Quantification of Compactness and Local Order in the Ensemble of the Intrinsically Disordered Protein FCP1.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Physical Chemistry B

• Publication date

  2016-08-23

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/acs.jpcb.6b06934PMID 27551949
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies*

  2016cited by this paper
• Assessing Coupled Protein Folding and Binding Through Temperature-Dependent Isothermal Titration Calorimetry.

  2016cited by this paper
• Influence of Glu/Arg, Asp/Arg, and Glu/Lys Salt Bridges on α-Helical Stability and Folding Kinetics.

  2016cited by this paper
• Structural Ensembles of Intrinsically Disordered Proteins Depend Strongly on Force Field: A Comparison to Experiment.

  2015cited by this paper
• Quantitative biophysical characterization of intrinsically disordered proteins.

  2015cited by this paper
• Investigating protein conformational energy landscapes and atomic resolution dynamics from NMR dipolar couplings: a review

  2015cited by this paper
• Conformation and Dynamics of the Troponin I C-Terminal Domain: Combining Single-Molecule and Computational Approaches for a Disordered Protein Region.

  2015cited by this paper
• A primer for carbon‐detected NMR applications to intrinsically disordered proteins in solution

  2015cited by this paper
• Relating sequence encoded information to form and function of intrinsically disordered proteins.

  2015cited by this paper
• Classification of Intrinsically Disordered Regions and Proteins

  2014cited by this paper
• Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy.

  2014cited by this paper
• Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association

  2014cited by this paper
• Predictive atomic resolution descriptions of intrinsically disordered hTau40 and α-synuclein in solution from NMR and small angle scattering.

  2014cited by this paper
• Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation.

  2014cited by this paper
• The dynamic duo: Combining NMR and small angle scattering in structural biology

  2014cited by this paper
• Investigation of Intramolecular Dynamics and Conformations of α-, β- and γ-Synuclein

  2014cited by this paper
• Role of Ordered Proteins in the Folding-Upon-Binding of Intrinsically Disordered Proteins.

  2014cited by this paper
• Thermodynamic and structural determinants of differential Pdx1 binding to elements from the insulin and IAPP promoters.

  2013cited by this paper
• Mapping protein conformational energy landscapes using NMR and molecular simulation.

  2013cited by this paper
• Describing intrinsically disordered proteins at atomic resolution by NMR.

  2013cited by this paper
• Characterization of disordered proteins with ENSEMBLE

  2013cited by this paper
• Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues

  2013cited by this paper
• Native-based simulations of the binding interaction between RAP74 and the disordered FCP1 peptide.

  2013cited by this paper
• Differences in β-strand populations of monomeric Aβ40 and Aβ42.

  2013cited by this paper
• How Random are Intrinsically Disordered Proteins? A Small Angle Scattering Perspective

  2012cited by this paper
• Determination of secondary structure populations in disordered states of proteins using nuclear magnetic resonance chemical shifts.

  2012cited by this paper
• Carbon-Detected (15)N NMR Spin Relaxation of an Intrinsically Disordered Protein: FCP1 Dynamics Unbound and in Complex with RAP74.

  2012cited by this paper
• Intrinsic disorder in cell signaling and gene transcription.

  2012cited by this paper
• Structural characterization of intrinsically disordered proteins by the combined use of NMR and SAXS.

  2012cited by this paper
• Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering.

  2012cited by this paper
• Atomistic simulations reveal structural disorder in the RAP74-FCP1 complex.

  2011cited by this paper
• The disordered C-terminus of the RNA polymerase II phosphatase FCP1 is partially helical in the unbound state.

  2011cited by this paper
• Defining conformational ensembles of intrinsically disordered and partially folded proteins directly from chemical shifts.

  2010cited by this paper
• Certification of Molecular Dynamics Trajectories with NMR Chemical Shifts

  2010cited by this paper
• Induced fit, conformational selection and independent dynamic segments: an extended view of binding events.

  2010cited by this paper
• A self-consistent description of the conformational behavior of chemically denatured proteins from NMR and small angle scattering.

  2009cited by this paper
• NMR assignment of the intrinsically disordered C-terminal region of Homo sapiens FCP1 in the unbound state

  2009cited by this paper
• Methods for Monte Carlo simulations of biomacromolecules.

  2009cited by this paper
• ABSINTH: A new continuum solvation model for simulations of polypeptides in aqueous solutions

  2009cited by this paper
• Interplay of α-synuclein binding and conformational switching probed by single-molecule fluorescence

  2009cited by this paper
• Anton, a special-purpose machine for molecular dynamics simulation

  2008cited by this paper
• A multifaceted approach to the interpretation of NMR order parameters: a case study of a dynamic alpha-helix.

  2008cited by this paper
• Malleable machines take shape in eukaryotic transcriptional regulation.

  2008cited by this paper
• Quantitative characterization of intrinsic disorder in polyglutamine: insights from analysis based on polymer theories.

  2007cited by this paper
• The MUMO (minimal under-restraining minimal over-restraining) method for the determination of native state ensembles of proteins

  2007cited by this paper
• Atomic-level characterization of disordered protein ensembles.

  2007cited by this paper
• A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures

  2007cited by this paper
• Comparison of multiple Amber force fields and development of improved protein backbone parameters

  2006cited by this paper
• Sensitivity of secondary structure propensities to sequence differences between alpha- and gamma-synuclein: implications for fibrillation.

  2006cited by this paper
• Analysis of molecular recognition features (MoRFs).

  2006cited by this paper
• Conformation of the backbone in unfolded proteins.

  2006cited by this paper
• Sensitivity of secondary structure propensities to sequence differences between α‐ and γ‐synuclein: Implications for fibrillation

  2006cited by this paper
• A structural perspective of CTD function.

  2005cited by this paper
• Mapping long-range interactions in alpha-synuclein using spin-label NMR and ensemble molecular dynamics simulations.

  2005cited by this paper
• UCSF Chimera—A visualization system for exploratory research and analysis

  2004cited by this paper
• Unfolded proteins and protein folding studied by NMR.

  2004cited by this paper
• Random-coil behavior and the dimensions of chemically unfolded proteins.

  2004cited by this paper
• Determination of an ensemble of structures representing the denatured state of the bovine acyl-coenzyme a binding protein.

  2004cited by this paper
• NMR structure of a complex containing the TFIIF subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1

  2003cited by this paper
• Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF

  2003cited by this paper
• General framework for studying the dynamics of folded and nonfolded proteins by NMR relaxation spectroscopy and MD simulation.

  2002cited by this paper
• Automated prediction of 15N, 13Cα, 13Cβ and 13C′ chemical shifts in proteins using a density functional database

  2001cited by this paper
• A fast method to sample real protein conformational space

  2000cited by this paper
• FCP1, the RAP74-Interacting Subunit of a Human Protein Phosphatase That Dephosphorylates the Carboxyl-terminal Domain of RNA Polymerase IIO*

  1998cited by this paper
• VMD: visual molecular dynamics.

  1996cited by this paper
• Do salt bridges stabilize proteins? A continuum electrostatic analysis

  1994cited by this paper
• Vibrational approach to the dynamics of an α‐helix

  1979cited by this paper
• Fluctuations of an alpha-helix.

  1976cited by this paper
• Fluctuations of an α‐helix

  1976cited by this paper

• Capturing secondary structure in coarse grained intrinsically disordered proteins with simulations driven by chemical shifts

  2026cites this paper
• Accurate conformational ensembles of intrinsically disordered proteins using reweighting based on NMR chemical shifts.

  2026cites this paper
• A stickiness scale for disordered proteins

  2026cites this paper
• Phosphorylation of disordered proteins tunes local and global intramolecular interactions

  2024cites this paper
• Phosphorylation of disordered proteins tunes local and global intramolecular interactions

  2024cites this paper
• Direct prediction of intrinsically disordered protein conformational properties from sequence

  2023cites this paper
• 13C Direct Detected NMR for Challenging Systems

  2022cites this paper
• Investigating the ferric ion binding site of magnetite biomineralisation protein Mms6

  2020cites this paper
• Connecting Coil-to-Globule Transitions to Full Phase Diagrams for Intrinsically Disordered Proteins

  2020cites this paper
• Influence of electrostatic forces on the association kinetics and conformational ensemble of an intrinsically disordered protein

  2020cites this paper
• Improvements to the ABSINTH Force Field for Proteins Based on Experimentally Derived Amino Acid Specific Backbone Conformational Statistics.

  2019cites this paper
• Information theoretic measures for quantifying sequence–ensemble relationships of intrinsically disordered proteins

  2019cites this paper
• Solution Ensemble of the C-Terminal Domain from the Transcription Factor Pdx1 Resembles an Excluded Volume Polymer.

  2018cites this paper
• Evolved sequence features within the intrinsically disordered tail influence FtsZ assembly and bacterial cell division

  2018cites this paper
• Revealing the distinct folding phases of an RNA three-helix junction

  2018cites this paper
• Computational and theoretical advances in studies of intrinsically disordered proteins.

  2017cites this paper
• Application of NMR to studies of intrinsically disordered proteins.

  2017cites this paper
• Sequence Determinants of the Individual and Collective Behaviour of Intrinsically Disordered Proteins

  2017cites this paper
• Control of transcriptional activity by design of charge patterning in the intrinsically disordered RAM region of the Notch receptor

  2017cites this paper
• Visualizing single-stranded nucleic acids in solution

  2016cites this paper