Runt‐related transcription factor 3 is associated with ulcerative colitis and shows epistasis with solute carrier family 22, members 4 and 5

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Inflammatory Bowel Diseases

• Publication date

  2008-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/ibd.20610PMID 18668679
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• ATG16L1 and IL23R Are Associated With Inflammatory Bowel Diseases but Not With Celiac Disease in The Netherlands

  2008influential reference
• Decreased P‐glycoprotein (P‐gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels

  2007cited by this paper
• Unravelling the pathogenesis of inflammatory bowel disease

  2007cited by this paper
• Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease

  2007cited by this paper
• CARD15 in inflammatory bowel disease and Crohn's disease phenotypes: an association study and pooled analysis.

  2006cited by this paper
• Tumor suppressor gene Runx3 sensitizes gastric cancer cells to chemotherapeutic drugs by downregulating Bcl‐2, MDR‐1 and MRP‐1

  2005influential reference
• Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn’s disease

  2005cited by this paper
• 1'-acetoxychavicol acetate is a novel nuclear factor kappaB inhibitor with significant activity against multiple myeloma in vitro and in vivo.

  2005cited by this paper
• Association Between Toll‐like Receptor 4 and Inflammatory Bowel Disease

  2005cited by this paper
• RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization.

  2005cited by this paper
• Functional variants of OCTN cation transporter genes are associated with Crohn disease

  2004cited by this paper
• Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia.

  2004cited by this paper
• Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus

  2004cited by this paper
• An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

  2003influential reference
• Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics.

  2003cited by this paper
• The HLA class III subregion is responsible for an increased breast cancer risk.

  2003cited by this paper
• Cancer: New-age tumour suppressors

  2002cited by this paper
• Transforming growth factor-beta in T-cell biology.

  2002cited by this paper
• Inflammatory bowel disease.

  2002cited by this paper
• Causal relationship between the loss of RUNX3 expression and gastric cancer.

  2002cited by this paper
• Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

  2001cited by this paper
• Primer3 on the WWW for general users and for biologist programmers.

  2000cited by this paper
• A Simple Classification of Crohn's Disease: Report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998

  2000cited by this paper
• Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration.

  2000cited by this paper
• Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1.

  1998cited by this paper
• Identification and Characterization of a Conserved Erythroid-specific Enhancer Located in Intron 8 of the Human 5-Aminolevulinate Synthase 2 Gene*

  1998cited by this paper
• Mapping of a susceptibility locus for Crohn's disease on chromosome 16

  1996cited by this paper
• AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization.

  1994cited by this paper
• Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

  1993cited by this paper
• Familial occurrence of inflammatory bowel disease.

  1991cited by this paper
• The role of adenylate cyclase in the D-2 modulation of the release of dopamine: a microdialysis study in the striatum of the rat M. Santiago and B.H.C. Westerink. Centre for Pharmacy, University of Groningen, Groningen, The Netherlands

  1989cited by this paper
• Incidence and prevalence of ulcerative colitis and Crohn's disease in the County of Copenhagen, 1962 to 1978.

  1982cited by this paper

• An Upstream RUNX3 Enhancer, eR3 (−18m/−28h), Regulates the Development of Gut‐Associated Anti‐Tumorigenic CD8+CD103+ Cytotoxic T Lymphocytes in Mouse and Human

  2025cites this paper
• N-ethyl-N-nitrosourea (ENU)-induced C-terminal truncation of Runx3 results in autoimmune colitis associated with Th17/Treg imbalance.

  2024cites this paper
• Inflammation and Organic Cation Transporters Novel (OCTNs)

  2024cites this paper
• Methylation of RUNX3 Promoter 2 in the Whole Blood of Children with Ulcerative Colitis

  2022cites this paper
• Enhanced neoplasia detection in chronic ulcerative colitis: the ENDCaP-C diagnostic accuracy study

  2021cites this paper
• RUNX3 is up-regulated in abdominal aortic aneurysm and regulates the function of vascular smooth muscle cells by regulating TGF-β1

  2021cites this paper
• A dual role for DNA binding by Runt in activation and repression of sloppy paired transcription

  2021cites this paper
• Waiting in the wings: RUNX3 reveals hidden depths of immune regulation with potential implications for inflammatory bowel disease

  2021cites this paper
• Transcription Factors That Regulate the Pathogenesis of Ulcerative Colitis

  2020cites this paper
• Loss of RUNX3 Immunoreactivity in Non-Neoplastic Rectal Mucosa May Predict the Occurrence of Ulcerative Colitis-Associated Colorectal Cancer

  2019cites this paper
• Viewpoint: Toward the Genetic Architecture of Disease Severity in Inflammatory Bowel Diseases.

  2018cites this paper
• Difference in Pathomechanism Between Crohn's Disease and Ulcerative Colitis Revealed by Colon Transcriptome.

  2018cites this paper
• ERAP1/ERAP2 and RUNX3 polymorphisms are not associated with ankylosing spondylitis susceptibility in Chinese Han

  2018cites this paper
• Validation of epigenetic markers to identify colitis associated cancer: Results of module 1 of the ENDCAP-C study

  2018cites this paper
• Epigenetics of paediatric Crohn's disease

  2017influential citation
• Runx3 in Immunity, Inflammation and Cancer.

  2017cites this paper
• Co-Occurrence of Platelet Dysfunction , Myeloid Malignancy and IgA Deficiency in a Family with a Novel RUNX 1 Mutation

  2017cites this paper
• Genetically engineered mouse models for studying inflammatory bowel disease

  2016cites this paper
• Runx3 specifies lineage commitment of innate lymphoid cells

  2015cites this paper
• The RUNX complex: reaching beyond haematopoiesis into immunity

  2015cites this paper
• Runx3 at the interface of immunity, inflammation and cancer.

  2015cites this paper
• Targeting Pim1 kinase in the treatment of peanut allergy

  2014cites this paper
• The False Paradigm of RUNX3 Function as Tumor Suppressor in Gastric Cancer

  2013cites this paper
• Thiopurine treatment in patients with Crohn's disease leads to a selective reduction of an effector cytotoxic gene expression signature revealed by whole-genome expression profiling.

  2013cites this paper
• Are spondylarthritides related but distinct conditions or a single disease with a heterogeneous phenotype?

  2013cites this paper
• Single-nucleotide polymorphisms in inflammatory bowel disease.

  2012cites this paper
• Association between OCTN1/2 gene polymorphisms (1672C-T, 207G-C) and susceptibility of Crohn's disease: a meta-analysis

  2011cites this paper
• Haplotype in the IBD5 region is associated with refractory Crohn’s disease in Slovenian patients and modulates expression of the SLC22A5 gene

  2011cites this paper
• Colonic expression of Runx 3 protein and TGF-毬 1 and their correlation in patients with irritable bowel syndrome

  2011cites this paper
• Colonic expression of Runx3 protein and TGF-β(1) and their correlation in patients with irritable bowel syndrome.

  2011cites this paper
• Association of caspase-9 and RUNX3 with inflammatory bowel disease.

  2011cites this paper
• RUNX3 copy number predicts the development of UC-associated colorectal cancer.

  2010cites this paper
• RUNX 3 copy number predicts the development of UC-associated colorectal cancer

  2010cites this paper
• Chromatin immunoprecipitation and association study revealed a possible role of Runt-related transcription factor 3 in the ulcerative colitis of Chinese population.

  2010cites this paper
• Genetic variants in the Runt‐related transcription factor 3 gene contribute to gastric cancer risk in a Chinese population

  2009cites this paper
• Runx3-deficient mouse strains circa 2008: resemblance and dissimilarity.

  2009cites this paper
• Abdulahad, W. H., Stegeman, C. A., Limburg, P. C., Kallenberg, C. G. A. Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission. ARTHRITIS AND RHEUMATISM 58(7): 2196-2205, 2008 UMCG Disciplinegroep: PAT-LAB IGK REUMA NEFRO

  2008cites this paper
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  2007cites this paper