The role of AQP4 in neuromyelitis optica: More answers, more questions.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Neuroimmunology

• Publication date

  2016-09-15

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.jneuroim.2016.06.002PMID 27609277
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia

  2015influential reference
• Novel hypoglycemic injury mechanism: N‐methyl‐D‐aspartate receptor–mediated white matter damage

  2014cited by this paper
• Longitudinally extensive transverse myelitis with and without aquaporin 4 antibodies.

  2013cited by this paper
• A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

  2012cited by this paper
• Neuromyelitis optica: aquaporin-4 based pathogenesis mechanisms and new therapies.

  2012cited by this paper
• The emerging relationship between neuromyelitis optica and systemic rheumatologic autoimmune disease

  2012cited by this paper
• Aquaporin 4 and neuromyelitis optica.

  2012influential reference
• Neuromyelitis optica IgG and natural killer cells produce NMO lesions in mice without myelin loss

  2012cited by this paper
• Consequences of NMO-IgG binding to aquaporin-4 in neuromyelitis optica

  2012cited by this paper
• Neuromyelitis Optica: An Antibody-Mediated Disorder of the Central Nervous System

  2012cited by this paper
• Aquaporins in clinical medicine.

  2012influential reference
• Potassium channel KIR4.1 as an immune target in multiple sclerosis.

  2012cited by this paper
• Anti–Aquaporin‐4 monoclonal antibody blocker therapy for neuromyelitis optica

  2012cited by this paper
• Idiopathic Transverse Myelitis and Neuromyelitis Optica: Clinical Profiles, Pathophysiology and Therapeutic Choices

  2011influential reference
• Impact of aquaporin‐4 channels on K+ buffering and gap junction coupling in the hippocampus

  2011cited by this paper
• Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes

  2011cited by this paper
• Intravenous Neuromyelitis Optica Autoantibody in Mice Targets Aquaporin-4 in Peripheral Organs and Area Postrema

  2011cited by this paper
• Proinflammatory role of aquaporin‐4 in autoimmune neuroinflammation

  2011cited by this paper
• Evidence against Cellular Internalization in Vivo of NMO-IgG, Aquaporin-4, and Excitatory Amino Acid Transporter 2 in Neuromyelitis Optica*

  2011cited by this paper
• Reappraisal of Aquaporin‐4 Astrocytopathy in Asian Neuromyelitis Optica and Multiple Sclerosis Patients

  2011cited by this paper
• The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction

  2010cited by this paper
• Immunocytochemical Studies of Aquaporin 4, Kir4.1, and α1-syntrophin in the Astrocyte Endfeet of Mouse Brain Capillaries

  2010cited by this paper
• Functional and molecular interactions between aquaporins and Na,K-ATPase.

  2010influential reference
• Inwardly rectifying potassium channels: their structure, function, and physiological roles.

  2010cited by this paper
• Regulation of brain aquaporins.

  2010cited by this paper
• Neuromyelitis optica in France

  2010cited by this paper
• EFNS guidelines on diagnosis and management of neuromyelitis optica

  2010cited by this paper
• Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice.

  2010cited by this paper
• Cell locations for AQP1, AQP4 and 9 in the non-human primate brain.

  2010influential reference
• Water transport between CNS compartments: contributions of aquaporins and cotransporters.

  2010influential reference
• Implication of Kir4.1 Channel in Excess Potassium Clearance: An In Vivo Study on Anesthetized Glial-Conditional Kir4.1 Knock-Out Mice

  2010cited by this paper
• Cytotoxic effect of neuromyelitis optica antibody (NMO-IgG) to astrocytes: an in vitro study.

  2009cited by this paper
• Intrathecal pathogenic anti–aquaporin‐4 antibodies in early neuromyelitis optica

  2009cited by this paper
• Analysis of Astroglial K+ Channel Expression in the Developing Hippocampus Reveals a Predominant Role of the Kir4.1 Subunit

  2009cited by this paper
• Uniquely Hominid Features of Adult Human Astrocytes

  2009cited by this paper
• Real‐time passive volume responses of astrocytes to acute osmotic and ischemic stress in cortical slices and in vivo revealed by two‐photon microscopy

  2009cited by this paper
• Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo

  2009cited by this paper
• Deletion of Astrocyte Connexins 43 and 30 Leads to a Dysmyelinating Phenotype and Hippocampal CA1 Vacuolation

  2009influential reference
• Neuromyelitis optica and non organ-specific autoimmunity.

  2008cited by this paper
• Expression of astrocytic markers aquaporin 4 and connexin 43 is altered in brains of subjects with autism

  2008cited by this paper
• Identification of a molecular target for glutamate regulation of astrocyte water permeability

  2008influential reference
• Differential diagnosis of suspected multiple sclerosis: a consensus approach

  2008cited by this paper
• Aquaporin-4-Deficient Mice Have Increased Extracellular Space without Tortuosity Change

  2008cited by this paper
• Aquaporin-4–binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2

  2008cited by this paper
• Gene expression profiling of astrocytes from hyperammonemic mice reveals altered pathways for water and potassium homeostasis in vivo

  2008cited by this paper
• Excitotoxic Mechanisms of Ischemic Injury in Myelinated White Matter

  2007cited by this paper
• Pathogenic potential of IgG binding to water channel extracellular domain in neuromyelitis optica

  2007cited by this paper
• Glutamate receptors communicate with Na+/K+-ATPase in rat cerebellum granule cells

  2007cited by this paper
• The spectrum of neuromyelitis optica.

  2007cited by this paper
• Aquaporin-4 deficiency down-regulates glutamate uptake and GLT-1 expression in astrocytes.

  2007cited by this paper
• Human astrocytes express aquaporin‐1 and aquaporin‐4 in vitro and in vivo

  2007cited by this paper
• Neuromyelitis optica: changing concepts.

  2007cited by this paper
• Ultrastructural localization of connexins (Cx36, Cx43, Cx45), glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb

  2005cited by this paper
• New possible roles for aquaporin‐4 in astrocytes: cell cytoskeleton and functional relationship with connexin43

  2005cited by this paper
• Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture

  2005cited by this paper
• IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel

  2005cited by this paper
• Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4.1.

  2004influential reference
• A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis.

  2004cited by this paper
• Expression of the AQP-1 water channel in normal human tissues: a semiquantitative study using tissue microarray technology.

  2004cited by this paper
• Regulation of brain aquaporins.

  2004cited by this paper
• Potassium buffering in the central nervous system.

  2004cited by this paper
• Gateways Into Cells Usher in Nobels

  2003cited by this paper
• Multiple sclerosis in the Japanese population.

  2003cited by this paper
• 2003 Nobel Prize. Gateways into cells usher in Nobels.

  2003cited by this paper
• An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain

  2003influential reference
• Intrinsic optical signals in the rat optic nerve: Role for K+ uptake via NKCC1 and swelling of astrocytes

  2002cited by this paper
• Aquaporin-4 expression is increased in oedematous human brain tumours

  2002cited by this paper
• Epidemiological study of multiple sclerosis in Hong Kong Chinese: questionnaire survey.

  2002cited by this paper
• Aquaporins in Brain: Distribution, Physiology, and Pathophysiology

  2002cited by this paper
• MS and neuromyelitis optica in Martinique (French West Indies)

  2001influential reference
• Kir4.1 Potassium Channel Subunit Is Crucial for Oligodendrocyte Development and In Vivo Myelination

  2001cited by this paper
• Aquaporin subtypes in rat cerebral microvessels.

  2001cited by this paper
• Impaired Hearing in Mice Lacking Aquaporin-4 Water Channels*

  2001cited by this paper
• Sodium-potassium-chloride cotransport.

  2000influential reference
• Activity‐dependent extracellular K+ accumulation in rat optic nerve: the role of glial and axonal Na+ pumps

  2000cited by this paper
• Presence of aquaporin-4 and muscarinic receptors in astrocytes and ependymal cells in rat brain: a clue to a common function?

  2000cited by this paper
• Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains

  1999cited by this paper
• Direct immunogold labeling of connexins and aquaporin-4 in freeze-fracture replicas of liver, brain, and spinal cord: factors limiting quantitative analysis

  1999cited by this paper
• HLA-DPB1*0501-associated opticospinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies.

  1999cited by this paper
• The aquaporins. A family of water channel proteins.

  1998cited by this paper
• A retrospective review of patients with clinically definite multiple sclerosis.

  1998cited by this paper
• Aquaporins in the kidney: emerging new aspects.

  1998cited by this paper
• Aquaporins in complex tissues. II. Subcellular distribution in respiratory and glandular tissues of rat.

  1997cited by this paper
• Gap junctions equalize intracellular Na+ concentration in astrocytes

  1997influential reference
• Evidence for the co-localization of another connexin with connexin-43 at astrocytic gap junctions in rat brain.

  1997cited by this paper
• Aquaporins in complex tissues. II. Subcellular distribution in respiratory and glandular tissues of rat.

  1997cited by this paper
• Intracellular sodium homeostasis in rat hippocampal astrocytes.

  1996influential reference
• Mechanisms of H+ and Na+ Changes Induced by Glutamate, Kainate, and d-Aspartate in Rat Hippocampal Astrocytes

  1996influential reference
• Effects of dextran on hippocampal brain slice water, extracellular space, calcium kinetics and histology.

  1995cited by this paper
• Aquaporins: a family of water channel proteins.

  1993cited by this paper
• Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia.

  1993cited by this paper
• Activity-dependent K+ accumulation in the developing rat optic nerve.

  1982cited by this paper

• Rewiring Brain Recovery: Astrocyte–Neuron Metabolic Cooperation in Stroke

  2026cites this paper
• Aquaporins in Nervous System.

  2023cites this paper
• Associations between neuromyelitis optica spectrum disorder, Sjögren's syndrome, and conditions with electrolyte disturbances.

  2023cites this paper
• TGN020 application against aquaporin 4 improved multiple sclerosis by inhibiting astrocytes, microglia, and NLRP3 inflammasome in a cuprizone mouse model.

  2023cites this paper
• Molecular and cellular evolution of the primate dorsolateral prefrontal cortex

  2022cites this paper
• Predictors of overlapping autoimmune disease in Neuromyelitis Optica Spectrum disorder (NMOSD): A retrospective analysis in two inner-city hospitals.

  2022cites this paper
• Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis

  2021cites this paper
• Editorial: Glial Cells, Maladaptive Plasticity, and Neurodegeneration: Mechanisms, Targeted Therapies, and Future Directions

  2021cites this paper
• Safety and efficacy of mycophenolate mofetil in treating neuromyelitis optica spectrum disorders: a protocol for systematic review and meta-analysis

  2020cites this paper
• Safety and efficacy of plasma exchange for the treatment of optic neuritis in neuromyelitis optica spectrum disorders

  2020cites this paper
• Disorders of myelin

  2020cites this paper
• LncRNA NEAT1/miR-128-3p/AQP4 axis regulating spinal cord injury-induced neuropathic pain progression.

  2020cites this paper
• Effect of aquaporin 4 protein overexpression in nigrostriatal system on development of Parkinson’s disease

  2020cites this paper
• Review: Recent advances in the understanding of the pathophysiology of neuromyelitis optica spectrum disorder

  2019cites this paper
• Bursting at the Seams: Molecular Mechanisms Mediating Astrocyte Swelling

  2019cites this paper
• Role of Glutamatergic Excitotoxicity in Neuromyelitis Optica Spectrum Disorders

  2019cites this paper
• MIF -173G/C polymorphism is associated with NMO disease severity.

  2019cites this paper
• Heterogeneity of Astrocytes in Grey and White Matter

  2019cites this paper
• A Rare Presentation of Neuromyelitis Optica Spectrum Disorders

  2018cites this paper
• Neuropathic pruritus: an early indicator of neuromyelitis optica spectrum disorders

  2018cites this paper
• C5a-Preactivated Neutrophils Are Critical for Autoimmune-Induced Astrocyte Dysregulation in Neuromyelitis Optica Spectrum Disorder

  2018cites this paper
• Neuromyelitis Optica and Herpes Simplex Virus 2: A Viral Trigger for Aquaporin-4 Autoimmunity?

  2018cites this paper
• Aquaporins in neurological disorders

  2018cites this paper
• Headache in Neuromyelitis Optica

  2017cites this paper
• Complexity and wide range of neuromyelitis optica spectrum disorders: more than typical manifestations

  2017cites this paper
• High serum creatinine is associated with reduction of vision impaired in patients with NMOSD.

  2017cites this paper
• The link between morphology and complement in ocular disease

  2017cites this paper
• Evidence for Cerebrospinal Fluid Entry Into the Optic Nerve via a Glymphatic Pathway.

  2017cites this paper
• Neuromyelitis Optica: Deciphering a Complex Immune-Mediated Astrocytopathy.

  2017cites this paper
• Aquaporins in Nervous System.

  2017cites this paper
• Nucleus of the solitary tract, medullary reflexes, and clinical implications

  2017cites this paper
• Radiculopathy in neuromyelitis optica. How does anti-AQP4 Ab involve PNS?

  2017cites this paper
• Finding NMO

  2016cites this paper
• AQP 4-IgG : A SPECIFIC AND PATHOGENIC HUMORAL AUTOANTIBODY

  year unknowncites this paper