Role of Dynamic Loading on Early Stage of Bone Fracture Healing

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Annals of Biomedical Engineering

• Publication date

  2018-07-09

• Fields of study

  Medicine, Chemistry, Engineering

• Identifiers
  DOI 10.1007/s10439-018-2083-xPMID 29987542
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The relationship between interfragmentary movement and cell differentiation in early fracture healing under locking plate fixation

  2016cited by this paper
• Influence of fracture geometry on bone healing under locking plate fixations: A comparison between oblique and transverse tibial fractures.

  2016cited by this paper
• The relationship between interfragmentary movement and cell differentiation in early fracture healing under locking plate fixation

  2015cited by this paper
• Time Evolution of Deformation in a Human Cartilage Under Cyclic Loading

  2014cited by this paper
• Cyclic Mechanical Loading Enables Solute Transport and Oxygen Supply in Bone Healing: An In Vitro Investigation

  2014cited by this paper
• Bone repair: new developments in growth factor delivery systems and their mathematical modeling.

  2012cited by this paper
• Role of chemical and mechanical stimuli in mediating bone fracture healing

  2012cited by this paper
• Nanomechanics of the Cartilage Extracellular Matrix.

  2011cited by this paper
• Interstitial flow influences direction of tumor cell migration through competing mechanisms

  2011cited by this paper
• A hybrid bioregulatory model of angiogenesis during bone fracture healing

  2011cited by this paper
• Chemokines in mesenchymal stem cell therapy for bone repair: a novel concept of recruiting mesenchymal stem cells and the possible cell sources

  2011cited by this paper
• SOLUTE TRANSPORT IN CYCLIC DEFORMED HETEROGENEOUS ARTICULAR CARTILAGE

  2011cited by this paper
• Influence of the fixation stability on the healing time--a numerical study of a patient-specific fracture healing process.

  2010cited by this paper
• Temporal tissue patterns in bone healing of sheep

  2010cited by this paper
• Connecting biology and mechanics in fracture healing: an integrated mathematical modeling framework for the study of nonunions

  2010cited by this paper
• Influence of the frequency of the external mechanical stimulus on bone healing: a computational study.

  2010cited by this paper
• Effects of construct stiffness on healing of fractures stabilized with locking plates.

  2010cited by this paper
• Controlled Dynamization to Enhance Reconstruction Capacity of Tissue-Engineered Bone in Healing Critically Sized Bone Defects: An In Vivo Study in Goats

  2009cited by this paper
• Integrated model of IGF-I mediated biosynthesis in a deformed articular cartilage

  2009cited by this paper
• The role of endogenous bone morphogenetic proteins in normal skeletal repair.

  2009cited by this paper
• Cells, growth factors and bioactive surface properties in a mechanobiological model of implant healing.

  2009cited by this paper
• Simulation of fracture healing incorporating mechanoregulation of tissue differentiation and dispersal/proliferation of cells

  2008cited by this paper
• A mechano-regulatory bone-healing model incorporating cell-phenotype specific activity.

  2008cited by this paper
• Influence of perfusion and cyclic compression on proliferation and differentiation of bone marrow stromal cells in 3-dimensional culture.

  2008cited by this paper
• Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging.

  2008cited by this paper
• A fully coupled poroelastic reactive-transport model of cartilage.

  2008cited by this paper
• Angiogenesis in bone fracture healing: a bioregulatory model.

  2008cited by this paper
• A Mechanobiological Model for Tissue Differentiation that Includes Angiogenesis: A Lattice-Based Modeling Approach

  2008cited by this paper
• Regulatory Effects of Mechanical Strain on the Chondrogenic Differentiation of MSCs in a Collagen-GAG Scaffold: Experimental and Computational Analysis

  2008cited by this paper
• The effect of cyclic deformation and solute binding on solute transport in cartilage.

  2007cited by this paper
• Computational simulation of fracture healing: influence of interfragmentary movement on the callus growth.

  2007cited by this paper
• Solute transport in cartilage undergoing cyclic deformation

  2007cited by this paper
• Biomechanical model to simulate tissue differentiation and bone regeneration: Application to fracture healing

  2006cited by this paper
• Mathematical modeling of fracture healing in mice: comparison between experimental data and numerical simulation results

  2006cited by this paper
• Comparison of biophysical stimuli for mechano-regulation of tissue differentiation during fracture healing.

  2006cited by this paper
• In vivo cyclic axial compression affects bone healing in the mouse tibia

  2006cited by this paper
• Shear Does Not Necessarily Inhibit Bone Healing

  2006cited by this paper
• Synergy between interstitial flow and VEGF directs capillary morphogenesis in vitro through a gradient amplification mechanism.

  2005cited by this paper
• Comparative performance of a flexible fixation implant to a rigid implant in static and repetitive incremental loading

  2005cited by this paper
• Eine neue Theorie über den Einfluß mechanischer Reize auf die Differenzierung der Stützgewebe

  2004cited by this paper
• Fibroblast alignment under interstitial fluid flow using a novel 3-D tissue culture model.

  2003cited by this paper
• Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs).

  2003cited by this paper
• Modeling of neutral solute transport in a dynamically loaded porous permeable gel: implications for articular cartilage biosynthesis and tissue engineering.

  2003cited by this paper
• The initial phase of fracture healing is specifically sensitive to mechanical conditions

  2003cited by this paper
• Beneficial effects of moderate, early loading and adverse effects of delayed or excessive loading on bone healing.

  2003cited by this paper
• Controlled Induction of a Pseudarthrosis: A Study Using a Rodent Model

  2003cited by this paper
• A mechano-regulation model for tissue differentiation during fracture healing: analysis of gap size and loading.

  2002cited by this paper
• Evolution of the internal fixation of long bone fractures. The scientific basis of biological internal fixation: choosing a new balance between stability and biology.

  2002cited by this paper
• Differential Temporal Expression of Members of the Transforming Growth Factor β Superfamily During Murine Fracture Healing

  2002cited by this paper
• Monitoring and healing analysis of 100 tibial shaft fractures

  2002cited by this paper
• A mathematical framework to study the effects of growth factor influences on fracture healing.

  2001cited by this paper
• The effect of dynamic compression on the response of articular cartilage to insulin‐like growth factor‐I

  2001cited by this paper
• The relationship of the compressive modulus of articular cartilage with its deformation response to cyclic loading: does cartilage optimize its modulus so as to minimize the strains arising in it due to the prevalent loading regime?

  2001cited by this paper
• Mechanical Stimulation by External Application of Cyclic Tensile Strains Does Not Effectively Enhance Bone Healing

  2001cited by this paper
• An In Vivo Model for Investigations of Mechanical Signal Transduction in Trabecular Bone

  2000cited by this paper
• The influence of mechanical stimulus on the pattern of tissue differentiation in a long bone fracture--an FEM study.

  2000cited by this paper
• Growth Factor Regulation of Fracture Repair

  1999cited by this paper
• Magnitudes of local stress and strain along bony surfaces predict the course and type of fracture healing.

  1998cited by this paper
• Enhancement of fracture healing by mechanical and surgical intervention.

  1998cited by this paper
• Growth factors in bone

  1998cited by this paper
• The effects of external mechanical stimulation on the healing of diaphyseal osteotomies fixed by flexible external fixation.

  1998cited by this paper
• Effects of Mechanical Factors on the Fracture Healing Process

  1998cited by this paper
• Biophysical stimuli on cells during tissue differentiation at implant interfaces

  1997cited by this paper
• A biomechanical regulatory model for periprosthetic fibrous-tissue differentiation

  1997cited by this paper
• ESB Research Award 1996. Biophysical stimuli on cells during tissue differentiation at implant interfaces.

  1997cited by this paper
• Early Fracture Callus in the Diaphysis of Human Long Bones: Histologic and Ultrastructural Study

  1995cited by this paper
• A mechanochemical model for adult dermal wound contraction and the permanence of the contracted tissue displacement profile.

  1995cited by this paper
• Regulation of differentiation pathway of skeletal mesenchymal cells in cell lines by transforming growth factor-beta superfamily.

  1995cited by this paper
• A Mechanochemical Model for Adult Dermal Wound Contraction and the Permanence of the Contracted Tissue Displacement Profile

  1995cited by this paper
• Axial movement and tibial fractures. A controlled randomised trial of treatment.

  1991cited by this paper
• Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur

  1990cited by this paper
• Role of Transforming Growth Factor‐β in Fracture Repair

  1990cited by this paper
• Role of transforming growth factor-beta in fracture repair.

  1990cited by this paper
• The cartilaginous fracture callus in rats.

  1987cited by this paper
• The influence of induced micromovement upon the healing of experimental tibial fractures.

  1985cited by this paper
• Comparison of cyclic loading versus constant compression in the treatment of long-bone fractures in rabbits.

  1981cited by this paper
• Physical and biological aspects of fracture healing with special reference to internal fixation.

  1979cited by this paper
• The biology of fracture healing in long bones.

  1978cited by this paper
• [A new theory on the influence of mechanical stimuli on the differentiation of supporting tissue. The tenth contribution to the functional anatomy and causal morphology of the supporting structure].

  1960cited by this paper
• Eine neue Theorie ber den Einflu mechanischer Reize auf die Differenzierung der Sttzgewebe: Zehnter Beitrag zur funktionellen Anatomie und kausalen Morphologie des Sttzapparates

  1960cited by this paper

• Establishment of a mechano-biological computational framework for fracture healing and investigation of initial condition effects.

  2026cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2024cites this paper
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  2024cites this paper
• Engineering natural DNA matrices with halloysite nanotubes to fabricate injectable therapeutic hydrogels for bone regeneration

  2024cites this paper
• Impacts of post‐operation loading and fixation implant on the healing process of fractured tibia

  2024cites this paper
• Material synthesis and design optimization of biomaterials for biomedical implant applications

  2024cites this paper
• Forces required to dynamize sliding screws in gamma nail and selfdynamizable internal fixator

  2024cites this paper
• Computational models of bone fracture healing and applications: a review

  2024cites this paper
• Effect of uncertain clinical conditions on the early healing and stability of distal radius fractures

  2023cites this paper
• Fracture healing research: Recent insights

  2023cites this paper
• Computational Modelling for Managing Pathways to Cartilage Failure.

  2023cites this paper
• The impact of osteoporosis and diabetes on fracture healing under different loading conditions

  2023cites this paper
• Loss of Bcl-3 delays bone fracture healing through activating NF-κB signaling in mesenchymal stem cells

  2022cites this paper
• Progress of Periosteal Osteogenesis: The Prospect of In Vivo Bioreactor

  2022cites this paper
• Aseptic non-union fracture of ulna but union fracture of radius following internal fixation procedure: A case report

  2022cites this paper
• Biomechanical evaluation on a novel design of biodegradable embossed locking compression plate for orthopaedic applications using finite element analysis

  2022cites this paper
• Influences of variability and uncertainty in vertical and horizontal surface roughness on articular cartilage lubrication

  2022cites this paper
• Mechanical properties and mechanism of soil treated with nano-aqueous adhesive (NAA)

  2022cites this paper
• Influence of therapeutic grip exercises induced loading rates in distal radius fracture healing with volar locking plate fixation

  2022cites this paper
• Influence of muscle loading on early-stage bone fracture healing.

  2022cites this paper
• Bone tissue engineering scaffolds with HUVECs/hBMSCs cocultured on 3D-printed composite bioactive ceramic scaffolds promoted osteogenesis/angiogenesis

  2022cites this paper
• On computational predictions of fluid flow and its effects on bone healing in dental implant treatments: an investigation of spatiotemporal fluid flow in cyclic loading

  2022cites this paper
• Reliability assessment of concrete under external sulfate attack

  2021cites this paper
• A probabilistic approach for modelling bone fracture healing under Ilizarov circular fixator

  2021cites this paper
• Design approaches and challenges for biodegradable bone implants: a review

  2021cites this paper
• Optimal time-dependent levels of weight-bearing for bone fracture healing under Ilizarov circular fixators.

  2021cites this paper
• Balance Between Mechanical Stability and Mechano-Biology of Fracture Healing Under Volar Locking Plate

  2021cites this paper
• Quercetin promotes locomotor function recovery and axonal regeneration through induction of autophagy after spinal cord injury

  2021cites this paper
• Clinical outcomes of frozen autograft reconstruction for the treatment of primary bone sarcoma in adolescents and young adults

  2021cites this paper
• Diagnostic prediction of ovine fracture healing outcomes via a novel multi-location direct electromagnetic coupling antenna

  2021influential citation
• The American College of Foot and Ankle Surgeons® Clinical Consensus Statement: Hallux Valgus.

  2021cites this paper
• Role of TNF-α in early-stage fracture healing under normal and diabetic conditions

  2021cites this paper
• Variable Fixation Technology Provides Rigid as Well as Progressive Dynamic Fixation: A Biomechanical Investigation.

  2020cites this paper
• The Application of Digital Volume Correlation (DVC) to Evaluate Strain Predictions Generated by Finite Element Models of the Osteoarthritic Humeral Head

  2020cites this paper
• Refining anticipation of degraded bone microstructures during osteoporosis based on statistical homogenized reconstruction method via quality of connection function

  2020cites this paper
• The Bone Buttress Theory: The Effect of the Mechanical Loading of Bone on the Osseointegration of Dental Implants

  2020cites this paper
• The investigation of bone fracture healing under intramembranous and endochondral ossification

  2020cites this paper
• The effect of the degradation pattern of biodegradable bone plates on the healing process using a biphasic mechano-regulation theory

  2020cites this paper
• Crestal bone changes around early vs. conventionally loaded implants with a multiphosphonate coated surface: a randomized pilot clinical trial.

  2020cites this paper
• Bone fracture healing: perspectives according to molecular basis

  2020cites this paper
• [Numerical simulation of fracture healing].

  2020cites this paper
• Computational Approach of the Cortical Bone Mechanical Behavior Based on an Elastic Viscoplastic Damageable Constitutive Model

  2020cites this paper
• The status and challenges of replicating the mechanical properties of connective tissues using additive manufacturing.

  2020cites this paper
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  2020cites this paper
• Variable Fixation Technology Provides Rigid as Well as Progressive Dynamic Fixation: A Biomechanical Investigation.

  2020cites this paper
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  2020cites this paper
• Effects of dynamic loading on fracture healing under different locking compression plate configurations: A finite element study.

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
• A probabilistic-based approach for computational simulation of bone fracture healing

  2019cites this paper
• Effect of initial micro-movement of a fracture gap fastened by composite prosthesis on bone healing

  2019cites this paper
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  2019cites this paper
• RETRACTED ARTICLE: Effect of miR-181a-3p on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting BMP10

  2019cites this paper
• Mesenchymal stem cells for cartilage repair in osteoarthritis

  2018cites this paper
• Comparison Between Mono-And Bi-Cortical Pins Of Unilateral-Uniplanar External Fixator In Tibial Diaphyseal Fracture Healing: Numerical Investigations

  year unknowncites this paper
• The American College of Foot and Ankle Surgeons (cid:1) Clinical Consensus Statement

  year unknowncites this paper