A pH-Resolved Colorimetric Biosensor for Simultaneous Multiple Target Detection.

Colorimetric detection has been widely applied in daily life. However, on the other hand, the further development of colorimetric biosensors has been constrained by the lack of multiple detection capabilities. In this work, we proposed a pH-resolved colorimetric biosensor for the first time for the simultaneous detection of four targets, including ochratoxin A (OTA), aflatoxins B1 (AFB1), fumonisin B1 (FB1), and microcystin-LR (MC-LR). With allochroic dyes as the signal indicators, pH value was introduced as the new dimension to control the release of dyes. The concentrations of four targets can be obtained in order by adjusting the pH of the solution. Meanwhile, tedious and high-cost chemical modification processes in the fabrications of biosensors were also avoided by the combination of DNA-directed self-assembly of graphene oxide and magnetic separation. This biosensor provided a simple, rapid, accurate, and low-cost strategy for multiple target detection.

• Publication year

  2018

• Venue

  ACS Sensors

• Publication date

  2018-09-17

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1021/acssensors.8b00717PMID 30221513
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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