Factors regulating fat oxidation in human skeletal muscle

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Obesity Reviews

• Publication date

  2011-10-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1111/j.1467-789X.2011.00898.xPMID 21951332
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

  2011cited by this paper
• Beneficial metabolic adaptations due to endurance exercise training in the fasted state.

  2011cited by this paper
• Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

  2010cited by this paper
• Lipid-induced insulin resistance: unravelling the mechanism.

  2010cited by this paper
• Lipid-Induced Insulin Resistance Affects Women Less Than Men and Is Not Accompanied by Inflammation or Impaired Proximal Insulin Signaling

  2010cited by this paper
• Vascular endothelial growth factor B controls endothelial fatty acid uptake

  2010cited by this paper
• Relationship between plasma free fatty acid, intramyocellular triglycerides and long‐chain acylcarnitines in resting humans

  2009cited by this paper
• Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation.

  2009cited by this paper
• Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training.

  2009cited by this paper
• Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness.

  2008cited by this paper
• The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy

  2007cited by this paper
• Muscle metabolism during graded quadriceps exercise in man

  2007cited by this paper
• Fuel metabolism in starvation.

  2006cited by this paper
• Skeletal muscle lipid metabolism in exercise and insulin resistance.

  2006influential reference
• Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase

  2006cited by this paper
• Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise.

  2005influential reference
• Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase

  2004cited by this paper
• Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy.

  2004cited by this paper
• Regulation of plasma long-chain fatty acid oxidation in relation to uptake in human skeletal muscle during exercise.

  2004cited by this paper
• Desnutrin, an Adipocyte Gene Encoding a Novel Patatin Domain-containing Protein, Is Induced by Fasting and Glucocorticoids

  2004cited by this paper
• Regulation of hormone‐sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise

  2004cited by this paper
• Identification, Cloning, Expression, and Purification of Three Novel Human Calcium-independent Phospholipase A2 Family Members Possessing Triacylglycerol Lipase and Acylglycerol Transacylase Activities*

  2004cited by this paper
• Effects of dynamic exercise intensity on the activation of hormone‐sensitive lipase in human skeletal muscle

  2003cited by this paper
• Cloning and expression of the liver and muscle isoforms of ovine carnitine palmitoyltransferase 1: residues within the N-terminus of the muscle isoform influence the kinetic properties of the enzyme.

  2003cited by this paper
• Hormone-sensitive lipase in skeletal muscle: regulatory mechanisms.

  2003cited by this paper
• Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle.

  2003cited by this paper
• Acyl-CoA binding protein is an essential protein in mammalian cell lines.

  2002cited by this paper
• Intramuscular triacylglycerol utilization in human skeletal muscle during exercise: is there a controversy?

  2002cited by this paper
• Gender differences in substrate utilization during submaximal exercise in endurance-trained subjects.

  2002cited by this paper
• The effects of increasing exercise intensity on muscle fuel utilisation in humans

  2001cited by this paper
• Effects of moderate and high glycemic index meals on metabolism and exercise performance.

  2001cited by this paper
• Adrenaline and glycogenolysis in skeletal muscle during exercise: a study in adrenalectomised humans

  2000cited by this paper
• Fatty acid oxidation and the regulation of malonyl-CoA in human muscle.

  2000cited by this paper
• Muscular long-chain fatty acid content during graded exercise in humans.

  1999cited by this paper
• Muscular long-chain fatty acid content during graded exercise in humans.

  1999cited by this paper
• Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo.

  1999cited by this paper
• Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo.

  1999cited by this paper
• Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm.

  1999cited by this paper
• Contraction-induced increase in Vmax of palmitate uptake and oxidation in perfused skeletal muscle.

  1998cited by this paper
• Impact of a fat-rich diet on endurance in man: role of the dietary period.

  1998cited by this paper
• Intracellular Transport of Fatty Acids in Muscle

  1998cited by this paper
• Intracellular transport of fatty acids in muscle. Role of cytoplasmic fatty acid-binding protein.

  1998cited by this paper
• Skeletal muscle malonyl-CoA content at the onset of exercise at varying power outputs in humans.

  1998cited by this paper
• Malonyl CoA as a metabolic switch and a regulator of insulin sensitivity.

  1998cited by this paper
• Muscle enzyme activity in humans: role of substrate availability and training.

  1997cited by this paper
• cDNA Cloning, Tissue Distribution, and Identification of the Catalytic Triad of Monoglyceride Lipase

  1997cited by this paper
• The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis.

  1997influential reference
• Regulation of plasma fatty acid oxidation during low- and high-intensity exercise.

  1997cited by this paper
• Interaction of training and diet on metabolism and endurance during exercise in man.

  1996cited by this paper
• Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein.

  1994cited by this paper
• Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration.

  1993cited by this paper
• Skeletal muscle substrate utilization during submaximal exercise in man: effect of endurance training.

  1993cited by this paper
• Increased plasma FFA uptake and oxidation during prolonged exercise in trained vs. untrained humans.

  1992cited by this paper
• Acetyl group accumulation and pyruvate dehydrogenase activity in human muscle during incremental exercise.

  1991cited by this paper
• Saturation kinetics of palmitate uptake in perfused skeletal muscle

  1991cited by this paper
• Muscle carnitine metabolism during incremental dynamic exercise in humans.

  1990cited by this paper
• Lipoprotein metabolism influenced by training-induced changes in human skeletal muscle.

  1989cited by this paper
• Carnitine and acylcarnitine metabolism during exercise in humans. Dependence on skeletal muscle metabolic state.

  1989cited by this paper
• Isolation and partial characterization of a fatty acid binding protein in rat liver plasma membranes.

  1985cited by this paper
• Carbohydrate feeding during prolonged strenuous exercise can delay fatigue.

  1983cited by this paper
• Influence of blood flow on fatty acid mobilization from lipolytically active adipose tissue

  1981cited by this paper
• The effect of different diets and of insulin on the hormonal response to prolonged exercise.

  1979cited by this paper
• Training induced adaptation of skeletal muscle and metabolism during submaximal exercise

  1977cited by this paper
• Free fatty acid oxidation by forearm muscle at rest, and evidence for an intramuscular lipid pool in the human forearm.

  1976cited by this paper
• Substrate turnover during prolonged exercise in man. Splanchnic and leg metabolism of glucose, free fatty acids, and amino acids.

  1974cited by this paper
• FFA metabolism of normal dogs during steady-state exercise at different work loads.

  1970cited by this paper
• Human forearm muscle metabolism during exercise. II. Uptake, release and oxidation of individual FFA and glycerol.

  1968cited by this paper
• Kinetic analysis of the oxidation of palmitate-1-14C in man during prolonged heavy muscular exercise.

  1967cited by this paper
• The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus.

  1963cited by this paper
• Reversible enzymatic acetylation of carnitine.

  1955cited by this paper
• III. Arbeitsfähigkeit und Ernährung1

  1939cited by this paper
• V. Respiratorischer Quotient und O2‐Aufnahme1

  1939cited by this paper
• The Relative Value of Fat and Carbohydrate as Sources of Muscular Energy: With Appendices on the Correlation between Standard Metabolism and the Respiratory Quotient during Rest and Work.

  1920cited by this paper

• Targeting intramyocellular lipids to improve aging muscle function

  2025cites this paper
• Melatonin induces fiber switching by improvement of mitochondrial oxidative capacity and function via NRF2/RCAN/MEF2 in the vastus lateralis muscle from both sex Zücker diabetic fatty rats.

  2024cites this paper
• Skeletal muscle proteins involved in fatty acid transport influence fatty acid oxidation rates observed during exercise

  2023cites this paper
• State of Knowledge on Molecular Adaptations to Exercise in Humans: Historical Perspectives and Future Directions.

  2022cites this paper
• Exocytosis Proteins: Typical and Atypical Mechanisms of Action in Skeletal Muscle

  2022cites this paper
• Combined effects of a ketogenic diet and exercise training alter mitochondrial and peroxisomal substrate oxidative capacity in skeletal muscle.

  2021cites this paper
• Skeletal muscle energy metabolism in obesity

  2021cites this paper
• Moringa oleifera leaf extract influences oxidative metabolism in C2C12 myotubes through SIRT1-PPARα pathway

  2021cites this paper
• Decreased Blood Glucose and Lactate: Is a Useful Indicator of Recovery Ability in Athletes?

  2020cites this paper
• The Regulation of Adipose Tissue and Skeletal Muscle Substrate Metabolism by Ghrelin

  2020cites this paper
• Lipid metabolic features of skeletal muscle in pathological and physiological conditions

  2020cites this paper
• Unacylated ghrelin stimulates fatty acid oxidation to protect skeletal muscle against palmitate-induced impairment of insulin action in lean but not high-fat fed rats

  2020cites this paper
• Pulses, Global Health, and Sustainability: Future Trends

  2019cites this paper
• Determination and validation of peak fat oxidation in endurance‐trained men using an upper body graded exercise test

  2019cites this paper
• Multi-Target Drugs Against Metabolic Disorders.

  2019cites this paper
• Acute effect of high-intensity interval training on metabolic and inflammatory markers in obese and overweight adolescents: Pilot study

  2019cites this paper
• The effect of diet and exercise on lipid droplet dynamics in human muscle tissue

  2018cites this paper
• The attenuation of metabolic syndrome and improvement of gastrointestinal microarchitecture and physiology by consumption of whole food products in the diet of male wistar rats

  2018cites this paper
• Abdominal and Thigh Muscle Attenuation Is Associated With Visceral Fat and Age in Children and Adolescents With Obesity

  2018influential citation
• Investigation into metabolic profile changes in environmental hypoxia and the potential for dietary nitrate to alleviate hypoxic stress

  2017cites this paper
• Influence of the PDE5 inhibitor tadalafil on redox status and antioxidant defense system in C2C12 skeletal muscle cells

  2017cites this paper
• Sarcopenic obesity or obese sarcopenia: A cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the pathogenesis.

  2017cites this paper
• Metabolism and Whole-Body Fat Oxidation Following Postexercise Carbohydrate or Protein Intake.

  2017cites this paper
• Influence of maximal fat oxidation on long-term weight loss maintenance in humans.

  2017cites this paper
• Can lentil (Lens culinaris Medikus) reduce the risk of obesity

  2017cites this paper
• The in vivo role of AMP-activated protein kinase in the metabolic function of brown and beige adipose tissue

  2016cites this paper
• Genetic Variation of Fatty Acid Oxidation and Obesity, A Literature Review

  2016cites this paper
• Whole-body fat oxidation increases more by prior exercise than overnight fasting in elite endurance athletes.

  2016cites this paper
• Physical activity, body composition, inflammation and effects on antioxidative capacity in sedentary adults

  2016cites this paper
• The effects of active commuting by bike on cardiorespiratory fitness and body composition in healthy, sedentary and overweight adults -A randomized controlled trial

  2016cites this paper
• AN OVERVIEW OF TRAINING METHODS THAT PROMOTE THE HIGHEST LIPID OXIDATION DURING AND AFTER A SINGLE EXERCISE SESSION

  2016influential citation
• Exercise and Regulation of Lipid Metabolism.

  2015cites this paper
• The Effects of Pueraria and Rehmannia Glutinosa Intake and Exercise on Epigenetic Modification in Ovariectomized Rat Skeletal Muscle

  2015cites this paper
• Changes in peak fat oxidation in response to different doses of endurance training

  2015cites this paper
• men: a randomized controlled trial loss on peak fat oxidation in moderately overweight Independent effects of endurance training and weight

  2015cites this paper
• Lipid Profiles of Adipose and Muscle Tissues in Mouse Models of Juvenile Onset of Obesity without High Fat Diet Induction: A Fourier Transform Infrared (FT-IR) Spectroscopic Study

  2015cites this paper
• Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism

  2015cites this paper
• Myotubes from lean and severely obese subjects with and without type 2 diabetes respond differently to an in vitro model of exercise.

  2015cites this paper
• Independent effects of endurance training and weight loss on peak fat oxidation in moderately overweight men: a randomized controlled trial.

  2015cites this paper
• Exercise and diabetes: relevance and causes for response variability

  2015cites this paper
• Prebiotics in obesity.

  2014cites this paper
• Nutrition for the Body: Exploring Nourishment of the body During a 28-day Daniel Fast at Southern Adventist University

  2014cites this paper
• Skeletal muscle energy metabolism in environmental hypoxia: climbing towards consensus

  2014cites this paper
• Lipid homeostasis in exercise.

  2014cites this paper
• The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women.

  2013cites this paper
• Three Dimensional Nutrition: Exploring nourishment of spirit, mind, and body during a 28-day Daniel Fast at Southern Adventist University

  2013influential citation
• Production and release of acylcarnitines by primary myotubes reflect the differences in fasting fat oxidation of the donors.

  2013cites this paper