Neuroblastoma is the most common pediatric extracranial solid tumor. Germline pathogenic variants in ALK and PHOX2B, as well as other cancer predisposition genes, are increasingly implicated in the pathogenesis of neuroblastic tumors. A challenge for clinicians is the identification of children with neuroblastoma who require genetics evaluation for underlying cancer predisposition syndromes (CPS).
Retrospective evaluation of a decision‐support algorithm (MIPOGG) for genetic referrals for children with neuroblastic tumors
Catherine Goudie,N. Cullinan,A. Villani,Natalie Mathews,Kalene van Engelen,D. Malkin,M. Irwin,W. Foulkes
Published 2018 in Pediatric Blood & Cancer
ABSTRACT
PUBLICATION RECORD
- Publication year
2018
- Venue
Pediatric Blood & Cancer
- Publication date
2018-08-16
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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