Development and cellular application of visible-light-controllable HNO releasers based on caged Piloty's acid.

Nitroxyl (HNO) is a gaseous molecule with unique pharmacological functions distinct from those of nitric oxide. Because HNO is highly reactive with biological molecules, spatiotemporally controllable HNO releasers are required. Herein, we report the first visible-light-controllable HNO releasers, based on caged Piloty's acid, and we demonstrate their applicability in living cells.

• Publication year

  2018

• Venue

  Chemical Communications

• Publication date

  2018-09-11

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1039/c8cc04954hPMID 30152479
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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