Antidepressant-like effects of a cocoa polyphenolic extract in Wistar–Unilever rats

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Nutritional neuroscience

• Publication date

  2008-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1179/147683008X344165PMID 19000380
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Adenosine deaminase, nitric oxide, superoxide dismutase, and xanthine oxidase in patients with major depression: impact of antidepressant treatment.

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• Antidepressant-like effect of Cecropia glazioui Sneth and its constituents - in vivo and in vitro characterization of the underlying mechanism.

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• Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans.

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• Preventive antioxidant effects of cocoa polyphenolic extract on free radical production and cognitive performances after heat exposure in Wistar rats.

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• The changes of oxidative stress and human 8-hydroxyguanine glycosylase1 gene expression in depressive patients with acute leukemia.

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• Role of alpha2 receptors in quercetin-induced behavioral despair in mice.

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• Effects of low habitual cocoa intake on blood pressure and bioactive nitric oxide: a randomized controlled trial.

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• Antidepressant-like effect of hyperfoliatin, a polyisoprenylated phloroglucinol derivative from Hypericum perfoliatum (Clusiaceae) is associated with an inhibition of neuronal monoamines uptake.

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• Antidepressant and antistress activity of GC‐MS characterized lipophilic extracts of Ginkgo biloba leaves

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• The hydroalcoholic extract of Salvia elegans induces anxiolytic- and antidepressant-like effects in rats.

  2006cited by this paper
• Acute and chronic effects of flavanol-rich cocoa on vascular function in subjects with coronary artery disease: a randomized double-blind placebo-controlled study.

  2006influential reference
• Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: Impact of past episodes

  2006cited by this paper
• Antidepressant effect of extracts from Ginkgo biloba leaves in behavioral models.

  2006cited by this paper
• Rapid recovery from major depression using magnesium treatment.

  2006cited by this paper
• Selective Serotonin-Reuptake Inhibitors and Risk of Persistent Pulmonary Hypertension of the Newborn

  2006cited by this paper
• Oxidative stress in blood platelets from schizophrenic patients

  2005cited by this paper
• Ingested cocoa can prevent high-fat diet-induced obesity by regulating the expression of genes for fatty acid metabolism.

  2005cited by this paper
• Anxiolytic and antidepressant-like effects of the hydroalcoholic extract from Aloysia polystachya in rats.

  2005cited by this paper
• The effect of Malaysian cocoa extract on glucose levels and lipid profiles in diabetic rats.

  2005cited by this paper
• Polyphenols: antioxidants and beyond.

  2005cited by this paper
• Cell Signaling Pathways in the Neuroprotective Actions of the Green Tea Polyphenol (-)-epigallocatechin-3-gallate: Implications for Neurodegenerative Diseases

  2005cited by this paper
• Pentameric procyanidin from Theobroma cacao selectively inhibits growth of human breast cancer cells

  2005cited by this paper
• Antidepressant-like effect of icariin and its possible mechanism in mice.

  2005cited by this paper
• Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment

  2005cited by this paper
• Effects of Green Tea Polyphenol on Cognitive and Acetylcholinesterase Activities

  2004cited by this paper
• Polyphenols: food sources and bioavailability.

  2004cited by this paper
• Endocannabinoids accumulate in spinal cord of SOD1G93A transgenic mice

  2004cited by this paper
• Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (‐)‐epigallocatechin‐3‐gallate: implications for neurodegenerative diseases

  2004cited by this paper
• Antidepressant- and anxiolytic-like activity of magnesium in mice.

  2004cited by this paper
• Antioxidant enzyme activities and oxidative stress in affective disorders

  2004cited by this paper
• The vasculoprotective effects of flavonoid-rich cocoa and chocolate

  2004cited by this paper
• Vascular effects of cocoa rich in flavan-3-ols.

  2003cited by this paper
• Potential Therapeutic Properties of Green Tea Polyphenols in Parkinson’s Disease

  2003cited by this paper
• Antidepressant-induced hepatotoxicity.

  2003cited by this paper
• Antidepressant Activity of Quercetin, a Bioflavonoid, in Streptozotocin-Induced Diabetic Mice

  2003cited by this paper
• Is the Arginine-Nitric Oxide Pathway Involved in the Pathogenesis of Schizophrenia?

  2003cited by this paper
• Antidepressant-induced hepatotoxicity

  2002cited by this paper
• Possible Role of Nitric Oxide and Adrenomedullin in Bipolar Affective Disorder

  2002cited by this paper
• Cocoa flavanols and cardiovascular health

  2002cited by this paper
• Polyphenols: do they play a role in the prevention of human pathologies?

  2002cited by this paper
• Body weight changes associated with psychopharmacology.

  2002cited by this paper
• Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa.

  2002cited by this paper
• Antidepressant medications: a review of the evidence for drug-induced sexual dysfunction.

  2002cited by this paper
• Inhibitory Effects of Cocoa Flavanols and Procyanidin Oligomers on Free Radical-Induced Erythrocyte Hemolysis

  2002cited by this paper
• Antidepressant effects of apocynum venetum leaves in a forced swimming test.

  2001cited by this paper
• Pharmacological and Endocrine Effects of Hypericum Perforatum and Hypericin After Repeated Treatment

  2001cited by this paper
• More antioxidants in cocoa.

  2001cited by this paper
• A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review

  2001cited by this paper
• Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments.

  2001cited by this paper
• Major depressive disorder.

  2000cited by this paper
• Flavonoids from Hypericum perforatum show antidepressant activity in the forced swimming test.

  2000cited by this paper
• A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage.

  2000cited by this paper
• Phenolic antioxidants attenuate neuronal cell death following uptake of oxidized low-density lipoprotein.

  2000cited by this paper
• Cocoa inhibits platelet activation and function.

  2000cited by this paper
• Procyanidin content and variation in some commonly consumed foods.

  2000cited by this paper
• HPLC method for the quantification of procyanidins in cocoa and chocolate samples and correlation to total antioxidant capacity.

  1999cited by this paper
• Protection against peroxynitrite by cocoa polyphenol oligomers

  1999cited by this paper
• Identification of procyanidins in cocoa (Theobroma cacao) and chocolate using high-performance liquid chromatography/mass spectrometry.

  1999cited by this paper
• Antioxidative Polyphenols Isolated from Theobroma cacao.

  1998cited by this paper
• Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study.

  1997cited by this paper
• Vegetables, fruit, and cancer prevention: a review.

  1996cited by this paper
• Dietary Flavonoids, Antioxidant Vitamins, and Incidence of Stroke: The Zutphen Study

  1996cited by this paper
• Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study.

  1996cited by this paper
• Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study.

  1995cited by this paper
• Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study.

  1993cited by this paper
• Depression as a Consequence of Inadequate Neurochemical Adaptation in Response to Stressors

  1992influential reference
• Effects of combined administration of diazepam and imipramine hydrochloride in rats.

  1986cited by this paper
• Free radicals in biology and medicine

  1985cited by this paper
• Antidepressants: Neurochemical, Behavioral, and Clinical Perspectives

  1982cited by this paper
• Depression: The predisposing influence of stress

  1982cited by this paper
• Behavioural despair in rats: a new model sensitive to antidepressant treatments.

  1978cited by this paper
• Depression: a new animal model sensitive to antidepressant treatments

  1977cited by this paper
• Cocoa inhibits platelet activation and function 1 , 2

  year unknowncited by this paper
• Role of (cid:2) 2 Receptors in Quercetin-Induced Behavioral Despair in Mice

  year unknowncited by this paper

• Diet enriched with high-phenolic cocoa potentiates hippocampal brain-derived neurotrophic factor expression and neurogenesis in healthy adult micewith subtle effects on memory.

  2024cites this paper
• Zebrafish: A Model Deciphering the Impact of Flavonoids on Neurodegenerative Disorders

  2023influential citation
• Antidepressant-like active ingredients and their related mechanisms of functional foods or medicine and food homologous products

  2023cites this paper
• Cocoa Flavanols and the Aging Brain.

  2022cites this paper
• Cyrcadian Rhythm, Mood, and Temporal Patterns of Eating Chocolate: A Scoping Review of Physiology, Findings, and Future Directions

  2022cites this paper
• Natural Phytochemicals for the Treatment of Major Depressive Disorder: A Mini-Review of Pre- and Clinical Studies.

  2022cites this paper
• Natural Products for the Treatment of Post-stroke Depression

  2022cites this paper
• Medicinal Plants in the Treatment of Depression: Evidence from Preclinical Studies

  2021cites this paper
• Chemical and biological properties of cocoa beans affected by processing: a review

  2021cites this paper
• Serotonergic and noradrenergic response of ethanol extract; opioidergic response of ethyl acetate extract of Dicranopteris linearis L. leaf

  2021cites this paper
• Attitudes Toward Psychological Disorders and Alternative Medicine in Saudi Participants

  2021cites this paper
• Behavioral, Biochemical and Histopathological effects of Standardised Pomegranate extract with Vinpocetine, Propolis or Cocoa in a rat model of Parkinson’s disease

  2020cites this paper
• CREB and BDNF: Neurobiology and treatment of Alzheimer's disease.

  2020cites this paper
• Gut Microbiota: A Pivotal Hub for Polyphenols as Antidepressants.

  2020cites this paper
• (–)-Epicatechin Reduces the Blood Pressure of Young Borderline Hypertensive Rats During the Post-Treatment Period

  2020cites this paper
• Herbal Beverages and Brain Function in Health and Disease

  2019cites this paper
• Phytochemical Analysis and Antidepressant Activity of Ixora coccinea Extracts in Experimental Models of Depression in Mice

  2018cites this paper
• Cocoa beans improve mitochondrial biogenesis via PPARγ/PGC1α dependent signalling pathway in MPP+ intoxicated human neuroblastoma cells (SH-SY5Y)†

  2018cites this paper
• Phytochemistry and pharmacology of anti-depressant medicinal plants: A review.

  2018cites this paper
• A comparative study of dietary habits and nutritional intakes among Korean adults according to current depression status

  2018cites this paper
• Effects of Resveratrol and Other Polyphenols on the Most Common Brain Age-Related Diseases.

  2017cites this paper
• Chocolate and Depressive Symptoms in a Cross-sectional Analysis

  2017cites this paper
• Influència d’una dieta rica en cacau sobre el sistema immunitari intestinal de rates sensibilitzades

  2017cites this paper
• Natural products, micronutrients, and nutraceuticals for the treatment of depression: A short review

  2017cites this paper
• Evaluation of the antidepressant- and anxiolytic-like effects of a hydrophilic extract from the green seaweed Ulva sp. in rats

  2017cites this paper
• Cocoa and Human Health: From Head to Foot—A Review

  2016cites this paper
• Nepeta menthoides Boiss. & Buhse freeze-dried aqueous extract versus sertraline in the treatment of major depression: A double blind randomized controlled trial.

  2016cites this paper
• (−)-Epicatechin Prevents Blood Pressure Increase and Reduces Locomotor Hyperactivity in Young Spontaneously Hypertensive Rats

  2016cites this paper
• Antidepressant-like effects and mechanisms of flavonoids and related analogues.

  2016cites this paper
• CITRULLUS COLOCYNTHIS FRUIT EXTRACT AS AN ANTI-DEPRESSANT IN MICE

  2016cites this paper
• Phytochemical screening and evaluation of biological activities of Acacia hydaspica (R. Parker).

  2015influential citation
• Polyphenols and depression: from chemistry to medicine.

  2015cites this paper
• Oxidative stress and post-stroke depression: possible therapeutic role of polyphenols?

  2015cites this paper
• NRF2 COMO POTENCIAL ALVO FARMACOLÓGICO NO TRATAMENTO DA DEPRESSÃO E DA DOR NEUROPÁTICA ASSOCIADAS AO DIABETES

  2015cites this paper
• Plant-derived flavanol (−)epicatechin mitigates anxiety in association with elevated hippocampal monoamine and BDNF levels, but does not influence pattern separation in mice

  2015cites this paper
• Psychiatric Disorders and Polyphenols: Can They Be Helpful in Therapy?

  2015cites this paper
• An Increase in Plasma Homovanillic Acid with Cocoa Extract Consumption Is Associated with the Alleviation of Depressive Symptoms in Overweight or Obese Adults on an Energy Restricted Diet in a Randomized Controlled Trial.

  2015cites this paper
• The flavonol epicatechin reverses the suppressive effects of a stressor on long-term memory formation

  2014cites this paper
• Ficus religiosa L. figs--a potential herbal adjuvant to phenytoin for improved management of epilepsy and associated behavioral comorbidities.

  2014cites this paper
• PHYTOFLAVONOIDS: ANTIEPILEPTICS FOR THE FUTURE

  2014cites this paper
• Antidepressant and Anxiolytic Effects of the Methanol Root Extract of Capparis thonningii: Involvement of Monoaminergic, Cholinergic and GABAergic Systems

  2014cites this paper
• Cocoa and Chocolate: Chemistry, Biochemistry, and Beneficial Brain Effects

  2013cites this paper
• The neuroprotective effects of cocoa flavanol and its influence on cognitive performance.

  2013cites this paper
• Enhanced cognitive function and antidepressant-like effects after krill oil supplementation in rats

  2013cites this paper
• Nutritional strategies for dealing with depression.

  2013cites this paper
• Benefits of flavanol-rich cocoa-derived products for mental well-being: A review

  2013cites this paper
• Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology

  2012influential citation
• The Role of Dietary Polyphenols on Adult Hippocampal Neurogenesis: Molecular Mechanisms and Behavioural Effects on Depression and Anxiety

  2012cites this paper
• Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2013

  2012influential citation
• Evidence for the involvement of the monoaminergic system, but not the opioid system in the antidepressant-like activity of ellagic acid in mice.

  2012cites this paper
• Mood food: chocolate and depressive symptoms in a cross-sectional analysis.

  2010cites this paper
• Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease

  2010cites this paper
• Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice.

  2010cites this paper
• The Effectiveness of Horticultural Therapy Groups on Adults with a Diagnosis of Depression

  2010cites this paper
• Impact of diet on adult hippocampal neurogenesis

  2009cites this paper
• Antidepressant-like properties of cocoa ' s polyphenols The role of flavanoids and flavanols on depression

  2009cites this paper
• Eating chocolate can significantly protect the skin from UV light

  2009cites this paper