Attenuation of murine allergic airway inflammation with a CXCR1/CXCR2 chemokine receptor inhibitor

More than two decades ago, we were amongst the first to report the presence of neutrophils in the airways in severe asthma 1 . However, the nature of contribution of neutrophils to allergic inflammation remained a scientific enigma until quite recently. Neutrophils have long been viewed as terminally differentiated cells that clear extracellular pathogens. However, a growing body of literature indicates that neutrophils regulate innate and adaptive immune responses, and contribute to allergic diseases. This article is protected by copyright. All rights reserved.

• Publication year

  2018

• Venue

  Clinical and Experimental Allergy

• Publication date

  2018-10-05

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/cea.13275PMID 30218547PMCID PMC6660919
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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