Recombinant inbred mouse strains generated from an LG/J and SM/J intercross offer a unique resource to study complex genetic traits such as osteoarthritis (OA). We undertook this study to determine the susceptibility of 14 strains to various phenotypes characteristic of posttraumatic OA. We hypothesized that phenotypic variability is associated with genetic variability.
Evidence for Genetic Contribution to Variation in Posttraumatic Osteoarthritis in Mice
N. Chinzei,M. Rai,S. Hashimoto,E. Schmidt,K. Takebe,J. Cheverud,L. Sandell
Published 2019 in Arthritis & Rheumatology
ABSTRACT
PUBLICATION RECORD
- Publication year
2019
- Venue
Arthritis & Rheumatology
- Publication date
2019-03-01
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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