Electrochemical Hydrogel Lithography of Calcium-Alginate Hydrogels for Cell Culture

Here we propose a novel electrochemical lithography methodology for fabricating calcium-alginate hydrogels having controlled shapes. We separated the chambers for Ca2+ production and gel formation with alginate with a semipermeable membrane. Ca2+ formed in the production chamber permeated through the membrane to fabricate a gel structure on the membrane in the gel formation chamber. When the calcium-alginate hydrogels were modified with collagen, HepG2 cells proliferated on the hydrogels. These results show that electrochemical hydrogel lithography is useful for cell culture.

• Publication year

  2016

• Venue

  Materials

• Publication date

  2016-08-31

• Fields of study

  Biology, Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.3390/ma9090744PMID 28773863PMCID 5457093
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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