The Drosophila Histone Acetyltransferase Gcn5 and Transcriptional Adaptor Ada2a Are Involved in Nucleosomal Histone H4 Acetylation

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Molecular and Cellular Biology

• Publication date

  2006-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.01401-06PMID 17030603PMCID PMC1698533
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Host Cell Factor and an Uncharacterized SANT Domain Protein Are Stable Components of ATAC, a Novel dAda2A/dGcn5-Containing Histone Acetyltransferase Complex in Drosophila

  2006influential reference
• Intimate relationship between the genes of two transcriptional coactivators, ADA2a and PIMT, of Drosophila.

  2005cited by this paper
• DTL, the Drosophila Homolog of PIMT/Tgs1 Nuclear Receptor Coactivator-interacting Protein/RNA Methyltransferase, Has an Essential Role in Development*

  2005cited by this paper
• The Histone H3 Acetylase dGcn5 Is a Key Player in Drosophila melanogaster Metamorphosis

  2005influential reference
• The Homologous Drosophila Transcriptional Adaptors ADA2a and ADA2b Are both Required for Normal Development but Have Different Functions

  2005cited by this paper
• Drosophila Ada2b Is Required for Viability and Normal Histone H3 Acetylation

  2004influential reference
• Two Drosophila Ada2 Homologues Function in Different Multiprotein Complexes

  2003influential reference
• Histone and chromatin cross-talk.

  2003cited by this paper
• The diverse functions of histone acetyltransferase complexes.

  2003cited by this paper
• Multiple Mechanistically Distinct Functions of SAGA at the PHO5 Promoter

  2003cited by this paper
• A Novel Human Ada2 Homologue Functions with Gcn5 or Brg1 To Coactivate Transcription

  2003cited by this paper
• Two Different Drosophila ADA2 Homologues Are Present in Distinct GCN5 Histone Acetyltransferase-Containing Complexes

  2003cited by this paper
• SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription

  2002cited by this paper
• Localizing transcription factors on chromatin by immunofluorescence.

  2002cited by this paper
• Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes.

  2002cited by this paper
• The Novel SLIK Histone Acetyltransferase Complex Functions in the Yeast Retrograde Response Pathway

  2002cited by this paper
• Differential Requirement of SAGA Components for Recruitment of TATA-Box-Binding Protein to Promoters In Vivo

  2002cited by this paper
• Role of the Ada2 and Ada3 Transcriptional Coactivators in Histone Acetylation*

  2002cited by this paper
• Histone H3 specific acetyltransferases are essential for cell cycle progression.

  2001cited by this paper
• Transcriptional adaptor and histone acetyltransferase proteins in Arabidopsis and their interactions with CBF1, a transcriptional activator involved in cold-regulated gene expression.

  2001cited by this paper
• The many HATs of transcription coactivators.

  2000cited by this paper
• Two Novel Drosophila TAFIIs Have Homology with Human TAFII30 and Are Differentially Regulated during Development

  2000cited by this paper
• Acetylation of Histones and Transcription-Related Factors

  2000cited by this paper
• The Yeast Histone Acetyltransferase A2 Complex, but Not Free Gcn5p, Binds Stably to Nucleosomal Arrays*

  2000cited by this paper
• Expanded Lysine Acetylation Specificity of Gcn5 in Native Complexes*

  1999cited by this paper
• Interplay between chromatin modifying and remodeling complexes in transcriptional regulation.

  1999cited by this paper
• A Human SPT3-TAFII31-GCN5-L Acetylase Complex Distinct from Transcription Factor IID*

  1998cited by this paper
• The Gcn5·Ada Complex Potentiates the Histone Acetyltransferase Activity of Gcn5*

  1998cited by this paper
• Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase

  1998cited by this paper
• Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

  1997cited by this paper
• Identification of Native Complexes Containing the Yeast Coactivator/Repressor Proteins NGG1/ADA3 and ADA2*

  1997cited by this paper
• Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5

  1996cited by this paper
• Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation.

  1996cited by this paper
• Characterization of Physical Interactions of the Putative Transcriptional Adaptor, ADA2, with Acidic Activation Domains and TATA-binding Protein (*)

  1995cited by this paper
• Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors.

  1994cited by this paper
• Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains.

  1992cited by this paper

• Acetylation-Mediated Epigenetic Consequences for Biological Control and Cancer.

  2025cites this paper
• ATAC and SAGA histone acetyltransferase modules facilitate transcription factor binding to nucleosomes independent of their acetylation activity

  2024cites this paper
• DNA double-strand break movement in heterochromatin depends on the histone acetyltransferase dGcn5

  2024cites this paper
• Exploring the versatility of zygotic genome regulators: A comparative and functional analysis.

  2024cites this paper
• ATAC and SAGA coactivator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct

  2023cites this paper
• SAGA Complex Subunit Hfi1 Is Important in the Stress Response and Pathogenesis of Cryptococcus neoformans

  2023cites this paper
• ATAC and SAGA histone acetyltransferase modules facilitate transcription factor binding to nucleosomes in an acetylation independent manner

  2023cites this paper
• Acetylation in pathogenesis: Revealing emerging mechanisms and therapeutic prospects.

  2023cites this paper
• ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct

  2023cites this paper
• Unraveling the Biology of Epithelioid Hemangioendothelioma, a TAZ–CAMTA1 Fusion Driven Sarcoma

  2022cites this paper
• The Gcn5 complexes in Drosophila as a model for metazoa.

  2020cites this paper
• What do the structures of GCN5-containing complexes teach us about their function?

  2020cites this paper
• Hat1 acetylates histone H4 and modulates the transcriptional program in Drosophila embryogenesis

  2019cites this paper
• Characterization of a metazoan ADA acetyltransferase complex

  2019cites this paper
• MYC—Master Regulator of the Cancer Epigenome and Transcriptome

  2017cites this paper
• Sharing the SAGA.

  2017cites this paper
• The Spliceosomal Protein SF3B5 is a Novel Component of Drosophila SAGA that Functions in Gene Expression Independent of Splicing.

  2016cites this paper
• dTAF10- and dTAF10b-Containing Complexes Are Required for Ecdysone-Driven Larval-Pupal Morphogenesis in Drosophila melanogaster

  2015cites this paper
• Acetylations of Ftz-F1 and histone H4K5 are required for the fine-tuning of ecdysone biosynthesis during Drosophila metamorphosis.

  2015cites this paper
• Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5*

  2015cites this paper
• Characterization of the MYST histone acetyltransferase Mof2 in Drosophila melanogaster

  2015cites this paper
• The Drosophila Helicase Maleless (MLE) is Implicated in Functions Distinct From its Role in Dosage Compensation*

  2015influential citation
• Exploring the role of nuclear phosphatases and their associated protein in cell growth and development

  2014cites this paper
• Prenatal stress-induced programming of genome-wide promoter DNA methylation in 5-HTT-deficient mice

  2014cites this paper
• Analysis of chromatin targeting modules in the chromatin remodelling enzyme NURF

  2014cites this paper
• MYC cofactors: molecular switches controlling diverse biological outcomes.

  2014cites this paper
• Analysis of the mechanism by which dADA2 factors contribute to the specificity of dSAGA and dATAC histone acetyltransferase complexes

  2013influential citation
• A dSAGA specifikus hiszton acetiláció génműködés szabályozásban betöltött funkciójának vizsgálata

  2013cites this paper
• PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth

  2013cites this paper
• The C‐terminal domains of ADA2 proteins determine selective incorporation into GCN5‐containing complexes that target histone H3 or H4 for acetylation

  2012cites this paper
• Induced Gene Expression Is Associated with Acetylation of Histone H 3 Lysine 23 in Drosophila melanogaster Permalink

  2012cites this paper
• N-Myc and GCN5 Regulate Significantly Overlapping Transcriptional Programs in Neural Stem Cells

  2012cites this paper
• Epigenetic regulation and epigenomics

  2012cites this paper
• Caractérisation fonctionnelle de l'activité de l'histone acétyltransférase GCN5 au sein des complexes ATAC et SAGA chez l'homme

  2012influential citation
• Ecdysone Induced Gene Expression Is Associated with Acetylation of Histone H3 Lysine 23 in Drosophila melanogaster

  2012cites this paper
• Histone modification in Drosophila.

  2012cites this paper
• Histone modifiers in cancer: friends or foes?

  2011cites this paper
• The role of transcriptional coactivator ADA2b in Arabidopsis abiotic stress responses

  2011cites this paper
• Arabidopsis thaliana transcriptional co-activators ADA2b and SGF29a are implicated in salt stress responses

  2011cites this paper
• Transcriptional analysis of the histone acetylation and deacetylation in Candida albicans

  2011cites this paper
• Genes of the Ecdysone Biosynthesis Pathway Are Regulated by the dATAC Histone Acetyltransferase Complex in Drosophila

  2010influential citation
• The ATAC acetyl transferase complex controls mitotic progression by targeting non‐histone substrates

  2010cites this paper
• The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes

  2010influential citation
• Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq

  2010cites this paper
• The ATAC acetyltransferase complex coordinates MAP kinases to regulate JNK target genes.

  2010cites this paper
• Histone acetylation, acetyltransferases, and ataxia--alteration of histone acetylation and chromatin dynamics is implicated in the pathogenesis of polyglutamine-expansion disorders.

  2010cites this paper
• A new role of ATAC-HAT in dosage compensation.

  2010cites this paper
• Altered Histone 4 K12 Acetylation is Associated with Age Dependent Memory Impairment in Mice

  2010cites this paper
• The SAGA Subunit Ada2 Functions in Transcriptional Silencing

  2009cites this paper
• Functional analysis of Drosophila melanogaster histone H4 specific acetylase complex and its role in regulating chromatin structure

  2009cites this paper
• The loss of histone H3 lysine 9 acetylation due to dSAGA-specific dAda2b mutation influences the expression of only a small subset of genes

  2009cites this paper
• GAL4 induces transcriptionally active puff in the absence of dSAGA- and ATAC-specific chromatin acetylation in the Drosophila melanogaster polytene chromosome

  2009influential citation
• A New Coactivator Function for Zac1's C2H2 Zinc Finger DNA-Binding Domain in Selectively Controlling PCAF Activity

  2008cites this paper
• The STAGA Subunit ADA2b Is an Important Regulator of Human GCN5 Catalysis

  2008influential citation
• Dynamics of histone H4 acetylation during the cell cycle

  2008cites this paper
• ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding

  2008cites this paper
• The Drosophila NURF remodelling and the ATAC histone acetylase complexes functionally interact and are required for global chromosome organization

  2008cites this paper
• Loss of ATAC-specific acetylation of histone H4 at Lys12 reduces binding of JIL-1 to chromatin and phosphorylation of histone H3 at Ser10

  2008cites this paper
• The STAGA Subunit ADA 2 b Is an Important Regulator of Human GCN 5 Catalysis †

  2008influential citation
• The Double-Histone-Acetyltransferase Complex ATAC Is Essential for Mammalian Development

  2008influential citation
• Human ATAC Is a GCN5/PCAF-containing Acetylase Complex with a Novel NC2-like Histone Fold Module That Interacts with the TATA-binding Protein*

  2008cites this paper
• Transcriptional Adaptor ADA3 of Drosophila melanogaster Is Required for Histone Modification, Position Effect Variegation, and Transcription

  2007cites this paper
• The Drosophila jumonji gene encodes a JmjC‐containing nuclear protein that is required for metamorphosis

  2007cites this paper
• Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer.

  2007cites this paper
• Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation

  2007influential citation
• Positive Cross-Regulatory Loop Ties GATA-3 to Estrogen Receptor α Expression in Breast Cancer

  2007cites this paper
• Loss of Gcn5 Acetyltransferase Activity Leads to Neural Tube Closure Defects and Exencephaly in Mouse Embryos

  2007cites this paper
• DNA Double-Strand Break Movement in Heterochromatin Depends on the Drosophila Histone Acetyltransferase Gcn5.

  year unknowncites this paper
• The Gcn5 Complexes in Drosophila As A Model for Metazoa The Gcn5 Complexes in Drosophila As A Model for Metazoa

  year unknowncites this paper