Towards complete identification of allergens in Jack Jumper (Myrmecia pilosula) ant venom and their clinical relevance: An immunoproteomic approach

T. Wanandy,R. Wilson,D. Gell,H. Rose,N. Gueven,N. Davies,S. Brown,M. Wiese

Published 2018 in Clinical and Experimental Allergy

ABSTRACT

The venomous stings of Jack Jumper ant (JJA; species of the Myrmecia pilosula taxonomic group) are a significant public health issue in parts of south‐eastern and south‐western Australia, causing anaphylaxis in approximately 3% of the population. Three allergenic peptides, Myr p 1, Myr p 2 and Myr p 3, and one histamine‐releasing peptide, pilosulin 5, have been fully described, but there are at least 5 additional high molecular weight IgE‐binding components that have not been identified.

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