Differentiation of Rodent Bone Marrow Mesenchymal Stem Cells into Intervertebral Disc-like Cells Following Coculture with Rat Disc Tissue

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Tissue Engineering. Part A

• Publication date

  2009-06-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/ten.TEA.2008.0458PMID 19191570
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Engineered microenvironments for self-renewal and musculoskeletal differentiation of stem cells.

  2011cited by this paper
• Differentiation of mesenchymal stem cells in heparin-containing hydrogels via coculture with osteoblasts

  2011cited by this paper
• Tissue engineering for intervertebral disk degeneration.

  2011cited by this paper
• Cells and Biomaterials for Intervertebral Disc Regeneration

  2010cited by this paper
• The fate of transplanted xenogeneic bone marrow‐derived stem cells in rat intervertebral discs

  2009cited by this paper
• In vitro migration assays of neural stem cells.

  2008cited by this paper
• Stem Cell Niche: Microenvironment and Beyond*

  2008cited by this paper
• Human mesenchymal stem cell differentiation to NP-like cells in chitosan-glycerophosphate hydrogels.

  2008cited by this paper
• Engineering the Stem Cell Microenvironment

  2007cited by this paper
• Human bone-marrow-derived mesenchymal stem cells: biological characteristics and potential role in therapy of degenerative diseases

  2007cited by this paper
• The In Vitro Migration Capacity of Human Bone Marrow Mesenchymal Stem Cells: Comparison of Chemokine and Growth Factor Chemotactic Activities

  2007cited by this paper
• Adult mesenchymal stem cells for tissue engineering versus regenerative medicine

  2007cited by this paper
• Comparison of cellular response in bovine intervertebral disc cells and articular chondrocytes: effects .of lipopolysaccharide on proteoglycan metabolism

  2006cited by this paper
• Notochordal Cell Produce and Assemble Extracellular Matrix in a Distinct Manner, Which May Be Responsible for the Maintenance of Healthy Nucleus Pulposus

  2006cited by this paper
• Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc.

  2006cited by this paper
• Intervertebral Disc Cell–Mediated Mesenchymal Stem Cell Differentiation

  2006cited by this paper
• The control of chondrogenesis

  2006cited by this paper
• Interaction of Human Mesenchymal Stem Cells With Disc Cells: Changes in Extracellular Matrix Biosynthesis

  2006cited by this paper
• Stem Cells and Their Niches

  2006cited by this paper
• The differentiation of bone marrow mesenchymal stem cells into chondrocyte-like cells on poly-L-lactic acid (PLLA) scaffolds.

  2006influential reference
• cytokineshuman mesenchymal stem cells: differential regulation by inflammatory MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of

  2006cited by this paper
• Human mesenchymal stem cells modulate allogeneic immune cell responses.

  2005cited by this paper
• Bone Mesenchymal Stem Cells Transplanted into Rabbit Intervertebral Discs Can Increase Proteoglycans

  2005cited by this paper
• Induction of Intervertebral Disc–Like Cells From Adult Mesenchymal Stem Cells

  2005cited by this paper
• Cytokine profiles in conditioned media from cultured human intervertebral disc tissue. Implications of their effect on bone marrow stem cell metabolism.

  2005cited by this paper
• SURVIVAL AND DIFFERENTIATION OF SYNERGENEIC BONE MARROW-DERIVED MONONUCLEAR CELLS IN RAT INTERVERTEBRAL DISCS.

  2005cited by this paper
• Cytokine profiles in conditioned media from cultured human intervertebral disc tissue

  2005cited by this paper
• Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.

  2005cited by this paper
• Cell therapy for disc degeneration--potentials and pitfalls.

  2004cited by this paper
• Upregulation of the Viability of Nucleus Pulposus Cells by Bone Marrow-Derived Stromal Cells: Significance of Direct Cell-to-Cell Contact in Coculture System

  2004cited by this paper
• Differentiation of Mesenchymal Stem Cells Towards a Nucleus Pulposus-like Phenotype In Vitro: Implications for Cell-Based Transplantation Therapy

  2004cited by this paper
• Cell fusion and reprogramming: resolving our transdifferences.

  2004cited by this paper
• Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow

  2004cited by this paper
• Intervertebral Disc Cell Therapy for Regeneration: Mesenchymal Stem Cell Implantation in Rat Intervertebral Discs

  2004cited by this paper
• Human intervertebral disc cell morphology and cytoskeletal composition: a preliminary study of regional variations in health and disease

  2003cited by this paper
• Transplanted bone marrow regenerates liver by cell fusion

  2003cited by this paper
• Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration.

  2003cited by this paper
• The molecular basis of intervertebral disk degeneration.

  2003cited by this paper
• The Notochordal Cell in the Nucleus Pulposus: A Review in the Context of Tissue Engineering

  2003cited by this paper
• Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

  2002cited by this paper
• Regional variations in the cellular matrix of the annulus fibrosus of the intervertebral disc

  2002cited by this paper
• Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion

  2002cited by this paper
• Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo.

  2002cited by this paper
• Changing potency by spontaneous fusion

  2002cited by this paper
• Polycythemia vera: myths, mechanisms, and management.

  2002cited by this paper
• L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway.

  2001cited by this paper
• Phosphorylation of SOX9 by Cyclic AMP-Dependent Protein Kinase A Enhances SOX9's Ability To Transactivate aCol2a1 Chondrocyte-Specific Enhancer

  2000cited by this paper
• Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model.

  2000cited by this paper
• Multilineage potential of adult human mesenchymal stem cells.

  1999cited by this paper
• Sox9 is required for cartilage formation

  1999cited by this paper
• Characterisation of cytoplasm‐filled processes in cells of the intervertebral disc

  1998cited by this paper
• Immortalization of human marrow stromal cells by retroviral transduction with a temperature sensitive oncogene: identification of bipotential precursor cells capable of directed differentiation to either an osteoblast or adipocyte phenotype.

  1998cited by this paper
• SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

  1997cited by this paper
• Quantification of 35S-labeled proteoglycans complexed to alcian blue by rapid filtration in multiwell plates.

  1994cited by this paper
• A microassay to quantitate collagen synthesis by cells in culture.

  1990cited by this paper
• Secretory cells in the nucleus pulposus of the adult human intervertebral disc. A preliminary report.

  1986cited by this paper
• Fluorometric quantification of DNA in cells and tissue.

  1983cited by this paper
• Cell Therapy for Age ! Related Intervertebral Disc Pathologies

  year unknowncited by this paper

• An injectable anti-vascularization functionalized hydrogel for degenerative nucleus pulposus repair

  2024cites this paper
• A Review: Methodologies to Promote the Differentiation of Mesenchymal Stem Cells for the Regeneration of Intervertebral Disc Cells Following Intervertebral Disc Degeneration

  2023cites this paper
• Intervertebral disc decellularisation: progress and challenges.

  2021cites this paper
• Stem cell therapy in discogenic back pain.

  2019cites this paper
• Therapeutic effects of cell therapy with neonatal human dermal fibroblasts and rabbit dermal fibroblasts on disc degeneration and inflammation.

  2019cites this paper
• Hypoxic Preconditioning Enhances Bone Marrow–Derived Mesenchymal Stem Cell Survival in a Low Oxygen and Nutrient-Limited 3D Microenvironment

  2019cites this paper
• The development of an in vitro culture system for the expansion of notochordal cell populations with retention of phenotype

  2019cites this paper
• SOD3 overexpression alleviates cerebral ischemia‐reperfusion injury in rats

  2019cites this paper
• Aberrantly expressed messenger RNAs and long noncoding RNAs in degenerative nucleus pulposus cells co-cultured with adipose-derived mesenchymal stem cells

  2018cites this paper
• An Analysis of New Approaches and Drug Formulations for Treatment of Chronic Low Back Pain.

  2017cites this paper
• Coculture with Partial Digestion Notochordal Cell-Rich Nucleus Pulposus Tissue Activates Degenerative Human Nucleus Pulposus Cells

  2017influential citation
• Effects of cell type and configuration on anabolic and catabolic activity in 3D co‐culture of mesenchymal stem cells and nucleus pulposus cells

  2016cites this paper
• BMP7-Based Functionalized Self-Assembling Peptides Protect Nucleus Pulposus-Derived Stem Cells From Apoptosis In Vitro

  2016cites this paper
• Establishment of a Cytocompatible Cell-Free Intervertebral Disc Matrix for Chondrogenesis with Human Bone Marrow-Derived Mesenchymal Stromal Cells

  2016cites this paper
• Use of FGF-2 and FGF-18 to direct bone marrow stromal stem cells to chondrogenic and osteogenic lineages

  2016cites this paper
• The In Vitro and In Vivo Osteogenic Capability of the Extraction Socket-Derived Early Healing Tissue.

  2016cites this paper
• Tissue Engineering a Biological Repair Strategy for Lumbar Disc Herniation

  2015cites this paper
• Stimulated Chondrogenesis via Chondrocytes Co-culturing

  2015cites this paper
• Effects of mesenchymal stem cells on interleukin-1β-treated chondrocytes and cartilage in a rat osteoarthritic model

  2015cites this paper
• A Degenerative/Proinflammatory Intervertebral Disc Organ Culture: An Ex Vivo Model for Anti-inflammatory Drug and Cell Therapy

  2015cites this paper
• Stem Cell Approaches to Intervertebral Disc Regeneration: Obstacles from the Disc Microenvironment

  2015cites this paper
• Adipose-derived stem cells improve the viability of nucleus pulposus cells in degenerated intervertebral discs.

  2015cites this paper
• Coculture in Musculoskeletal Tissue Regeneration

  2014cites this paper
• Mesenchymal Stem Cells

  2014cites this paper
• Co‑culture of human nucleus pulposus cells with multipotent mesenchymal stromal cells from human bone marrow reveals formation of tunnelling nanotubes.

  2014cites this paper
• The development of heparin-based materials for tissue engineering applications to treat rotator cuff tendon injuries

  2014cites this paper
• Use of Stem Cells for Regeneration of the Intervertebral Disc

  2014cites this paper
• Stem Cell Therapy for Intervertebral Disk Regeneration

  2014cites this paper
• Can Notochordal Cells Promote Bone Marrow Stromal Cell Potential for Nucleus Pulposus Enrichment? A Simplified In Vitro System

  2014cites this paper
• Using notochordal cells of developmental origin to stimulate nucleus pulposus cells and bone marrow stromal cells for intervertebral disc regeneration

  2014cites this paper
• Co-cultivated mesenchymal stem cells support chondrocytic differentiation of articular chondrocytes

  2013cites this paper
• Title Tissue Engineering for Intervertebral Disk Degeneration

  2013cites this paper
• The effects of microenvironment in mesenchymal stem cell-based regeneration of intervertebral disc.

  2013cites this paper
• Stemming the Degeneration: IVD Stem Cells and Stem Cell Regenerative Therapy for Degenerative Disc Disease.

  2013cites this paper
• The use of stem cells for the treatment of spinal surgical conditions.

  2013cites this paper
• Current and future applications for stem cell therapies in spine surgery.

  2013cites this paper
• Molecular and genetic advances in the regeneration of the intervertebral disc

  2013influential citation
• Chapter 45 – Mesenchymal Stem Cells

  2013cites this paper
• 1 Tissue engineering for intervertebral disc degeneration

  2013cites this paper
• Stem Cell-Mediated Intervertebral Disc Regeneration

  2012influential citation
• Coculture Strategies in Bone Tissue Engineering: The Impact of Culture Conditions on Pluripotent Stem Cell Populations

  2012cites this paper
• Structured Coculture of Mesenchymal Stem Cells and Disc Cells Enhances Differentiation and Proliferation

  2012cites this paper
• Nucleus pulposus replacement and regeneration/repair technologies: present status and future prospects.

  2012cites this paper
• Homing of Mesenchymal Stem Cells in Induced Degenerative Intervertebral Discs in a Whole Organ Culture System

  2012cites this paper
• Structured Bilaminar Coculture Outperforms Stem Cells and Disc Cells in a Simulated Degenerate Disc Environment

  2012cites this paper
• Cell therapy for age-related intervertebral disc pathologies

  2012cites this paper
• Coculture Systems for Mesenchymal Stem Cells

  2012cites this paper
• Design of a Mechanical Loading Device to Culture Intact Bovine Spinal Motion Segments under Multiaxial Motion

  2012cites this paper
• 19 – Nucleus regeneration

  2012cites this paper
• Introduction to biomaterials for spinal surgery

  2012cites this paper
• Differentiation of mesenchymal stem cells in heparin-containing hydrogels via coculture with osteoblasts

  2011cites this paper
• Tissue engineering for intervertebral disk degeneration.

  2011cites this paper
• Chapter 17 – Mesenchymal Stem Cells

  2011cites this paper
• Engineered microenvironments for self-renewal and musculoskeletal differentiation of stem cells.

  2011cites this paper
• CO-CULTURE OF BONE MARROW STROMAL CELLS AND CHONDROCYTES FOR BONE TISSUE ENGINEERING: MICROARRAY STUDY OF CHONDROCYTE SECRETED FACTORS

  2011cites this paper
• Effects of Intervertebral Disc Cells on Neurite Outgrowth From Dorsal Root Ganglion Explants in Culture

  2011cites this paper
• Transplantation of Goat Bone Marrow Stromal Cells to the Degenerating Intervertebral Discin a Goat Disc Injury Model

  2011cites this paper
• Co-culture of chondrocytes and bone marrow mesenchymal stem cells in vitro enhances the expression of cartilaginous extracellular matrix components.

  2011cites this paper
• Développement de l'ingénierie tissulaire du disque intervertébral : de la physiopathologie aux modèles animaux

  2010cites this paper
• Cells and Biomaterials for Intervertebral Disc Regeneration

  2010cites this paper
• Potential applications for using stem cells in spine surgery.

  2010cites this paper
• Human Disk Cells from Degenerated Disks and Mesenchymal Stem Cells in Co-Culture Result in Increased Matrix Production

  2009cites this paper