The molecular assembly of the ionic liquid/aliphatic carboxylic acid/aliphatic amine as effective and safety transdermal permeation enhancers.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  European Journal of Pharmaceutical Sciences

• Publication date

  2016-04-30

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.ejps.2016.03.002PMID 26965004
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Azone® decreases the buccal mucosal permeation of diazepam in a concentration-dependent manner via a reservoir effect.

  2014cited by this paper
• A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material

  2014cited by this paper
• Efficient delivery and distribution in skin of chlorogenic acid and resveratrol induced by microemulsion using sucrose laurate.

  2014cited by this paper
• Pharmaceutical Salts: Solids to Liquids by Using Ionic Liquid Design

  2013cited by this paper
• Glycerosomes: a new tool for effective dermal and transdermal drug delivery.

  2013cited by this paper
• Stratum corneum drying drives vertical compression and lipid organization and improves barrier function in vitro.

  2013cited by this paper
• Claudin-5 Controls Intercellular Barriers of Human Dermal Microvascular but Not Human Umbilical Vein Endothelial Cells

  2013cited by this paper
• Development and characterization of a novel controlled release drug delivery system based on nanostructured lipid carriers gel for meloxicam.

  2013cited by this paper
• Ionic liquids as ingredients in topical drug delivery systems.

  2013cited by this paper
• Long-term safety, efficacy, and patient acceptability of the tulobuterol patch

  2013cited by this paper
• The human skin barrier is organized as stacked bilayers of fully extended ceramides with cholesterol molecules associated with the ceramide sphingoid moiety.

  2012cited by this paper
• Solid-in-oil dispersion: a novel core technology for drug delivery systems.

  2012cited by this paper
• Development of drug delivery systems for the dermal application of therapeutic DNAzymes.

  2012cited by this paper
• Transdermal delivery of the anti-rheumatic agent methotrexate using a solid-in-oil nanocarrier.

  2012cited by this paper
• Essential roles of PIKfyve and PTEN on phagosomal phosphatidylinositol 3‐phosphate dynamics

  2012cited by this paper
• Distribution of polyphenols and a surfactant component in skin during Aerosol OT microemulsion-enhanced intradermal delivery.

  2012cited by this paper
• Nanocarrier-based topical drug delivery for the treatment of skin diseases

  2012cited by this paper
• Enhanced in vitro transbuccal drug delivery of ondansetron HCl.

  2011cited by this paper
• Ammonium carbamates as highly active transdermal permeation enhancers with a dual mechanism of action.

  2011cited by this paper
• Protective effect of drug delivery systems against the enzymatic degradation of dermally applied DNAzyme.

  2011cited by this paper
• Ionic Liquids as Active Pharmaceutical Ingredients

  2011cited by this paper
• Impact of ionic liquids in environment and humans: An overview

  2010cited by this paper
• Enhanced skin delivery of genistein and other two isoflavones by microemulsion and prevention against UV irradiation-induced erythema formation.

  2010cited by this paper
• Activation and stabilization of enzymes in ionic liquids.

  2010cited by this paper
• Crystalline vs. Ionic Liquid Salt Forms of Active Pharmaceutical Ingredients: A Position Paper

  2010cited by this paper
• Recent advances of enzymatic reactions in ionic liquids

  2010cited by this paper
• Antimicrobial and antibiofilm activities of 1-alkylquinolinium bromide ionic liquids

  2010cited by this paper
• Transcutaneous immunization by a solid-in-oil nanodispersion.

  2010cited by this paper
• Infrared spectroscopic study of lipid interaction in stratum corneum treated with transdermal absorption enhancers.

  2010cited by this paper
• Ionic liquid-in-oil microemulsion as a potential carrier of sparingly soluble drug: characterization and cytotoxicity evaluation.

  2010cited by this paper
• Effect of Surfactant Mixtures on Skin Structure and Barrier Properties

  2010cited by this paper
• Vesicular carriers for dermal drug delivery

  2009cited by this paper
• Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes.

  2009cited by this paper
• Biocompatible ionic liquids: a new approach for stabilizing proteins in liquid formulation.

  2009cited by this paper
• Microemulsions with an ionic liquid surfactant and room temperature ionic liquids as polar pseudo-phase.

  2009cited by this paper
• Delivery of resveratrol, a red wine polyphenol, from solutions and hydrogels via the skin.

  2008cited by this paper
• Transdermal permeation enhancement of N-trimethyl chitosan for testosterone.

  2008cited by this paper
• Room temperature ionic liquids and their mixtures: potential pharmaceutical solvents.

  2008cited by this paper
• Transdermal drug delivery

  2008cited by this paper
• A solid-in-oil nanodispersion for transcutaneous protein delivery.

  2008cited by this paper
• Effect of ion‐pairing and enhancers on scutellarin skin permeability

  2008cited by this paper
• The third evolution of ionic liquids: active pharmaceutical ingredients

  2007cited by this paper
• A review of compliance to treatment in Alzheimer's disease: potential benefits of a transdermal patch

  2007cited by this paper
• Water-induced coacervation of alkyl carboxylic acid reverse micelles: phenomenon description and potential for the extraction of organic compounds.

  2007cited by this paper
• Effect of added ionic liquid on aqueous Triton X-100 micelles.

  2007cited by this paper
• The "in vitro" percutaneous penetration of three antioxidant compounds.

  2007cited by this paper
• Physicochemical properties and structures of room-temperature ionic liquids. 3. Variation of cationic structures.

  2006cited by this paper
• Synthesis and transdermal permeation-enhancing activity of ketone, amide, and alkane analogs of Transkarbam 12.

  2006cited by this paper
• Alteration of the Circadian Rhythm in Peak Expiratory Flow of Nocturnal Asthma Following Nighttime Transdermal β2‐adrenoceptor Agonist Tulobuterol Chronotherapy

  2005cited by this paper
• Physicochemical properties and structures of room temperature ionic liquids. 2. Variation of alkyl chain length in imidazolium cation.

  2005cited by this paper
• Adherence to medication.

  2005cited by this paper
• Esters of 6-aminohexanoic acid as skin permeation enhancers: The effect of branching in the alkanol moiety.

  2005cited by this paper
• TX-100/water/1-butyl-3-methylimidazolium hexafluorophosphate microemulsions.

  2005cited by this paper
• Transdermal drug delivery: penetration enhancement techniques.

  2005cited by this paper
• Physicochemical Properties and Structures of Room Temperature Ionic Liquids. 1. Variation of Anionic Species

  2004cited by this paper
• Infrared Spectroscopy of Aqueous Carboxylic Acids: Comparison between Different Acids and Their Salts

  2004cited by this paper
• Terpenes and the Lipid–Protein–Partitioning Theory of Skin Penetration Enhancement

  2004cited by this paper
• Anti-microbial activities of ionic liquids

  2003cited by this paper
• Application of analytical derivatizations to the quantitative and qualitative determination of fatty acids

  2002cited by this paper
• [Development of transdermal formulation of tulobuterol for the treatment of bronchial asthma].

  2002cited by this paper
• Skin permeation enhancement effect and skin irritation of saturated fatty alcohols.

  2002cited by this paper
• Ionic liquids: Innovative fluids for chemical processing

  2001cited by this paper
• Structure-activity relationship of chemical penetration enhancers in transdermal drug delivery.

  2000cited by this paper
• The 500 Dalton rule for the skin penetration of chemical compounds and drugs

  2000cited by this paper
• Comparative enhancer effects of Span20 with Tween20 and Azone on the in vitro percutaneous penetration of compounds with different lipophilicities.

  2000cited by this paper
• Structure-related aspects on water diffusivity in fatty acid-soap and skin lipid model systems.

  2000cited by this paper
• The Outermost Stratum Corneum Layer is an Effective Barrier Against Dermal Uptake of Topically Applied Micronized Titanium Dioxide

  1999cited by this paper
• Current status and future prospects of transdermal drug delivery.

  1996cited by this paper
• Current Status and Future Prospects of Transdermal Drug Delivery

  1996cited by this paper
• In vitro evaluation of a series of Azone analogs as dermal penetration enhancers. II: (Thio) amides

  1993cited by this paper
• Lipid-Protein-Partitioning theory of skin penetration enhancement

  1991cited by this paper
• Enhancing effect of pyrrolidone derivatives on transdermal penetration of phenolsulfonphthalein and indomethacin from aqueous vehicle.

  1990cited by this paper
• Action of skin penetration enhancers—the Lipid Protein Partitioning theory

  1988cited by this paper
• Effect of Azone on the percutaneous absorption of 5-fluorouracil from gels in hairless rats.

  1987cited by this paper

• Ionic liquids as transdermal drug carriers: A review of recent advancements

  2025cites this paper
• Characterization and drug solubilization of arginine-based ionic liquids - Impact of counterions and stoichiometry.

  2024cites this paper
• Improving oral absorption of tretinoin by ionic liquids technology

  2024cites this paper
• Utilizing ionic liquids as eco-friendly and sustainable carriers for delivering nucleic acids: A review on the revolutionary advancement in nano delivery systems.

  2024cites this paper
• Understanding the effects of targeted modifications on the 1 : 2 Choline And GEranate structure.

  2024cites this paper
• Ionic liquids and deep eutectic solvents for the stabilization of biopharmaceuticals: A review.

  2024cites this paper
• Ionic liquids as the effective technology for enhancing transdermal drug delivery: Design principles, roles, mechanisms, and future challenges

  2024cites this paper
• Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems

  2023influential citation
• Ionic Liquids: New Forms of Active Pharmaceutical Ingredients with Unique, Tunable Properties.

  2023cites this paper
• A Comprehensive Review on Imperative Role of Ionic Liquids in Pharmaceutical Sciences.

  2023cites this paper
• Effect of Ionic Liquid on Silver-Nanoparticle-Complexed Ganoderma applanatum and Its Topical Film Formulation

  2023cites this paper
• Novel berberine-based pharmaceutical salts with fatty acid anions: Synthesis, characterization, physicochemical properties

  2022cites this paper
• Preparation and characterization of innovative electrospun nanofibers loaded with pharmaceutically applicable ionic liquids.

  2022cites this paper
• Potential for reversing miR-634-mediated cytoprotective processes to improve efficacy of chemotherapy against oral squamous cell carcinoma

  2022cites this paper
• Ionic solvents for transdermal drug delivery

  2021cites this paper
• Molecular perspective of efficiency and safety problems of chemical enhancers: bottlenecks and recent advances

  2021cites this paper
• Nanopharmaceuticals: Principles and Applications Vol. 1

  2021cites this paper
• Augmentation of lenvatinib efficacy by topical treatment of miR-634 ointment in anaplastic thyroid cancer

  2021cites this paper
• Lidocaine as eutectic forming drug for enhanced transdermal delivery of nonsteroidal anti-inflammatory drugs

  2021cites this paper
• Progress in natural polymer engineered biomaterials for transdermal drug delivery systems

  2021cites this paper
• Ionic Liquids in Drug Delivery

  2021cites this paper
• Ionic liquids: prospects for nucleic acid handling and delivery

  2021cites this paper
• Surface-Active Ionic Liquids for Medical and Pharmaceutical Applications

  2021cites this paper
• Precautions for using  quaternary ammonium salt type surfactant on skin           

  2020cites this paper
• Ionic liquids: green and tailor-made solvents in drug delivery.

  2020cites this paper
• Novel skin permeation enhancers based on amino acid ester ionic liquid: Design and permeation mechanism.

  2020cites this paper
• Potential Application of Ionic Liquids in Pharmaceutical Dosage Forms for Small Molecule Drug and Vaccine Delivery System.

  2020cites this paper
• An Overview on Ionic Liquids: A New Frontier for Nanopharmaceuticals

  2020cites this paper
• Comparison of Ionic Liquids and Chemical Permeation Enhancers for Transdermal Drug Delivery

  2020cites this paper
• Effect of Alkyl Structure (Straight Chain/Branched Chain/Unsaturation) of C18 Fatty Acid Sodium Soap on Skin Barrier Function

  2020cites this paper
• The Role of Ionic Liquids in the Pharmaceutical Field: An Overview of Relevant Applications

  2020cites this paper
• Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment

  2020cites this paper
• Ionic Liquids as Potential and Synergistic Permeation Enhancers for Transdermal Drug Delivery

  2019cites this paper
• Design Principles of Ionic Liquids for Transdermal Drug Delivery

  2019cites this paper
• Ionic liquid-based transdermal delivery of propranolol: a patent evaluation of US2018/0169033A1.

  2019cites this paper
• Ionic Liquid-Polymer Nanoparticle Hybrid Systems as New Tools to Deliver Poorly Soluble Drugs

  2019cites this paper
• Synthesis, characterization, ecotoxicity and biodegradability evaluations of novel biocompatible surface active lauroyl sarcosinate ionic liquids.

  2019cites this paper
• STAT6 decoy oligodeoxynucleotide (ODN)-containing ointment more potently inhibits mouse skin inflammation when formulated with ionic liquid technology than as a traditional Vaseline ointment.

  2019cites this paper
• Development of cosmeceutical formulations based on mushroom extracts and their individual compounds

  2019cites this paper
• Evaluation of anionic surfactants effects on the skin barrier function based on skin permeability

  2019cites this paper
• Transdermal delivery of nobiletin using ionic liquids

  2019cites this paper
• Amorphous Ionic Liquid Strategies for Pharmaceutical Application

  2019cites this paper
• Topical agent composition containing compound having 6-deoxy-7,8-dihydro-6-oxomorphine skeleton as medicinal component

  2018cites this paper
• Influence of two choline-based ionic liquids on the solubility of caffeine

  2018cites this paper
• Oligoether Carboxylate Counterions: An Innovative Way Towards Surfactant Ionic Liquids

  2018cites this paper
• ６－デオキシ－７，８－ジヒドロ－６－オキソモルヒネ骨格を有する化合物を薬効成分とする外用剤組成物

  2018cites this paper
• Ionic liquids for addressing unmet needs in healthcare

  2018influential citation
• An emerging integration between ionic liquids and nanotechnology: general uses and future prospects in drug delivery.

  2017cites this paper
• Biological Activity of Ionic Liquids and Their Application in Pharmaceutics and Medicine.

  2017cites this paper
• Applicability of Ionic Liquids in Topical Drug Delivery Systems: A Mini Review

  2017cites this paper
• Ionic liquids as functional ingredients in drug delivery systems: solubility, permeation and cytotoxicity studies

  2017cites this paper
• Influence of bile salt on vitamin E derived vesicles involving a surface active ionic liquid and conventional cationic micelle.

  2017cites this paper
• Exploring unsaturated fatty acid cholesteryl esters as transdermal permeation enhancers

  2017cites this paper
• Hydroxycinnamic Acids and Their Derivatives: Cosmeceutical Significance, Challenges and Future Perspectives, a Review

  2017cites this paper