Adjuvant, neoadjuvant, and definitive radiation therapy for malignant pleural mesothelioma.

While ionizing radiotherapy (RT) can provide durable local control, the relative radiosensitivity of surrounding organs such as the lungs and heart and the distributed nature of the pleura limit the ability to safely deliver RT for patients with malignant pleural mesothelioma (MPM). Recent advances in the technological sophistication of RT planning and delivery devices have resulted in increased spatial control of irradiation dose that has extended the palliative and definitive applications of RT for patients with MPM. This review will outline the logistical, mechanistic and clinical basics of RT and the clinical trials supporting the use of RT in the multidisciplinary care of patients with MPM.

• Publication year

  2018

• Venue

  Journal of Thoracic Disease

• Publication date

  2018-02-08

• Fields of study

  Medicine

• Identifiers
  DOI 10.21037/jtd.2018.07.65PMID 30206500PMCID PMC6123183
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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