Here we propose a mechanism of cell targeting and translocation for an S-type pyocin, pyocin SD2. Understanding and exploiting the mechanisms by which pyocins target, penetrate and kill Pseudomonas aeruginosa is a promising approach to antibiotic development.
Discovery, characterization and in vivo activity of pyocin SD2, a protein antibiotic from Pseudomonas aeruginosa
Laura C. McCaughey,I. Josts,R. Grinter,P. White,O. Byron,N. Tucker,J. Matthews,C. Kleanthous,C. Whitchurch,D. Walker
Published 2016 in Biochemical Journal
ABSTRACT
PUBLICATION RECORD
- Publication year
2016
- Venue
Biochemical Journal
- Publication date
2016-06-01
- Fields of study
Biology, Medicine, Chemistry
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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