal nucleotides of group II self-splicing introns.

  1990cited by this paper
• Structural analysis of a group II intron by chemical modifications and minimal energy calculations.

  1990cited by this paper
• Reverse self-splicing of group II intron RNAs in vitro

  1990cited by this paper
• Comparative and functional anatomy of group II catalytic introns--a review.

  1989cited by this paper
• CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes.

  1988cited by this paper
• Multiple exon-binding sites in class II self-splicing introns.

  1987cited by this paper
• Long-range intron-exon and intron-intron pairings involved in self-splicing of class II catalytic introns.

  1987cited by this paper
• The generality of self-splicing RNA: relationship to nuclear mRNA splicing.

  1986cited by this paper
• The generality of self-splicing RNA: Relationship to nuclear mRNA splicing

  1986cited by this paper
• Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase.

  1985cited by this paper
• Comparison of fungal mitochondrial introns reveals extensive homologies in RNA secondary structure.

  1982cited by this paper

• Discovery of highly reactive self-splicing group II introns within the mitochondrial genomes of human pathogenic fungi

  2021cites this paper
• A new RNA–DNA interaction required for integration of group II intron retrotransposons into DNA targets

  2021cites this paper
• The molecular structure of long non-coding RNAs: emerging patterns and functional implications

  2020cites this paper
• Activating the branch-forming splicing pathway by reengineering the ribozyme component of a natural group II intron

  2016cites this paper
• Inactivation of group II intron RmInt1 in the Sinorhizobium meliloti genome

  2015cites this paper
• Probing RNA folding by hydroxyl radical footprinting.

  2014cites this paper
• The Molecular Interfaces of Telomerase and Telomere Proteins in Yeast and Humans

  2014cites this paper
• The Role of Mg(II) in DNA Cleavage Site Recognition in Group II Intron Ribozymes

  2014cites this paper
• Predicted group II intron lineages E and F comprise catalytically active ribozymes

  2013cites this paper
• The Brown Algae Pl.LSU/2 Group II Intron-Encoded Protein Has Functional Reverse Transcriptase and Maturase Activities

  2013cites this paper
• RNA recognition by the DNA end-binding Ku heterodimer.

  2013cites this paper
• Alternative splicing of an ORF-less group II intron in Clostridium tetani

  2013cites this paper
• Structural architecture of the human long non-coding RNA, steroid receptor RNA activator

  2012cites this paper
• An evolutionary and biochemical characterization of a self-splicing group II intron and its encoded LAGLIDADG homing endonuclease in Leptographium truncatum

  2010cites this paper
• A structural analysis of the group II intron active site and implications for the spliceosome.

  2010cites this paper
• ionic conditions endonuclease and self-splices under moderate temperature and A group II intron encodes a functional LAGLIDADG homing

  2010cites this paper
• A group II intron encodes a functional LAGLIDADG homing endonuclease and self-splices under moderate temperature and ionic conditions.

  2010cites this paper
• The ribozyme core of group II introns: a structure in want of partners.

  2009cites this paper
• for the spliceosome A structural analysis of the group II intron active site and implications

  2009cites this paper
• Probing protein surface accessibility with solvent and paramagnetic molecules

  2009cites this paper
• Tertiary architecture of the Oceanobacillus iheyensis group II intron.

  2009influential citation
• Specificity of Mg2+ binding at the Group II intron branch site.

  2008cites this paper
• The Pentatricopeptide Repeat Gene OTP43 Is Required for trans-Splicing of the Mitochondrial nad1 Intron 1 in Arabidopsis thaliana[W]

  2007cites this paper
• Group II introns: structure, folding and splicing mechanism

  2007cites this paper
• DMS footprinting of structured RNAs and RNA–protein complexes

  2007cites this paper
• Consecutive GA pairs stabilize medium-size RNA internal loops.

  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2005cites this paper
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  2004cites this paper
• Using an RNA secondary structure partition function to determine confidence in base pairs predicted by free energy minimization.

  2004cites this paper
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  2004cites this paper
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  2004cites this paper
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  2004cites this paper
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  2003cites this paper
• Group II Introns: Structure and Catalytic Versatility of Large Natural Ribozymes

  2003influential citation
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  2002cites this paper
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  2002cites this paper
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  2002cites this paper
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  2002cites this paper
• Variation in sequence and RNA editing within core domains of mitochondrial group II introns among plants

  2001cites this paper
• The intramolecular stem-loop structure of U6 snRNA can functionally replace the U6atac snRNA stem-loop.

  2001cites this paper
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  2001cites this paper
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  2000cites this paper
• Organisation et structure des génomes mitochondriaux des algues brunes Pylaiella littoralis et Laminaria digitata

  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  1999cites this paper
• Analysis of the cooperative thermal unfolding of the td intron of bacteriophage T4.

  1999cites this paper
• Antagonistic substrate binding by a group II intron ribozyme.

  1999cites this paper
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  1999cites this paper
• Tight binding of the 5′ exon to domain I of a group II self‐splicing intron requires completion of the intron active site

  1999influential citation
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  1999cites this paper