Supramolecular hydrophobic guest transport system based on pillar[5]arene.

Zhenhui Qi,K. Achazi,R. Haag,Shengyi Dong,C. Schalley

Published 2015 in Chemical Communications

ABSTRACT

A pillar[5]arene-based bioactive guest loading system has been developed, which can increase the solubility of the drug norharmane in aqueous medium, and also enable its pH-stimulated release. Furthermore, this supramolecular transport system reduces the toxicity of loaded guest.

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