Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Cell Stem Cell

• Publication date

  2017-12-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.stem.2017.11.003PMID 29198940PMCID PMC5975960
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness.

  2017cited by this paper
• Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3+ regulatory T cells in murine colon cancer

  2017cited by this paper
• Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

  2016cited by this paper
• Heterogeneity of the bone marrow niche

  2016cited by this paper
• Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation.

  2016cited by this paper
• Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation

  2016cited by this paper
• Hematopoietic Stem Cell Niches Produce Lineage-Instructive Signals to Control Multipotent Progenitor Differentiation.

  2016cited by this paper
• The Orphan Nuclear Receptor NR4A1 Specifies a Distinct Subpopulation of Quiescent Myeloid‐Biased Long‐Term HSCs

  2015cited by this paper
• Schinke C, Giricz O, Li W, et al. IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells. Blood. 2015;125(20):3144-3152.

  2015cited by this paper
• Fundamental properties of unperturbed haematopoiesis from stem cells in vivo

  2015cited by this paper
• Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells.

  2015cited by this paper
• IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells.

  2015cited by this paper
• PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS A lack of secretory leukocyte protease inhibitor ( SLPI ) causes defects in granulocytic differentiation

  2014cited by this paper
• The bone marrow niche for haematopoietic stem cells

  2014cited by this paper
• Cytotoxic CD8+ T cells stimulate hematopoietic progenitors by promoting cytokine release from bone marrow mesenchymal stromal cells.

  2014cited by this paper
• Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells

  2014cited by this paper
• Stem and Progenitor Cell Subsets Are Affected by JAK2 Signaling and Can Be Monitored by Flow Cytometry

  2014cited by this paper
• Molecular regulation of stem cell quiescence

  2013cited by this paper
• Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells.

  2013cited by this paper
• Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

  2013cited by this paper
• Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

  2013cited by this paper
• Megakaryocytes regulate hematopoietic stem cell quiescence via Cxcl4 secretion

  2013cited by this paper
• Histamine production by human neutrophils

  2013cited by this paper
• Toll-Like Receptor 4/Stem Cell Antigen 1 Signaling Promotes Hematopoietic Precursor Cell Commitment to Granulocyte Development during the Granulopoietic Response to Escherichia coli Bacteremia

  2013cited by this paper
• CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age.

  2013cited by this paper
• SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors.

  2013cited by this paper
• Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis

  2012cited by this paper
• Combinatorial roles for histamine H1‐H2 and H3‐H4 receptors in autoimmune inflammatory disease of the central nervous system

  2012cited by this paper
• IFNγ induces monopoiesis and inhibits neutrophil development during inflammation.

  2011cited by this paper
• Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response

  2011cited by this paper
• Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer.

  2011cited by this paper
• The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow

  2011cited by this paper
• Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease.

  2011cited by this paper
• Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

  2010cited by this paper
• Stem cells and the aging hematopoietic system.

  2010cited by this paper
• Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

  2010cited by this paper
• Awakening dormant haematopoietic stem cells

  2010cited by this paper
• Histamine deficiency promotes inflammation-associated carcinogenesis through reduced myeloid maturation and accumulation of CD11b+Ly6G+ immature myeloid cells

  2010cited by this paper
• ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays.

  2009cited by this paper
• Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis.

  2009cited by this paper
• Rho GTPase Cdc42 is essential for B-lymphocyte development and activation.

  2008cited by this paper
• Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family.

  2008cited by this paper
• Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis

  2007cited by this paper
• Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia: results of a randomized phase 3 trial.

  2006cited by this paper
• Identification of a homozygous deletion in the AP3B1 gene causing Hermansky-Pudlak syndrome, type 2.

  2006cited by this paper
• Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment.

  2006cited by this paper
• Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors

  2005cited by this paper
• S100A8 induction in keratinocytes by ultraviolet A irradiation is dependent on reactive oxygen intermediates.

  2003cited by this paper
• Gene expression analysis of purified hematopoietic stem cells and committed progenitors.

  2003cited by this paper
• Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

  1999cited by this paper
• Controlling the false discovery rate: a practical and powerful approach to multiple testing

  1995cited by this paper

• IFN alpha signaling drives hematopoietic stem cells malfunction under acute inflammation.

  2025cites this paper
• Chronic stress promotes pancreatic ductal adenocarcinoma progression via complement C5a-recruited myeloid-derived suppressor cells

  2025cites this paper
• Histamine Deficiency Inhibits Lymphocyte Infiltration in the Lacrimal Gland of Aged Mice

  2025cites this paper
• Genes with altered expression by 5-Aza treatment in myeloid leukemia cells through methylation in intron 1.

  2025cites this paper
• Restoring resident tissue macrophages to combat aging and cancer

  2025cites this paper
• Bone marrow neutrophil density regulates myelopoiesis during obesity and weight loss.

  2025cites this paper
• A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis.

  2025cites this paper
• Neutrophil Spatiotemporal Regulatory Networks: Dual Roles in Tumor Growth Regulation and Metastasis

  2025cites this paper
• Neutrophils in BCR::ABL1 negative MPN: Contributors or bystanders of fibrosis?

  2025cites this paper
• High fat diet feeding impairs neutrophil phagocytosis, bacterial killing, and neutrophil-induced hematopoietic regeneration.

  2025cites this paper
• New Developments in Computational Methods for CNN-Based Models-Based Blood Cell Classification

  2025cites this paper
• Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells

  2025cites this paper
• PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells

  2024cites this paper
• Effect of bone marrow niche on hematopoietic stem cells

  2024cites this paper
• Neutrophils in toxicology: a forgotten field

  2024cites this paper
• Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice

  2024cites this paper
• The role of immune cells settled in the bone marrow on adult hematopoietic stem cells

  2024cites this paper
• Histamine deficiency exacerbates cisplatin-induced ferroptosis in cochlea hair cells of HDC knockout mice.

  2024cites this paper
• Optimization-based convolutional neural model for the classification of white blood cells

  2024cites this paper
• Interactions between MDSCs and the Autonomic Nervous System: Opportunities and Challenges in Cancer Neuroscience.

  2024cites this paper
• Immature myeloid cells are indispensable for intestinal regeneration post irradiation injury

  2023cites this paper
• Role of histamine-mediated macrophage differentiation in clearance of metastatic bacterial infection

  2023cites this paper
• Microbial-Dependent Recruitment of Immature Myeloid Cells Promotes Intestinal Regeneration

  2023influential citation
• Hematopoietic stem cells undergo a lymphoid to myeloid switch in early stages of emergency granulopoiesis

  2023cites this paper
• Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells

  2023cites this paper
• Neutrophil diversity in inflammation and cancer

  2023influential citation
• Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity

  2023cites this paper
• IL-33 induces histidine decarboxylase, especially in c-kit^+ cells and mast cells, and roles of histamine include negative regulation of IL-33-induced eosinophilia

  2023cites this paper
• Translocation of Helicobacter hepaticus synergizes with myeloid-derived suppressor cells and contributes to breast carcinogenesis

  2022cites this paper
• The Fetal Hematopoietic Niche: Components and Mechanisms for Hematopoietic Stem Cell Emergence and Expansion

  2022cites this paper
• Histamine Signaling Is Essential for Tissue Macrophage Differentiation and Suppression of Bacterial Overgrowth in the Stomach

  2022cites this paper
• Disruption of histamine/H1R-STAT3-SLC7A11 axis exacerbates doxorubicin-induced cardiac ferroptosis.

  2022cites this paper
• Central nervous system regeneration in ascidians: cell migration and differentiation

  2022cites this paper
• Sex-specific niche signaling contributes to sexual dimorphism following stem cell transplantation

  2022cites this paper
• Molecular regulation of hematopoietic stem cell quiescence

  2022cites this paper
• Neutrophil Migratory Patterns: Implications for Cardiovascular Disease

  2022cites this paper
• Histamine receptor 2 blockade selectively impacts B and T cells in healthy subjects

  2021cites this paper
• Histidine decarboxylase deficiency inhibits NBP-induced extramedullary hematopoiesis by modifying bone marrow and spleen microenvironments

  2021cites this paper
• Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1

  2021cites this paper
• Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cells

  2021cites this paper
• Obesity-induced inflammation: The impact of the hematopoietic stem cell niche

  2021cites this paper
• Histamine can be Formed and Degraded in the Human and Mouse Heart

  2021influential citation
• CD63 acts as a functional marker in maintaining hematopoietic stem cell quiescence through supporting TGFβ signaling in mice

  2021cites this paper
• Toll-Like Receptors in Stem/Progenitor Cells.

  2021cites this paper
• Prmt1 upregulated by Hdc deficiency aggravates acute myocardial infarction via NETosis

  2021cites this paper
• Histamine Deficiency Promotes Myofibroblasts Transformation from HDC-Expressing CD11b+ Myeloid Cells in Injured Hearts Post Myocardial Infarction

  2021cites this paper
• Loss of H2R Signaling Disrupts Neutrophil Homeostasis and Promotes Inflammation-Associated Colonic Tumorigenesis in Mice

  2021cites this paper
• Myeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress and life-long persistence

  2021cites this paper
• Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2.

  2020cites this paper
• Imaging and spatial analysis of hematopoietic stem cell niches

  2020cites this paper
• Induction of developmental hematopoiesis mediated by transcription factors and the hematopoietic microenvironment

  2020cites this paper
• Stem cell quiescence and its clinical relevance

  2020cites this paper
• Acute Intestinal Inflammation Depletes/Recruits Histamine-Expressing Myeloid Cells From the Bone Marrow Leading to Exhaustion of MB-HSCs

  2020cites this paper
• Molecular and cellular mechanisms of aging in hematopoietic stem cells and their niches

  2020cites this paper
• Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage

  2020cites this paper
• Histamine receptor 1 is expressed in leukaemic cells and affects differentiation sensitivity

  2020cites this paper
• Androgen Receptor Signaling Positively Regulates Monocytic Development

  2020cites this paper
• The complexity of neutrophils in health and disease: Focus on cancer

  2020cites this paper
• Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow.

  2020cites this paper
• Histidine decarboxylase-expressing PMN-MDSC-derived TGF-β1 promotes the epithelial-mesenchymal transition of metastatic lung adenocarcinoma.

  2020cites this paper
• Hdc-expressing myeloid-derived suppressor cells promote basal-like transition and metastasis of breast cancer.

  2020cites this paper
• Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage

  2020cites this paper
• Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cell

  2020cites this paper
• The bone marrow hematopoietic niche and its adaptation to infection.

  2020cites this paper
• Famotidine Use Is Associated With Improved Clinical Outcomes in Hospitalized COVID-19 Patients: A Propensity Score Matched Retrospective Cohort Study

  2020cites this paper
• Protection of hematopoietic stem cells from stress-induced exhaustion and aging.

  2020cites this paper
• Histamine and histidine decarboxylase: Immunomodulatory functions and regulatory mechanisms

  2020cites this paper
• Famotidine Use is Associated with Improved Clinical Outcomes in Hospitalized COVID-19 Patients: A Retrospective Cohort Study

  2020cites this paper
• Is Avoiding Stem Cell Exhaustion the New Therapeutic Approach in Colitis?

  2020cites this paper
• Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells

  2020cites this paper
• Histamine deficiency facilitates coronary microthrombosis after myocardial infarction by increasing neutrophil‐platelet interactions

  2020cites this paper
• Leukocyte Trafficking and Regulation of Murine Hematopoietic Stem Cells and Their Niches

  2019influential citation
• The Hematopoietic Stem Cell Niche in Leukemia Predisposition

  2019cites this paper
• Environmental Influences on Clonal Hematopoiesis.

  2019cites this paper
• Lipopolysaccharide-induced expansion of histidine decarboxylase-expressing Ly6G+ myeloid cells identified by exploiting histidine decarboxylase BAC-GFP transgenic mice

  2019cites this paper
• Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l

  2019cites this paper
• Mitochondrial metabolism and the maintenance of hematopoietic stem cell quiescence.

  2019cites this paper
• Role of Toll-Like Receptors in Actuating Stem/Progenitor Cell Repair Mechanisms: Different Functions in Different Cells

  2019cites this paper
• Neutrophils as regulators of the hematopoietic niche.

  2019cites this paper
• Heterogeneity of neutrophils

  2019cites this paper
• Haematopoietic stem cell activity and interactions with the niche

  2019cites this paper
• Hematopoietic Stem Cell Heterogeneity.

  2019cites this paper
• Plasma Cells Are Obligate Effectors of Enhanced Myelopoiesis in Aging Bone Marrow.

  2019cites this paper
• Hematopoietic Hierarchy - An Updated Roadmap.

  2018cites this paper
• Niches for Hematopoietic Stem Cells and Their Progeny.

  2018cites this paper
• The Role of Interferon-Gamma in Hematopoietic Stem Cell Development, Homeostasis, and Disease

  2018cites this paper
• Dynamic Regulation of Hematopoietic Stem Cells by Bone Marrow Niches

  2018cites this paper
• Chronic immune response dysregulation in MDS pathogenesis.

  2018cites this paper
• Saving Stem Cells after Stress.

  2017cites this paper