Resistance Exercise’s Ability to Reverse Cancer-Induced Anabolic Resistance

Ryan N. Montalvo,J. Hardee,Brandon N. VanderVeen,J. Carson

Published 2018 in Exercise and sport sciences reviews

ABSTRACT

Skeletal muscle has the dynamic capability to modulate protein turnover in response to anabolic stimuli, such as feeding and contraction. We propose that anabolic resistance, the suppressed ability to induce protein synthesis, is central to cancer-induced muscle wasting. Furthermore, we propose that resistance exercise training has the potential to attenuate or treat cancer-induced anabolic resistance through improvements in oxidative metabolism.

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