Binding of a small molecule water channel inhibitor to aquaporin Z examined by solid-state MAS NMR

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Journal of Biomolecular NMR

• Publication date

  2018-06-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/s10858-018-0195-0PMID 29916035
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A generic high-throughput assay to detect aquaporin functional mutants: Potential application to discovery of aquaporin inhibitors.

  2015cited by this paper
• Aquaporins: important but elusive drug targets

  2014cited by this paper
• Modeling the membrane environment has implications for membrane protein structure and function: Influenza A M2 protein

  2013cited by this paper
• Solid state NMR and protein-protein interactions in membranes.

  2013cited by this paper
• Preparation of supported lipid membranes for aquaporin Z incorporation.

  2012cited by this paper
• Aquaporins in clinical medicine.

  2012cited by this paper
• Inhibition of aquaporin-1 dependent angiogenesis impairs tumour growth in a mouse model of melanoma

  2012cited by this paper
• Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

  2011cited by this paper
• Expression of aquaporin 5 increases proliferation and metastasis potential of lung cancer

  2010cited by this paper
• Structural origins of pH‐dependent chemical shifts in the B1 domain of protein G

  2010cited by this paper
• Rapid and reversible inhibition of aquaporin-4 by zinc.

  2009cited by this paper
• Aquaporins—new players in cancer biology

  2008cited by this paper
• Combined chemical shift changes and amino acid specific chemical shift mapping of protein–protein interactions

  2007cited by this paper
• Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel*

  2006cited by this paper
• Physiological roles of glycerol-transporting aquaporins: the aquaglyceroporins

  2006cited by this paper
• Quaternary Ammonium Compounds as Water Channel Blockers

  2006cited by this paper
• What makes an aquaporin a glycerol channel? A comparative study of AqpZ and GlpF.

  2005cited by this paper
• Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption

  2005cited by this paper
• INTO WATER TRANSPORT AND EDEMA IN THE ENTRAL NERVOUS SYSTEM FROM PHENOTYPE ANALYSIS OF QUAPORIN-4 NULL MICE

  2004cited by this paper
• New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice.

  2004cited by this paper
• Architecture and Selectivity in Aquaporins: 2.5 Å X-Ray Structure of Aquaporin Z

  2003cited by this paper
• Aquaporin Deletion in Mice Reduces Intraocular Pressure and Aqueous Fluid Production

  2002cited by this paper
• Mapping protein-protein interactions in solution by NMR spectroscopy.

  2002cited by this paper
• A method for efficient isotopic labeling of recombinant proteins

  2001cited by this paper
• Physiological importance of aquaporins: lessons from knockout mice

  2000cited by this paper
• The importance of aquaporin water channel protein structures

  2000cited by this paper
• Visualization of AqpZ-Mediated Water Permeability in Escherichia coli by Cryoelectron Microscopy

  1999cited by this paper
• Aquaporin water channels in mammals

  1997cited by this paper
• [Aquaporin water channels].

  1996cited by this paper
• The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel.

  1993cited by this paper
• The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy.

  1992cited by this paper
• Rhodopsin-phospholipid reconstitution by dialysis removal of octyl glucoside.

  1982cited by this paper
• Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes.

  1979cited by this paper

• Analysis of solid-state NMR data facilitated by MagRO_NMRViewJ with Graph_Robot: Application for membrane protein and amyloid.

  2024cites this paper
• Application of polymersomes in membrane protein study and drug discovery: Progress, strategies, and perspectives

  2022cites this paper
• Dynamic Interactions between Brilliant Green and MscL Investigated by Solid-State NMR Spectroscopy and Molecular Dynamics Simulations.

  2022cites this paper