A review on melatonin action as therapeutic agent in cancer

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Frontiers in Biology

• Publication date

  2018-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s11515-018-1503-5
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• The effect of melatonin supplementation on the quality of sleep and weight status in postmenopausal women

  2014cited by this paper
• Seasonal Affective Disorder (SAD)

  2014cited by this paper
• Circadian Rhythm Abnormalities

  2013cited by this paper
• Melatonin and mitochondrial dysfunction in the central nervous system.

  2013cited by this paper
• Tryptophan metabolism: entering the field of aging and age-related pathologies.

  2013cited by this paper
• Sleep duration and endometrial cancer risk

  2012cited by this paper
• Dietary factors and fluctuating levels of melatonin

  2012cited by this paper
• SEASONAL CHANGES EFFECTS ON THE SEROTONIN AND MELATONIN TRANSMISSION

  2011cited by this paper
• Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer

  2010cited by this paper
• Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells

  2010cited by this paper
• International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

  2010cited by this paper
• Melatonin, sleep disturbance and cancer risk.

  2009cited by this paper
• Urinary 6-sulfatoxymelatonin levels and risk of breast cancer in postmenopausal women.

  2008cited by this paper
• Suprachiasmatic nucleus and melatonin

  2008cited by this paper
• Sleep duration, melatonin and breast cancer among Chinese women in Singapore.

  2008cited by this paper
• Physiological effects of melatonin: role of melatonin receptors and signal transduction pathways.

  2008cited by this paper
• The influence of melatonin and N-acetylcysteine in δ-aminolevulinic acid and lead induced genotoxicity in lymphocytes in vitro

  2007cited by this paper
• One molecule, many derivatives: A never‐ending interaction of melatonin with reactive oxygen and nitrogen species?

  2007cited by this paper
• Seasonal and diurnal melatonin production in exercising sled dogs.

  2007cited by this paper
• The mammalian pineal gland: known facts, unknown facets.

  2007cited by this paper
• Diurnal and circadian rhythms in melatonin synthesis in the turkey pineal gland and retina.

  2006cited by this paper
• Complementary and alternative medicines patients are talking about: melatonin.

  2006cited by this paper
• Estrogen-signaling pathway: a link between breast cancer and melatonin oncostatic actions.

  2006cited by this paper
• Antioxidative protection by melatonin: multiplicity of mechanisms from radical detoxification to radical avoidance.

  2005cited by this paper
• Putting cancer to sleep at night

  2005cited by this paper
• Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase.

  2005cited by this paper
• Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta‐analysis

  2005cited by this paper
• The basic physiology and pathophysiology of melatonin.

  2005cited by this paper
• Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin.

  2004cited by this paper
• Impaired sleep and rhythms in persons with cancer.

  2004cited by this paper
• A prospective study of sleep duration and mortality risk in women.

  2004cited by this paper
• Sleep associated regulation of T helper 1/T helper 2 cytokine balance in humans.

  2004cited by this paper
• Seasonal affective disorder: a vestigial evolutionary advantage?

  2004cited by this paper
• Melatonin and breast cancer: a prospective study.

  2004cited by this paper
• Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin

  2003cited by this paper
• Depression and cancer: mechanisms and disease progression.

  2003cited by this paper
• Natural mechanisms protecting against cancer.

  2003cited by this paper
• Diurnal rhythm of melatonin in young calves and intake of melatonin in milk

  2003cited by this paper
• Melatonin Protects Against Oxidative Stress Caused by δ-Aminolevulinic Acid: Implications for Cancer Reduction

  2002cited by this paper
• MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells.

  2002cited by this paper
• Melatonin: from basic research to cancer treatment clinics.

  2002cited by this paper
• Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy.

  2002cited by this paper
• Melatonin-immune system relationships.

  2002cited by this paper
• Does melatonin induce apoptosis in MCF‐7 human breast cancer cells in vitro?

  2002cited by this paper
• Melatonin prevents δ-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+

  2001cited by this paper
• Anticarcinogenic actions of melatonin which involve antioxidative processes: comparison with other antioxidants.

  2001cited by this paper
• Light in the Built Environment: Potential role of Circadian Disruption in Endocrine Disruption and Breast Cancer

  2001cited by this paper
• Comparative pharmacological studies of melatonin receptors: MT1, MT2 and MT3/QR2. Tissue distribution of MT3/QR2 .

  2001cited by this paper
• Melatonin in psychiatric disorders: a review on the melatonin involvement in psychiatry.

  2001cited by this paper
• Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland.

  2000cited by this paper
• [Effects of biorhythm regulator melatonin on DNA synthesis in short-term cultures of human malignant tumors].

  2000cited by this paper
• Differential responsiveness of MCF‐7 human breast cancer cell line stocks to the pineal hormone, melatonin

  2000cited by this paper
• Inhibitory effect of melatonin on 7, 12-dimethylbenz[a]anthracene-induced carcinogenesis of the uterine cervix and vagina in mice and mutagenesis in vitro.

  2000cited by this paper
• Differential growth inhibitory effect of melatonin on two endometrial cancer cell lines

  2000cited by this paper
• Melatonin and colon carcinogenesis. III. Effect of melatonin on proliferative activity and apoptosis in colon mucosa and colon tumors induced by 1,2-dimethylhydrazine in rats.

  2000cited by this paper
• Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population.

  2000cited by this paper
• Melatonin‐induced inhibition of proliferation and G1/S cell cycle transition delay of human choriocarcinoma JAr cells: Possible involvement of MT2 (MEL1B) receptor

  1999cited by this paper
• Melatonin receptors in PC3 human prostate tumor cells

  1999cited by this paper
• Melatonin administration in tumor-bearing mice (intact and pinealectomized) in relation to stress, zinc, thymulin and IL-2.

  1999cited by this paper
• Effects of melatonin on N-nitroso-N-methylurea-induced carcinogenesis in rats and mutagenesis in vitro (Ames test and COMET assay).

  1999cited by this paper
• Melatonin increases p53 and p21WAF1 expression in MCF-7 human breast cancer cells in vitro.

  1999cited by this paper
• Melatonin and colon carcinogenesis. II. Intestinal melatonin-containing cells and serum melatonin level in rats with 1,2-dimethylhydrazine-induced colon tumors.

  1999cited by this paper
• The oncostatic action of melatonin in an ovarian carcinoma cell line

  1999cited by this paper
• Melatonin has no effect on the growth, morphology or cell cycle of human breast cancer (MCF-7), cervical cancer (HeLa), osteosarcoma (MG-63) or lymphoblastoid (TK6) cells.

  1998cited by this paper
• Melatonin's growth-inhibitory effect on hepatoma AH 130 in the rat.

  1998cited by this paper
• The role of oxidative stress in chemical carcinogenesis.

  1998cited by this paper
• Humoral Regulation of Sleep.

  1998cited by this paper
• Influence of melatonin on invasive and metastatic properties of MCF-7 human breast cancer cells.

  1998cited by this paper
• Melatonin in humans.

  1997cited by this paper
• Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats.

  1997cited by this paper
• Low dose melatonin improves sleep in healthy middle-aged subjects

  1996cited by this paper
• Melatonin inhibits DNA synthesis in MCF-7 human breast cancer cells in vitro.

  1996cited by this paper
• Modulation of estrogen receptor mRNA expression by melatonin in MCF-7 human breast cancer cells.

  1994cited by this paper
• Interaction between melatonin and estradiol on morphological and morphometric features of MCF‐7 human breast cancer cells

  1994cited by this paper
• Melatonin and cortisol circadian secretion during ethanol withdrawal in chronic alcoholics.

  1994cited by this paper
• Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin.

  1993cited by this paper
• Antiproliferative effect of pineal indoles on cultured tumor cell lines

  1993cited by this paper
• Melatonin rhythm in human milk.

  1993cited by this paper
• Breast cancer: a model system for studying the neuroendocrine role of pineal melatonin in oncology.

  1992cited by this paper
• Melatonin and 6-sulfatoxymelatonin circadian rhythms in serum and urine of primary prostate cancer patients: evidence for reduced pineal activity and relevance of urinary determinations.

  1992cited by this paper
• The therapeutic potential for tryptophan and melatonin: possible roles in depression, sleep, Alzheimer's disease and abnormal aging.

  1990cited by this paper
• Dietary carcinogens, environmental pollution, and cancer: Some misconceptions

  1990cited by this paper
• Stage‐dependent depression of melatonin in patients with primary breast cancer. Correlation with prolactin, thyroid stimulating hormone, and steroid receptors

  1989cited by this paper
• Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture.

  1988cited by this paper
• Melatonin inhibition and pinealectomy enhancement of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in the rat.

  1981cited by this paper
• A relationship between alcohol intoxication and the disordering of brain membranes by a series of short-chain alcohols.

  1981cited by this paper
• Age- and mental health-related circadian rhythms of plasma levels of melatonin, prolactin, luteinizing hormone and follicle-stimulating hormone in man.

  1981cited by this paper
• The pineal and its hormones in the control of reproduction in mammals.

  1980cited by this paper
• Role of pineal gland in aetiology and treatment of breast cancer.

  1978cited by this paper
• John Crighton Bramwell.

  1976cited by this paper
• AGE AND ENZYME ACTIVITY IN THE HUMAN PINEAL.

  1964cited by this paper

• Neu-p11 induces NLRP3 inflammasome-induced pyroptosis via provoking NOX4-mediated mitochondrial oxidative injury in chordoma cells

  2020cites this paper
• Pharmacology of Melatonin and Its Receptors

  2020cites this paper