Association between serotonin transporter (SERT) gene polymorphism and idiopathic pulmonary arterial hypertension: a meta-analysis and review of the literature.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Metabolism: Clinical and Experimental

• Publication date

  2013-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.metabol.2013.08.012PMID 24075737
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension.

  2013cited by this paper
• Polymorphisms in the serotonin transporter protein (SERT) gene in patients with pulmonary arterial hypertension.

  2012cited by this paper
• Polymorphisms in the serotonin transporter protein (SERT) gene in patients with pulmonary arterial hypertension.

  2012influential reference
• Inflammation, immunological reaction and role of infection in pulmonary hypertension.

  2011cited by this paper
• 5HTT Promoter Polymorphism in Idiopathic Pulmonary Arterial Hypertension

  2011cited by this paper
• The role of mitochondria in pulmonary vascular remodeling

  2010cited by this paper
• Basic Science of Pulmonary Arterial Hypertension for Clinicians: New Concepts and Experimental Therapies

  2010cited by this paper
• Sequence Variants in BMPR2 and Genes Involved in the Serotonin and Nitric Oxide Pathways in Idiopathic Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension: Relation to Clinical Parameters and Comparison with Left Heart Disease

  2009cited by this paper
• NOTCH3 SIGNALING IS REQUIRED FOR THE DEVELOPMENT OF PULMONARY ARTERIAL HYPERTENSION

  2009cited by this paper
• Updated clinical classification of pulmonary hypertension.

  2009cited by this paper
• Inflammation, growth factors, and pulmonary vascular remodeling.

  2009cited by this paper
• Updated clinical classification of pulmonary hypertension.

  2009cited by this paper
• Serotonin and pulmonary hypertension--from bench to bedside?

  2009cited by this paper
• Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension.

  2008cited by this paper
• Genetic Association Studies

  2008cited by this paper
• Endothelin receptor antagonists in pulmonary arterial hypertension

  2008cited by this paper
• Molecular pathogenesis of pulmonary arterial hypertension.

  2008cited by this paper
• BMC Pulmonary Medicine BioMed Central Review From arginine methylation to ADMA: A novel mechanism with therapeutic potential in chronic lung diseases

  2008cited by this paper
• Vascular endothelial growth factor of the lung: friend or foe.

  2008cited by this paper
• Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension.

  2006cited by this paper
• [Serotonin and pulmonary arterial hypertension].

  2006cited by this paper
• Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia.

  2006influential reference
• Genetic association of the serotonin transporter in pulmonary arterial hypertension.

  2006cited by this paper
• Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension

  2006cited by this paper
• Sérotonine et hypertension artérielle pulmonaire

  2006cited by this paper
• Endothelin receptor antagonists for pulmonary arterial hypertension.

  2005influential reference
• Organization of the human serotonin transporter gene

  2005cited by this paper
• Serotonin Transporter Inhibition Prevents and Reverses Monocrotaline-Induced Pulmonary Hypertension in Rats

  2005cited by this paper
• Smooth muscle cell matrix metalloproteinases in idiopathic pulmonary arterial hypertension

  2005cited by this paper
• Proliferation and signaling in fibroblasts: role of 5-hydroxytryptamine2A receptor and transporter.

  2004cited by this paper
• Overexpression of the 5-Hydroxytryptamine Transporter Gene: Effect on Pulmonary Hemodynamics and Hypoxia-Induced Pulmonary Hypertension

  2004cited by this paper
• Serotonin-Induced Smooth Muscle Hyperplasia in Various Forms of Human Pulmonary Hypertension

  2004cited by this paper
• Oxidative stress in severe pulmonary hypertension.

  2004cited by this paper
• Elevated basic fibroblast growth factor levels in patients with pulmonary arterial hypertension.

  2004cited by this paper
• Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension.

  2004cited by this paper
• Measuring inconsistency in meta-analyses

  2003cited by this paper
• PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression.

  2003influential reference
• Peroxisome Proliferator-Activated Receptor Gamma (PPAR&ggr;) Expression Is Decreased in Pulmonary Hypertension and Affects Endothelial Cell Growth

  2003cited by this paper
• Primary pulmonary hypertension.

  2003cited by this paper
• Expression of human herpesvirus 8 in primary pulmonary hypertension.

  2003cited by this paper
• Expression of angiogenesis‐related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis

  2001cited by this paper
• Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension.

  2001cited by this paper
• 5‐hydroxytryptamine and the pulmonary circulation: receptors, transporters and relevance to pulmonary arterial hypertension

  2000cited by this paper
• Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene.

  2000cited by this paper
• Elastase and the pathobiology of unexplained pulmonary hypertension.

  1998cited by this paper
• Attenuated K+ channel gene transcription in primary pulmonary hypertension.

  1998cited by this paper
• Primary pulmonary hypertension.

  1997cited by this paper
• Quantitative Synthesis in Systematic Reviews

  1997cited by this paper
• Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

  1996cited by this paper
• Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension.

  1995cited by this paper
• Expression of endothelin-1 in the lungs of patients with pulmonary hypertension.

  1993cited by this paper
• An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.

  1992cited by this paper
• Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

  1990cited by this paper
• Primary Pulmonary Hypertension

  1988cited by this paper
• Primary pulmonary hypertension.

  1987cited by this paper

• Identification of Hub Genes and MicroRNAs Associated With Idiopathic Pulmonary Arterial Hypertension by Integrated Bioinformatics Analyses

  2021cites this paper
• Bone morphogenetic protein 9, and its genetic variants contribute to susceptibility of idiopathic pulmonary arterial hypertension

  2020cites this paper
• Increased pulmonary serotonin transporter in patients with chronic obstructive pulmonary disease who developed pulmonary hypertension

  2020cites this paper
• Analysis of Angiotensin Converting Enzyme, Endothelial Nitric Oxide Synthase & Serotonin Gene Polymorphisms among Atrial Septal Defect Subjects with and without Pulmonary Arterial Hypertension

  2018cites this paper
• The Role of Serotonin Transporter in Human Lung Development and in Neonatal Lung Disorders

  2017cites this paper
• Pulmonary , gastrointestinal and urogenital pharmacology RP 5063 , a novel , multimodal , serotonin receptor modulator , prevents monocrotaline-induced pulmonary arterial hypertension in rats

  2017cites this paper
• Metabolic Functions of the Lung, Disorders and Associated Pathologies

  2016cites this paper
• Review of the Ongoing Story of Appetite Suppressants, Serotonin Pathway, and Pulmonary Vascular Disease.

  2016cites this paper
• Translationally Controlled Tumour Protein as a Novel Therapeutic Target in Pulmonary Arterial Hypertension

  2016cites this paper
• Association between eNOS 4 b / a polymorphism and susceptibility of pulmonary hypertension : a meta-analysis of 6 studies

  2016cites this paper
• Molecular Biological Aspects, Therapeutic Targets and New Treatment Strategies

  2015cites this paper
• Sublingual microcirculation in pulmonary arterial hypertension.

  2014cites this paper
• The 5-HTTLPR genotype modulates heart rate variability and its adjustment by pharmacological panic challenge in healthy men.

  2014cites this paper
• General and specific effects of early-life psychosocial adversities on adolescent grey matter volume

  2014cites this paper