Preliminary Evaluation of Platelet Counts of Diabetic Individuals Attending University of Maiduguri Teaching Hospital

Hyperglycaemia hyperactivates platelets functions which in turn participates in the pathophysiology of vasculopathies in diabetics. This study was carried out to investigate the platelet counts of the various diabetic groups attending University of Maiduguri Teaching Hospital and compare to non-diabetic group. This is a case-control study that comprises of 220 subjects. Out of 120 confirmed diabetic subjects, three subgroups of 2 (1.7%) type 1 diabetics, 101 (84.1%) type 2 diabetics and 17 (14.2%) gestational diabetics comprised the test participants while 100 non-diabetic subjects served as control participants. Platelet counts and plasma glucose estimation were carried out using standard testing protocols. Findings from this study indicated no significant difference between the means of platelet counts of the diabetics subgroups and control participants (p>0.05).The mean platelet counts was significantly (p<0.05) lower in patients with type 2 diabetics compared to those with gestational diabetics (315.37±56.13×10 9 cells/l versus 325.82±56.78×10 9 cells/l) (p<0.05). There was a positive but not significant correlation (r= 0.052; p>0.05) between platelet counts and glycemic status of diabetic subjects. Routine platelet counts result is a good index for evaluation thrombotic function of diabetic patients, but more useful in conjunction with testing the overall functionality of the coagulation cascades.

• Publication year

  2016

• Venue

  IOSR Journal of Dental and Medical Sciences

• Publication date

  2016-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.9790/0853-1510035256
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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