Giant Plasma Membrane Vesicles: An Experimental Tool for Probing the Effects of Drugs and Other Conditions on Membrane Domain Stability.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Methods in Enzymology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/bs.mie.2018.02.007PMID 29673522PMCID PMC6070695
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Effect of Solutes on the Temperature of Miscibility Transitions in Multicomponent Membranes.

  2017cited by this paper
• Protein sorting by lipid phase-like domains supports emergent signaling function in B lymphocyte plasma membranes

  2017cited by this paper
• Miscibility Transition Temperature Scales with Growth Temperature in a Zebrafish Cell Line.

  2017cited by this paper
• n-Alcohol Length Governs Shift in Lo-Ld Mixing Temperatures in Synthetic and Cell-Derived Membranes

  2017cited by this paper
• Stabilizing membrane domains antagonizes n-alcohol anesthesia

  2016cited by this paper
• Polyunsaturated Lipids Regulate Membrane Domain Stability by Tuning Membrane Order.

  2016cited by this paper
• Membrane Protein Mobility and Orientation Preserved in Supported Bilayers Created Directly from Cell Plasma Membrane Blebs.

  2016cited by this paper
• The Continuing Mystery of Lipid Rafts.

  2016cited by this paper
• Separation of liquid domains in model membranes induced with high hydrostatic pressure.

  2015cited by this paper
• Membrane Transition Temperature Determines Cisplatin Response

  2015cited by this paper
• Effects of ursolic acid on the structural and morphological behaviours of dipalmitoyl lecithin vesicles.

  2015cited by this paper
• Analytical characterization of plasma membrane-derived vesicles produced via osmotic and chemical vesiculation.

  2015cited by this paper
• Influence of High Pressure on the Bending Rigidity of Model Membranes.

  2015cited by this paper
• Growth Conditions and Cell Cycle Phase Modulate Phase Transition Temperatures in RBL-2H3 Derived Plasma Membrane Vesicles

  2015cited by this paper
• Bile Acids Modulate Signaling by Functional Perturbation of Plasma Membrane Domains*

  2013cited by this paper
• Liquid general anesthetics lower critical temperatures in plasma membrane vesicles.

  2013cited by this paper
• Adhesion stabilizes robust lipid heterogeneity in supercritical membranes at physiological temperature.

  2013cited by this paper
• Elucidating membrane structure and protein behavior using giant plasma membrane vesicles

  2012cited by this paper
• Critical Casimir forces in cellular membranes.

  2012cited by this paper
• Raft domains of variable properties and compositions in plasma membrane vesicles

  2011cited by this paper
• Lipid Rafts As a Membrane-Organizing Principle

  2010cited by this paper
• Minimal model of plasma membrane heterogeneity requires coupling cortical actin to criticality.

  2010cited by this paper
• PI(4,5)P2 degradation promotes the formation of cytoskeleton-free model membrane systems.

  2009cited by this paper
• An introduction to critical points for biophysicists; observations of compositional heterogeneity in lipid membranes.

  2009cited by this paper
• Plasma membranes are poised for activation of raft phase coalescence at physiological temperature

  2008cited by this paper
• Line tensions, correlation lengths, and critical exponents in lipid membranes near critical points.

  2008cited by this paper
• Critical fluctuations in plasma membrane vesicles.

  2008cited by this paper
• Phase studies of model biomembranes: macroscopic coexistence of Lalpha+Lbeta, with light-induced coexistence of Lalpha+Lo Phases.

  2007cited by this paper
• Lipid raft microdomains and neurotransmitter signalling

  2007cited by this paper
• Phase studies of model biomembranes: Macroscopic coexistence of Lα + Lβ, with light-induced coexistence of Lα + Lo Phases

  2007cited by this paper
• Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles

  2007cited by this paper
• Two pools of Triton X‐100‐insoluble GABAA receptors are present in the brain, one associated to lipid rafts and another one to the post‐synaptic GABAergic complex

  2007cited by this paper
• The thermodynamics of general anesthesia.

  2006cited by this paper
• Seeing spots: complex phase behavior in simple membranes.

  2005cited by this paper
• Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol.

  2003cited by this paper
• Ordered and disordered phases coexist in plasma membrane vesicles of RBL-2H3 mast cells. An ESR study.

  2003cited by this paper
• Triton promotes domain formation in lipid raft mixtures.

  2002cited by this paper
• Characterization of cholesterol-sphingomyelin domains and their dynamics in bilayer membranes.

  2001cited by this paper
• Effects of membrane cholesterol on the sensitivity of the GABA(A) receptor to GABA in acutely dissociated rat hippocampal neurones.

  2001cited by this paper
• General Anesthetic Potencies of a Series of Propofol Analogs Correlate with Potency for Potentiation of γ-Aminobutyric Acid (GABA) Current at the GABAA Receptor but Not with Lipid Solubility

  2001cited by this paper
• Lipid rafts reconstituted in model membranes.

  2001cited by this paper
• General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility.

  2001cited by this paper
• Quantitative analysis of phospholipids in functionally important membrane domains from RBL-2H3 mast cells using tandem high-resolution mass spectrometry.

  1999cited by this paper
• Functional rafts in cell membranes

  1997cited by this paper
• Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior.

  1994cited by this paper
• The effect of anaesthetics on the dynamic heterogeneity of lipid membranes.

  1993cited by this paper
• Anesthetics Affect Membrane Heterogeneity a

  1991cited by this paper
• Cholesterol-induced fluid-phase immiscibility in membranes.

  1991cited by this paper
• Stereospecific effects of inhalational general anesthetic optical isomers on nerve ion channels.

  1991cited by this paper
• Is the Mechanism of General Anesthesia Related to Lipid Membrane Spontaneous Curvature? a

  1991cited by this paper
• Mechanisms of general anesthesia.

  1990influential reference
• Phase equilibria of cholesterol/dipalmitoylphosphatidylcholine mixtures: 2H nuclear magnetic resonance and differential scanning calorimetry.

  1990cited by this paper
• Nonanesthetic alcohols dissolve in synaptic membranes without perturbing their lipids.

  1989cited by this paper
• Phase equilibria in the phosphatidylcholine-cholesterol system.

  1987cited by this paper
• Partitioning of long-chain alcohols into lipid bilayers: implications for mechanisms of general anesthesia.

  1986influential reference
• Structural studies on the membrane-bound immunoglobulin E-receptor complex. 1. Characterization of large plasma membrane vesicles from rat basophilic leukemia cells and insertion of amphipathic fluorescent probes.

  1983cited by this paper
• Molecular mechanisms of general anaesthesia

  1982cited by this paper
• Molecular mechanisms of general anaesthesia

  1981influential reference
• Antagonism between high pressure and anesthetics in the thermal phase-transition of dipalmitoyl phosphatidylcholine bilayer.

  1979cited by this paper
• Effect of anesthetics and pressure on the thermotropic behavior of multilamellar dipalmitoylphosphatidylcholine liposomes.

  1978cited by this paper
• Nuclear magnetic resonance studies of the interaction of general anesthetics with 1,2-dihexadecyl-sn-glycero-3-phosphorylcholine bilayer.

  1976cited by this paper
• Plasma membrane vesiculation: a new technique for isolation of plasma membranes.

  1976cited by this paper
• The antagonistic effect of an inhalation anesthetic and high pressure on the phase diagram of mixed dipalmitoyl-dimyristoylphosphatidylcholine bilayers.

  1975cited by this paper
• Lateral phase separation in phospholipid membranes.

  1973cited by this paper
• The membrane actions of anesthetics and tranquilizers.

  1972cited by this paper
• The membrane actions of anesthetics and tranquilizers.

  1972cited by this paper
• Some Physical Mechanisms in Narcosis.

  1954cited by this paper
• Zur Theorie der Alkoholnarkose

  1899cited by this paper

• Cholesterol promotes the formation of dimers and oligomers of the receptor tyrosine kinase ROR1

  2025cites this paper
• Cholesterol promotes the formation of dimers and oligomers of the receptor tyrosine kinase ROR1

  2025cites this paper
• Experimentally Determined Shapes of Plasma Membrane Vesicles, Phosphatidylcholine (PC), and PC-Cholesterol Vesicles: Vesicle Deflation Analysis Using Confocal Microscopy.

  2025cites this paper
• A Versatile GPMV-Imaging Platform for Quantitative Analysis of Receptor Binding and Membrane Fusion

  2025cites this paper
• Host Immune Cell Membrane Deformability Governs the Uptake Route of Malaria-Derived Extracellular Vesicles

  2025cites this paper
• Temperature dependence of membrane viscosity of ternary lipid GUV with Lo domains

  2025cites this paper
• Gelsolin traps ribosomal protein SA (RPSA) within lipid nanodomains of the plasma membrane and modulates the level of protein synthesis in the submembranous region of human skin melanoma cells.

  2025cites this paper
• Migrasome formation is initiated preferentially in tubular junctions by membrane tension

  2025cites this paper
• Intracellular pressure controls the propagation of tension in crumpled cell membranes

  2025cites this paper
• Effect of leaflet asymmetry on the stretching elasticity of lipid bilayers with phosphatidic acid

  2024cites this paper
• Lipid Peroxidation Drives Liquid–Liquid Phase Separation and Disrupts Raft Protein Partitioning in Biological Membranes

  2024cites this paper
• Shape analysis of biomimetic and plasma membrane vesicles

  2024influential citation
• Thrombomodulin (p.Cys537Stop) is released from cells by an unusual membrane insertion/leakage mechanism

  2024cites this paper
• The membrane transition strongly enhances biopolymer condensation through prewetting

  2024cites this paper
• Tensing Flipper: Photosensitized Manipulation of Membrane Tension, Lipid Phase Separation, and Raft Protein Sorting in Biological Membranes

  2024cites this paper
• CaV1.3 channel clusters characterized by live-cell and isolated plasma membrane nanoscopy

  2024cites this paper
• Shear-Induced Nonequilibrium Patterns in Lipid Bilayer Membranes Exhibiting Phase Separation.

  2024cites this paper
• Cytotoxic rhamnolipid micelles drive acute virulence in Pseudomonas aeruginosa

  2024cites this paper
• Cell Line and Media Composition Influence the Production of Giant Plasma Membrane Vesicles

  2024cites this paper
• Cytotoxic rhamnolipid micelles drive acute virulence in Pseudomonas aeruginosa

  2023cites this paper
• Tetraspanin 4 stabilizes membrane swellings and facilitates their maturation into migrasomes

  2023cites this paper
• PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection

  2023cites this paper
• Migrasome formation is initiated preferentially in tubular junctions by alternations of membrane tension or intracellular pressure

  2023cites this paper
• Lipid peroxidation drives liquid-liquid phase separation and disrupts raft protein partitioning in biological membranes

  2023cites this paper
• Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters

  2023cites this paper
• High-Content Imaging Platform to Discover Chemical Modulators of Plasma Membrane Rafts

  2022cites this paper
• Supported Natural Membranes on Microspheres for Protein-Protein Interaction Studies.

  2022cites this paper
• Tetraspanin 4 mediates migrasome formation via a two-stage mechanism

  2022cites this paper
• Transmembrane proteins tetraspanin 4 and CD9 sense membrane curvature

  2022cites this paper
• Lipidomic profiling reveals age-dependent changes in complex plasma membrane lipids that regulate neural stem cell aging

  2022cites this paper
• Forces of Change: Optical Tweezers in Membrane Remodeling Studies

  2022cites this paper
• Deciphering the Assembly of Enveloped Viruses Using Model Lipid Membranes

  2022cites this paper
• Compartmentalization of phosphatidylinositol 4,5-bisphosphate metabolism into plasma membrane liquid-ordered/raft domains

  2021cites this paper
• Single-molecule Dynamic In-Solution Inhibition Assay: A Method for Full Kinetic Profiling of Drug Candidate Binding to GPCRs in Native Membranes

  2021cites this paper
• Degranulation enhances presynaptic membrane packing, which protects NK cells from perforin-mediated autolysis

  2021cites this paper
• Recent developments in membrane curvature sensing and induction by proteins.

  2021cites this paper
• The C99 domain of the amyloid precursor protein resides in the disordered membrane phase

  2021cites this paper
• Shedding light on molecular and cellular consequences of NCX 1 palmitoylation

  2021cites this paper
• 3D RNA nanocage for encapsulation and shielding of hydrophobic biomolecules to improve the in vivo biodistribution

  2020cites this paper
• Advances in understanding and in multi-disciplinary methodology used to assess lipid regulation of signalling cascades from the cancer cell plasma membrane.

  2020cites this paper
• The C99 domain of the amyloid precursor protein is a disordered membrane phase-preferring protein

  2020cites this paper
• Fluorescence Microscopy-Based Quantitation of GLUT4 Translocation: High Throughput or High Content?

  2020cites this paper
• Topical review: Shedding light on molecular and cellular consequences of NCX1 palmitoylation.

  2020cites this paper
• Lateral heterogeneity and domain formation in cellular membranes

  2020cites this paper
• Chemical manipulations to facilitate membrane blebbing and vesicle shedding on the cellular cortex

  2020cites this paper
• Characterization of Single Protein Dynamics in Cell Plasma Membrane Derived Polymer Cushioned Lipid Bilayers

  2019cites this paper
• Understanding T cell signaling using membrane reconstitution

  2019cites this paper