Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation

Essentials Nitric oxide synthesis controls protein disulfide isomerase (PDI) function. Nitric oxide (NO) modulation of PDI controls endothelial thrombogenicity. S‐nitrosylated PDI inhibits platelet function and thrombosis. Nitric oxide maintains vascular quiescence in part through inhibition of PDI.

• Publication year

  2018

• Venue

  Journal of Thrombosis and Haemostasis

• Publication date

  2018-10-12

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1111/jth.14291PMID 30207066PMCID PMC6374154
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• 1 Supplementary Material

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