How does the plasma membrane participate in cellular signaling by receptors for immunoglobulin E?

Accumulating evidence strongly supports the view that the plasma membrane participates in transmembrane signaling by IgE-receptors (IgE-Fc epsilon RI) through the formation of lipid-based domains, also known as rafts. Ongoing biochemical and biophysical experiments investigate the composition, structure, and dynamics of the corresponding membrane components and how these are related to functional coupling between Fc epsilon RI and Lyn tyrosine kinase to initiate signaling in mast cells.

• Publication year

  1999

• Venue

  Biophysical Chemistry

• Publication date

  1999-12-13

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0301-4622(99)00110-6PMID 10631794
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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