Signal integration on plant promoters

Gene promoters perceive numerous signals and integrate this information into a single response, the transcriptional activity of a gene. It was speculated that covalent modification of histones on the promoters might have an important function in storage and integration of signals. Using the genes for the core proteins of C4 metabolism in maize as a model, we associated the perception of specific signals with the establishment of individual histone modifications. Core elements of the histone code defined in these studies are conserved on all C4 genes and on other maize genes that respond to similar stimuli. Moreover, the code is used in independent C4 lineages. However, our data also advise caution because interpretation of histone modifications might differ dependent on the promoter position of the modification. The model provided here constitutes a starting point for genome-wide decoding of stimulus-modification pairs in epigenetic gene regulation.

• Publication year

  2013

• Venue

  Plant Signalling & Behavior

• Publication date

  2013-06-27

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.4161/psb.25389PMID 23857353PMCID 4002602
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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