Morbillivirus-associated lipid pneumonia in Arctic foxes

We describe lipid pneumonia in 5 of 24 Arctic foxes (Vulpes lagopus) in association with morbillivirus infection, and lymphoid depletion in 3 of these 5 foxes. Canine distemper virus (CDV) immunohistochemistry yielded positive staining in lung, lymph nodes, spleen, adipose tissue, and renal pelvic urothelial cells in 5 cases. Liver and bone marrow samples collected from these cases tested positive for morbillivirus by reverse-transcription PCR assay. Strains belonged to the CDV Arctic lineage based on sequencing of the hemagglutinin gene followed by phylogenetic analysis. Phylogenetic analysis of the phosphoprotein gene showed that the identified CDV strains were not closely related to any previously documented strains responsible for outbreaks in different animals in other parts of the world.

• Publication year

  2018

• Venue

  Journal of Veterinary Diagnostic Investigation

• Publication date

  2018-09-12

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1177/1040638718797382PMID 30205787PMCID PMC6505839
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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